Patents by Inventor Akihiko Saiga

Akihiko Saiga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Remedies for arteriosclerosis
    Publication number: 20040248898
    Abstract: New pharmaceutical compositions for treating or preventing arteriosclerosis are provided.
    Type: Application
    Filed: September 22, 2003
    Publication date: December 9, 2004
    Inventors: Akihiko Saiga, Takashi Ono, Katsutoshi Yamada, Kohji Hanasaki
  • DNA molecule relating to suppression of gene expression and novel protein
    Patent number: 6218522
    Abstract: A DNA molecule having a gene expression repressing function derived from human T-cell leukemia virus type I (HTLV-I) existing in a region which is missing in a mutant provirus that is expressing p21Xm RNA but exists in the genome of a complete provirus, and a plasmid including the DNA molecule are provided. Furthermore, a novel protein (TRP-1) which specifically binds to U5RE and a structural gene for the protein is provided, which can be useful for elucidation of the transcription repression activity and elucidation of the oncogenesis mechanism of neurocytes, in which a transcriptional repressive region (U5RE) existing in the U5 region of human T-cell leukemia virus type I gene LTR is involved. Furthermore, an expression vector including the gene, a transformant into which the expression vector is introduced, and a process for producing the TRP-1 protein using the transformant are provided.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: April 17, 2001
    Assignee: Shionogi & Co., Ltd.
    Inventors: Akihiko Saiga, Satoshi Orita, Hisanaga Igarashi, Kouichi Okumura, Gaku Sakaguchi
  • DNA molecule relating to suppression of gene expression and novel protein
    Patent number: 6090783
    Abstract: A DNA molecule having a gene expression repressing function derived from human T-cell leukemia virus type I (HTLV-I) existing in a region which is missing in a mutant provirus that is expressing p21Xm RNA but exists in the genome of a complete provirus, and a plasmid including the DNA molecule are provided. Furthermore, a novel protein (TRP-1) which specifically binds to U5RE and a structural gene for the protein is provided, which can be useful for elucidation of the transcription repression activity and elucidation of the oncogenesis mechanism of neurocytes, in which a transcriptional repressive region (U5RE) existing in the U5 region of human T-cell leukemia virus type I gene LTR is involved. Furthermore, an expression vector including the gene, a transformant into which the expression vector is introduced, and a process for producing the TRP-1 protein using the transformant are provided.
    Type: Grant
    Filed: July 23, 1998
    Date of Patent: July 18, 2000
    Assignee: Shionogi & Co., Ltd.
    Inventors: Akihiko Saiga, Satoshi Orita, Hisanaga Igarashi, Kouichi Okumura, Gaku Sakaguchi