Patents by Inventor Akemi Mizutani

Akemi Mizutani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spiroimidazolone derivative
    Patent number: 9487517
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: November 8, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake
  • SPIROIMIDAZOLONE DERIVATIVE
    Publication number: 20160016956
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: September 17, 2015
    Publication date: January 21, 2016
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu NISHIMURA, Yoshiaki ISSHIKI, Naoki OKAMOTO, Yoshiyuki FURUTA, Akemi MIZUTANI, Masateru OHTA, Wayne Wen LAI, Tomoya KOTAKE
  • Spiroimidazolone derivative
    Patent number: 9169254
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: October 27, 2015
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake
  • SPIROIMIDAZOLONE DERIVATIVE
    Publication number: 20120270838
    Abstract: The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: April 27, 2010
    Publication date: October 25, 2012
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Toru Esaki, Yoshikazu Nishimura, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta, Akemi Mizutani, Masateru Ohta, Wayne Wen Lai, Tomoya Kotake
  • Intermediate compound for synthesis of viridiofungin a derivative
    Patent number: 8030496
    Abstract: A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. A compound represented by the formula (1-8): wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R?, etc.; and n represents an integer of 0 to 10.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: October 4, 2011
    Assignee: Chugai Seiyaki Kabushiki Kaisha
    Inventors: Tatsuya Kato, Nobuaki Kimura, Akemi Mizutani, Toshihiko Makino, Kenichi Kawasaki, Hiroshi Fukuda, Susumu Komiyama, Takuo Tsukuda
  • Intermediate compound for synthesis of viridiofungin a derivative
    Patent number: 7897783
    Abstract: A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. A compound represented by the formula (1-8): [wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R?, etc.; and n represents an integer of 0 to 10].
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: March 1, 2011
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tatsuya Kato, Nobuaki Kimura, Akemi Mizutani, Toshihiko Makino, Kenichi Kawasaki, Hiroshi Fukuda, Susumu Komiyama, Takuo Tsukuda
  • Intermediate compound for synthesis of viridiofungin a derivative
    Publication number: 20100152457
    Abstract: A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. A compound represented by the formula (1-8): wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R?, etc.; and n represents an integer of 0 to 10.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 17, 2010
    Inventors: Tatsuya Kato, Nobuaki Kimura, Akemi Mizutani, Toshihiko Makino, Kenichi Kawasaki, Hiroshi Fukuda, Susumu Komiyama, Takuo Tsukuda
  • Intermediate compound for synthesis of viridiofungin a derivative
    Publication number: 20100152456
    Abstract: A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. A compound represented by the formula (1-8): wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R?, etc.; and n represents an integer of 0 to 10.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 17, 2010
    Inventors: Tatsuya Kato, Nobuaki Kimura, Akemi Mizutani, Toshihiko Makino, Kenichi Kawasaki, Hiroshi Fukuda, Susumu Komiyama, Takuo Tsukuda
  • Production Process of Compound Having Anti-Hcv Action and Intermediate Thereof
    Publication number: 20080293950
    Abstract: A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. A compound represented by the formula (1-8): [wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R?, etc.; and n represents an integer of 0 to 10].
    Type: Application
    Filed: February 16, 2006
    Publication date: November 27, 2008
    Inventors: Tatsuya Kato, Nobuaki Kimura, Akemi Mizutani, Toshihiko Makino, Kenichi Kawasaki, Hiroshi Fukuda, Susumu Komiyama, Takuo Tsukuda