Patents by Inventor Akhilesh Dixit

Akhilesh Dixit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORAL SOLID MELOXICAM FORMULATIONS FOR THE TREATMENT OF ACUTE PAIN
    Publication number: 20230172943
    Abstract: Oral solid pharmaceutical compositions containing meloxicam co-crystals described herein allow for the use of meloxicam for the treatment of acute pain. In particular, the improved dissolution and bioavailability of the meloxicam co-crystal compositions provide more rapid uptake of meloxicam in vivo as evidenced by increase blood plasma concentrations in a decreased amount of time following administration. A correlation between improved plasma concentrations and in vivo analgesic action are provided for the first time.
    Type: Application
    Filed: April 20, 2021
    Publication date: June 8, 2023
    Applicant: Mylan Specialty L.P.
    Inventors: Richard Allan, Amit Antarkar, Santanu Chakraborty, Abhijit Deshmukh, Matthew A. Hummel, Ashish Jaiswal, Akhilesh Dixit, Ritesh Kakaria, Pankaj Patil, Russ Rackley, Andrew Shaw, Jeffrey P. Smith
  • MELOXICAM CO-CRYSTAL COMPOSITIONS
    Publication number: 20220184095
    Abstract: The solubility and bioavailability properties of meloxicam can be improved by preparing compositions of meloxicam co-crystals and reducing the particle size of (e.g., “nanosizing”) co-crystals. Such compositions with improved dissolution pharmacokinetic properties can be prepared by granulation and blending the co-crystals with extragranular excipients to provide oral solid dosage forms. As a result of the improved properties of the meloxicam oral dosage forms, the compositions may be useful for the treatment of pain, including acute pain.
    Type: Application
    Filed: April 21, 2020
    Publication date: June 16, 2022
    Inventors: Richard ALLAN, Amit ANTARKAR, Santanu CHAKRABORTY, Abhijit DESHMUKH, Akhilesh DIXIT, Matthew A. HUMMEL, Ashish JAISWAL, Ritesh KAKARIA, Pankaj PATIL, Russ RACKLEY, Andrew SHAW, Jeffrey P. SMITH
  • Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders
    Patent number: 9682068
    Abstract: This disclosure relates to a transdermal therapeutic system (TTS) containing pramipexole or related compounds and methods of making the system as well as its use in administering such compounds as a single dose over an extended period, for example, one week. The system comprises an acrylic-based or silicone-based matrix layer containing pramipexole at concentrations of at least about 5 wt. % of the matrix, which is resistant to crystallizing and discoloration of the active ingredient even when stored over long periods.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: June 20, 2017
    Assignee: Mylan Inc.
    Inventors: Abhijit Mukund Deshmukh, Akhilesh Dixit, Prasanna Kumar, Vikram Bindra
  • STORAGE STABLE TRANSDERMAL PATCH OF ROTIGOTINE
    Publication number: 20160136107
    Abstract: Disclosed is a transdermal delivery device comprising a backing layer, a release liner, and an adhesive layer between the backing layer and the release liner, the adhesive layer comprising an active agent solubilized in an adhesive matrix, the adhesive matrix comprising a mixture of biocompatible polymers, wherein the active agent is soluble in at least one of the biocompatible polymers.
    Type: Application
    Filed: June 20, 2014
    Publication date: May 19, 2016
    Applicant: Mylan Technologies, Inc.
    Inventors: Abhijit Deshmukh, Akhilesh Dixit, Rajesh Kumar Bijay, Prasanna Kumar
  • Transdermal Therapeutic System for Extended Dosing of Pramipexole in Treating Neurological Disorders
    Publication number: 20160113908
    Abstract: This disclosure relates to a transdermal therapeutic system (TTS) containing pramipexole or related compounds and methods of making the system as well as its use in administering such compounds as a single dose over an extended period, for example, one week. The system comprises an acrylic-based or silicone-based matrix layer containing pramipexole at concentrations of at least about 5 wt. % of the matrix, which is resistant to crystallizing and discoloration of the active ingredient even when stored over long periods.
    Type: Application
    Filed: May 19, 2014
    Publication date: April 28, 2016
    Inventors: Abhijit Mukund DESHMUKH, Akhilesh DIXIT, Prasanna KUMAR, Vikram BINDRA
  • Pharmaceutical composition
    Publication number: 20070141150
    Abstract: A solid pharmaceutical dosage form comprises a core particle containing at least one pharmaceutical active ingredient and/or excipient that is sensitive to acid, a subcoating containing a chemically reactive component disposed over the core, and an enteric coating over the subcoating.
    Type: Application
    Filed: December 23, 2004
    Publication date: June 21, 2007
    Inventors: Raghupathi Kandarapu, Akhilesh Dixit, Vijay Nasare, Mailatur Mohan
  • Pharmaceutical compositions having a swellable coating
    Publication number: 20050042277
    Abstract: A pharmaceutical dosage form containing a pharmaceutical active that is not stable in the presence of acid comprises a core containing the active and a disintegrant, a swellable coating surrounding the core, and an enteric coating surrounding the swellable coating.
    Type: Application
    Filed: July 16, 2004
    Publication date: February 24, 2005
    Inventors: Irukulla Srinivas, Akhilesh Dixit, Pallempalli Reddy, Billa Reddy, Mailatur Mohan, Kodipyaka Ravinder, Edward Pergament, Vijay Nasare
  • Oral pharmaceutical formulations of acid-labile active ingredients and process for making same
    Publication number: 20050031696
    Abstract: An oral pharmaceutical formulation in dosage form of acid-labile compounds, methods of treating using the formulation and a process for its production are described.
    Type: Application
    Filed: April 22, 2004
    Publication date: February 10, 2005
    Inventors: Ujwal Kolhe, Divi Krishna, Akhilesh Dixit, Abhijit Deshmukh, Narayan Rajput, Mailatur Mohan, Manne Reddy, Muppa Kumar, Koilkonda Purender, Alieti Reddy