Patents by Inventor Akihiko Hattori
Akihiko Hattori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080123088Abstract: There are provided a microchemical system capable of acquiring a highly accurate TLM output value and a method for calculating TLM output thereof. A microchemical system 1 comprises: a microchemical chip having a channel with a depth t in which a sample flows; an exciting light source 13 adapted to irradiate the sample with an exciting light through an objective lens 10 with a numerical aperture NA; a detecting light source 14 adapted to irradiate the sample with a detecting light coaxially with the exciting light through the objective lens 10; and a PD adapted to receive a transmitted light when the detecting light transmits the sample before and after formation of a thermal lens 12. When a TLM output is calculated in the microchemical system 1 on the basis of a received light amount of the PD, the depth t (?m) is set to the range of 75?t?300, the numerical aperture NA is set to the range of 0.04?NA?0.Type: ApplicationFiled: November 16, 2007Publication date: May 29, 2008Applicant: Nippon Sheet Glass Company, LimitedInventors: Masatoshi Nara, Ryo Anraku, Takahiro Asai, Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi, Akihide Hibara, Kazuma Mawatari
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Publication number: 20080124247Abstract: There are provided a chip for micro chemical systems which can obviate the need of alignment at every measurement and can improve the measurement sensitivity and reduce the variation of measurement, and a micro chemical system using the chip. A thermal lens spectrometry system 10 comprises: a micro chemical chip 2 having a groove 1 into which a sample solution is injected; a rod lens 3 disposed on the micro chemical chip 2 at a predetermined spacing above the groove 1; a lens holder 9 disposed above the micro chemical chip 2; a securing section 4; an optical fiber 5; a ferrule 6 secured by the securing section 4 above the rod lens 3; a light source unit 7 connected to the optical fiber 5, and a detection device 8 disposed below the micro chemical chip 2. The securing section 4 comprises a seating 32 laid on the micro chemical chip 2, and a metal split sleeve 33 for fitting the ferrule 6 and the lens holder 9 at the outside thereof.Type: ApplicationFiled: November 13, 2007Publication date: May 29, 2008Applicant: Nippon Sheet Glass Company LimitedInventors: Yoshinori Matsuoka, Jun Yamaguchi, Takashi Fukuzawa, Akihiko Hattori, Takehiko Kitamori
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Patent number: 7339677Abstract: A microchemical system according to which measurement can be carried out with high sensitivity. The microchemical system 1 has a two-wavelength multiplexing device in which gradient index rod lenses 501 and 502 are connected together at an end face of each thereof and a dielectric multi-layer film filter 503 is formed between these end faces. Exciting light and detecting light is multiplexed by the two-wavelength multiplexing device, and then the exciting light and the detecting light are guided to an optical fiber unit 10 through an optical fiber 101 with a single mode. The optical fiber unit 10 has built therein a gradient index rod lens 102 at a leading end thereof, and the exciting light and the detecting light are irradiated onto a sample from the gradient index rod lens 102.Type: GrantFiled: April 21, 2004Date of Patent: March 4, 2008Assignee: Nippon Sheet Glass Co., Ltd.Inventors: Jun Yamaguchi, Akihiko Hattori
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Patent number: 7304734Abstract: A fluorescence analysis optical multiplexer/demultiplexer, a fluorescence analysis optical module, a fluorescence analyzer, a fluorescence/photothermal conversion spectroscopic analyzer, and a fluorescence analysis chip, according to which LIF analysis can be carried out easily and with high sensitivity, and moreover photothermal conversion spectroscopic analysis can be carried out easily and simultaneously with the LIF analysis. A microchemical system 100 as the fluorescence analyzer is comprised of a fluorescence analysis optical module 100a, a probe 50 that condenses exciting light onto a sample solution in a channel 204 inside a fluorescence analysis chip 20, and a sample stage 21 on which the fluorescence analysis chip 20 is mounted.Type: GrantFiled: January 9, 2006Date of Patent: December 4, 2007Assignee: Nippon Sheet Glass Company LimitedInventors: Takashi Fukuzawa, Jun Yamaguchi, Akihiko Hattori, Takao Miwa
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Publication number: 20060289309Abstract: A microchemical system is disclosed that is capable of controlling the flow of a sample solution flowing through a channel in a microchip. In the microchemical system 1, a microchip 7 has therein a T-shaped channel 4 comprised of a main channel 2, a sub-channel 3, and a merging portion 4 where the main channel 2 and the sub-channel 3 merge together. Panel heaters 8 and 9 are installed in a position such as to be able to heat the interior of the sub-channel 3. The sub-channel 3 and the merging portion are subjected to hydrophobic modification treatment. Water is supplied into the main channel 2, and air is supplied into the sub-channel 3.Type: ApplicationFiled: August 30, 2006Publication date: December 28, 2006Applicant: Nippon Sheet Glass Company, LimitedInventors: Takashi Fukuzawa, Jun Yamaguchi, Kenji Uchiyama, Akihiko Hattori
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Patent number: 7142305Abstract: There is provided a microchemical system which dispenses with the optical axis alignment and positioning of the focal point of the detecting light and that of the exciting light, and is capable of carrying out measurement with high sensitivity. The microchemical system includes a channel-formed plate-shaped member containing a sample, an exciting light source that irradiates exciting light onto the sample via a converging lens, a detecting light source that irradiates detecting light onto a thermal lens formed within the sample by the irradiated exciting light, via the converging lens, and detecting means for detecting the irradiated detecting light via the formed thermal lens. The exciting light source and the detecting light source are connected to the converging lens via an optical fiber for propagating the exciting light and the detecting light to the converging lens.Type: GrantFiled: March 25, 2005Date of Patent: November 28, 2006Assignee: Nippon Sheet Glass Company, LimitedInventors: Jun Yamaguchi, Akihiko Hattori
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Patent number: 7092099Abstract: A microchemical system is provided, which can improve the working efficiency of the user. In the microchemical system 1, a plate-shaped element 10 that constitutes an optical unit 1a has an optical wave guide path 20, which acts as an optical path for exciting light and detecting light. An irradiation lens 30 is disposed at an end of the optical wave guide path 20 downstream in the direction of travel of the exciting light and the detecting light, and a channel 40 is located downstream of the irradiation lens 30, through which a liquid containing a sample flows. A detector 50 is disposed at an end of the plate-shaped element 10 downstream of the channel 40 and detects the detecting light for analysis of the sample.Type: GrantFiled: January 27, 2004Date of Patent: August 15, 2006Assignees: Nippon Sheet Glass Co., Ltd., Kanagawa Academy of Science & TechnologyInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Patent number: 7057729Abstract: There is provided that enables high-sensitivity analysis to be carried out, and a photothermal conversion spectroscopic analysis apparatus that is compact in size and is able to implement the photothermal conversion spectroscopic analysis method. Exciting light and detecting light are convergently irradiated onto the sample by a converging lens. The sample is analyzed using a change in intensity of the detecting light due to refraction upon passing through the thermal lens produced through the convergent irradiation of the exciting light. A molar absorption coefficient of the sample at a wavelength of the exciting light is a predetermined number of times greater than a molar absorption coefficient of the sample at a wavelength of the detecting light.Type: GrantFiled: May 27, 2003Date of Patent: June 6, 2006Assignee: Nippon Sheet Glass Co., Ltd.Inventors: Jun Yamaguchi, Akihiko Hattori
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Publication number: 20060109465Abstract: A fluorescence analysis optical multiplexer/demultiplexer, a fluorescence analysis optical module, a fluorescence analyzer, a fluorescence/photothermal conversion spectroscopic analyzer, and a fluorescence analysis chip, according to which LIF analysis can be carried out easily and with high sensitivity, and moreover photothermal conversion spectroscopic analysis can be carried out easily and simultaneously with the LIF analysis. A microchemical system 100 as the fluorescence analyzer is comprised of a fluorescence analysis optical module 100a, a probe 50 that condenses exciting light onto a sample solution in a channel 204 inside a fluorescence analysis chip 20, and a sample stage 21 on which the fluorescence analysis chip 20 is mounted.Type: ApplicationFiled: January 9, 2006Publication date: May 25, 2006Applicant: Nippon Sheet Glass Company, LimitedInventors: Takashi Fukuzawa, Jun Yamaguchi, Akihiko Hattori, Takao Miwa
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Patent number: 7012692Abstract: It is an object to provide a photothermal conversion spectroscopic analysis method that enables measurement to be carried out with high sensitivity, and a photothermal conversion spectroscopic analysis apparatus that carries out the method. The photothermal conversion spectroscopic analysis apparatus is comprised of an exciting light source 111, a chopper 112 that is disposed close to the exciting light source 111 in the optical path of exciting light emitted from the exciting light source 111, a mirror 114 that changes the direction of travel of the exciting light, a detecting light source 120, a dichroic mirror 113 that has detecting light from the detecting light source 120 incident thereon and makes the exciting light and the detecting light coaxial, a lens 10 that has a suitable amount of chromatic aberration, and a holder 15 that holds the lens 10 such as to enable adjustment along three axes.Type: GrantFiled: December 12, 2003Date of Patent: March 14, 2006Assignees: Nippon Sheet Glass Co., Ltd., Kanagawa Academy of Science & TechnologyInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20050219539Abstract: There is provided a microchemical system which dispenses with the optical axis alignment and positioning of the focal point of the detecting light and that of the exciting light, and is capable of carrying out measurement with high sensitivity. The microchemical system includes a channel-formed plate-shaped member containing a sample, an exciting light source that irradiates exciting light onto the sample via a converging lens, a detecting light source that irradiates detecting light onto a thermal lens formed within the sample by the irradiated exciting light, via the converging lens, and detecting means for detecting the irradiated detecting light via the formed thermal lens. The exciting light source and the detecting light source are connected to the converging lens via an optical fiber for propagating the exciting light and the detecting light to the converging lens.Type: ApplicationFiled: March 25, 2005Publication date: October 6, 2005Applicant: Nippon Sheet Glass Company, LimitedInventors: Jun Yamaguchi, Akihiko Hattori
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Patent number: 6941041Abstract: There is provided a gradient index rod lens unit having a desired chromatic aberration. The gradient index rod lens unit is comprised of two gradient index rod lenses 11 and 12 with different chromatic aberrations and the entire lengths thereof adjusted, which are disposed in series with the optical axes thereof in alignment. The chromatic aberration of the gradient index rod lens unit can be set to a value falling within chromatic aberration ranges inherently possessed by the respective gradient index rod lenses 11 and 12.Type: GrantFiled: January 9, 2004Date of Patent: September 6, 2005Assignee: Nippon Sheet Glass Co., Ltd.Inventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori
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Patent number: 6930778Abstract: A microchemical system is provided, which can improve the working efficiency of the user and can be designed compact in size. The microchemical system is provided with an optical fiber 10 with a gradient index rod lens 102 mounted on an end thereof. The lens-possessing optical fiber 10 is comprised of an optical fiber 101 that transmits exciting light and detecting light in the single mode, and a ferrule 103 for expanding the outer diameter of the optical fiber 101 to the same value as that of the gradient index rod lens 102. The gradient index rod lens 102 and the optical fiber 101 are rigidly joined together by means of a sleeve 104.Type: GrantFiled: December 10, 2003Date of Patent: August 16, 2005Assignees: Nippon Sheet Glass Co., Ltd., Kanagawa Academy of Science & TechnologyInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20050140971Abstract: A microchemical system chip and a microchemical system that can be reduced in size while improving measurement sensitivity. The microchemical system chip 1 is comprised of a plate-shaped glass substrate 10, and the glass substrate 10 has a U-shaped channel 11 therein. The U-shaped channel 11 is comprised of a longitudinal channel 11a, and a pair of transverse channels 11b and 11c that are connected to the two ends of the longitudinal channel 11a. The glass substrate 10 has therein two voids provided coaxially with the longitudinal channel 11a near the two ends of the longitudinal channel 11a, and gradient index rod lenses 14 and 15 are housed respectively in the two voids. An optical fiber 16 that propagates detecting light emitted from a light source is connected to the gradient index rod lens 14, and an optical fiber 17 that leads detecting light received by the gradient index rod lens 15 to a detector is connected to the gradient index rod lens 15.Type: ApplicationFiled: September 17, 2004Publication date: June 30, 2005Applicant: NIPPON SHEET GLASS COMPANY, LIMITEDInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20040257575Abstract: A microchemical system is provided, which can improve the working efficiency of the user. In the microchemical system 1, a plate-shaped element 10 that constitutes an optical unit la has an optical wave guide path 20, which acts as an optical path for exciting light and detecting light. An irradiation lens 30 is disposed at an end of the optical wave guide path 20 downstream in the direction of travel of the exciting light and the detecting light, and a channel 40 is located downstream of the irradiation lens 30, through which a liquid containing a sample flows. A detector 50 is disposed at an end of the plate-shaped element 10 downstream of the channel 40 and detects the detecting light for analysis of the sample.Type: ApplicationFiled: January 27, 2004Publication date: December 23, 2004Applicants: NIPPON SHEET GLASS CO., LTD., KANAGAWA ACADEMY OF SCIENCE & TECHNOLOGYInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20040233542Abstract: There is provided a gradient index rod lens unit having a desired chromatic aberration. The gradient index rod lens unit is comprised of two gradient index rod lenses 11 and 12 with different chromatic aberrations and the entire lengths thereof adjusted, which are disposed in series with the optical axes thereof in alignment. The chromatic aberration of the gradient index rod lens unit can be set to a value falling within chromatic aberration ranges inherently possessed by the respective gradient index rod lenses 11 and 12.Type: ApplicationFiled: January 9, 2004Publication date: November 25, 2004Applicant: NIPPON SHEET GLASS CO., LTD.Inventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori
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Publication number: 20040233450Abstract: It is an object to provide a photothermal conversion spectroscopic analysis method that enables measurement to be carried out with high sensitivity, and a photothermal conversion spectroscopic analysis apparatus that carries out the method. The photothermal conversion spectroscopic analysis apparatus is comprised of an exciting light source 111, a chopper 112 that is disposed close to the exciting light source 111 in the optical path of exciting light emitted from the exciting light source 111, a mirror 114 that changes the direction of travel of the exciting light, a detecting light source 120, a dichroic mirror 113 that has detecting light from the detecting light source 120 incident thereon and makes the exciting light and the detecting light coaxial, a lens 10 that has a suitable amount of chromatic aberration, and a holder 15 that holds the lens 10 such as to enable adjustment along three axes.Type: ApplicationFiled: December 12, 2003Publication date: November 25, 2004Applicants: NIPPON SHEET GLASS CO., LTD., KANAGAWA ACADEMY OF SCIENCE & TECHNOLOGYInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20040233449Abstract: A microchemical system is provided, which can improve the working efficiency of the user and can be designed compact in size. The microchemical system is provided with an optical fiber 10 with a gradient index rod lens 102 mounted on an end thereof. The lens-possessing optical fiber 10 is comprised of an optical fiber 101 that transmits exciting light and detecting light in the single mode, and a ferrule 103 for expanding the outer diameter of the optical fiber 101 to the same value as that of the gradient index rod lens 102. The gradient index rod lens 102 and the optical fiber 101 are rigidly joined together by means of a sleeve 104.Type: ApplicationFiled: December 10, 2003Publication date: November 25, 2004Applicants: NIPPON SHEET GLASS CO., LTD., KANAGAWA ACADEMY OF SCIENCE & TECHNOLOGYInventors: Jun Yamaguchi, Akihiko Hattori, Takehiko Kitamori, Manabu Tokeshi
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Publication number: 20040196466Abstract: A microchemical system according to which measurement can be carried out with high sensitivity. The microchemical system 1 has a two-wavelength multiplexing device in which gradient index rod lenses 501 and 502 are connected together at an end face of each thereof and a dielectric multi-layer film filter 503 is formed between these end faces. Exciting light and detecting light is multiplexed by the two-wavelength multiplexing device, and then the exciting light and the detecting light are guided to an optical fiber unit 10 through an optical fiber 101 with a single mode. The optical fiber unit 10 has built therein a gradient index rod lens 102 at a leading end thereof, and the exciting light and the detecting light are irradiated onto a sample from the gradient index rod lens 102.Type: ApplicationFiled: April 21, 2004Publication date: October 7, 2004Applicant: NIPPON SHEET GLASS CO., LTD.Inventors: Jun Yamaguchi, Akihiko Hattori
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Publication number: 20040175297Abstract: A microchemical system is provided according to which to which an apparatus that is used by the microchemical system can be reduced in size, and measurement accuracy can be improved. The microchemical system 1 has an irradiation part 1a that irradiates exciting light and detecting light onto a sample solution in a channel 204 that is inside a microchemical system chip 20. The irradiation part 1a has an exciting light source 106 that outputs the exciting light, which has a wavelength of 532 nm, and a detecting light source 107 that outputs the detecting light, which has a wavelength of 635 nm. The exciting light source 106 is comprised of a fiber laser 502 that lases laser light of wavelength 1064 nm, and a poled fiber 503 that converts laser light received from the fiber laser 502 into a second harmonic. The fiber laser 502 is comprised of a laser diode 501 that lases laser light of wavelength 810 nm, and a double clad fiber 601 having fiber Bragg gratings 602a and 602b formed at opposite ends thereof.Type: ApplicationFiled: March 4, 2003Publication date: September 9, 2004Applicant: NIPPON SHEET GLASS CO., LTD.Inventors: Jun Yamaguchi, Tetsuro Kawahara, Akihiko Hattori, Chandrasekhar Rpychoudhuri