Abstract: The present disclosure proposes a mass spectrometer including a linear ion trap section and an analyzer that analyzes the ions ejected from the linear ion trap section having a multipole rod electrode including a plurality of segments arranged in a direction of a center axis of the linear ion trap section. A first radio frequency voltage in opposite phase is applied to adjacent rod electrodes. An electrostatic voltage having the same amplitude and a second radio frequency voltage are applied to the segments having the same position in the direction of the center axis. The electrostatic voltage is applied to the segments such that the electrostatic voltage decreases from an inlet to an outlet of the linear ion trap section. The second radio frequency voltage is applied to the segments such that the second radio frequency voltage increases from the inlet to the outlet of the linear ion trap section.

Abstract: An object of the present invention is to provide a test method capable of efficiently performing a step of evaluating a surface state of a dispensing probe provided in a dispensing apparatus. In the test method according to the present invention, a first solution in which a coloring matter is dissolved is dispensed to a first container in advance by a first dispensing probe, a second solution in which a coloring matter is not dissolved is dispensed to a second container in advance by the first dispensing probe and then the first solution and the second solution are respectively sucked and discharged by a second dispensing probe. After that, a surface state of the second dispensing probe is evaluated by acquiring an amount of the coloring matter collected by the second solution (see FIG. 2).

Abstract: A spectroscopic analysis system includes: an operation panel configured to receive an input of at least one of an upper limit value of a measurement period of a spectroscopic analysis spectrum or a lower limit value of measurement accuracy as a user setting condition related to measurement of the spectroscopic analysis spectrum of a sample; and a control unit configured to derive a predetermined recommended measurement condition that satisfies the user setting condition and cause a display unit to display the recommended measurement condition, in which the recommended measurement condition is at least one of a wavelength range of light to be used for measurement of the spectroscopic analysis spectrum, a sampling interval of a wavelength of the light, a slit width of a diffraction grating of a spectroscope that disperses the light, or a sweep speed of the wavelength of the light.

Abstract: Provided is a pretreatment method for structural analysis of a protein, including chemical modifying and fragmenting a protein to be analyzed, in which in the fragmenting, the protein is treated at a temperature of 60 to 99° C. in the presence of a heat-resistant protease that has four or more cleavage sites and is soluble or immobilized on a carrier.

Abstract: An object of the present invention is to provide a technology in which an amount of pigment carried from a pigment solution can be accurately measured at the time of testing a surface state of a dispensing probe on the basis of the amount of carried pigment. In a test method according to the present invention, a surface state of a dispensing probe is evaluated on the basis of an amount of pigment carried from an acidic pigment solution into a solution including no pigment.

Abstract: An ultrasonic transducer holder, which is an embodiment, has a detachable container for containing a liquid sample, and transmits an ultrasonic wave. The ultrasonic transducer holder includes an ultrasonic transducer that emits an ultrasonic wave, and a protective layer that is fixed to the ultrasonic transducer and transmits the ultrasonic wave to the container. The protective layer includes a first surface that is a surface to which the ultrasonic transducer is fixed, and a second surface that is a back surface of the first surface and is designed to fix the container via a contact medium.

Abstract: The object of the invention is to perform, rapidly and at a low cost, a pretreatment of an analysis sample containing a turbid substance. Provided is an analysis sample pretreatment apparatus in which a clarified liquid is obtained by removing a turbid substance from an analysis sample. The analysis sample pretreatment apparatus includes a cell configured to store the analysis sample, and a cell holder in which at least a part of a housing is opened to mount the cell. The cell holder includes an ultrasonic wave transducer and an ultrasonic wave reflection plate that are disposed on facing plane pairs while sandwiching the cell mounted inside the cell holder. The cell includes a first opening unit from which the analysis sample flows in, a second opening unit from which the clarified liquid flows out, and a third opening unit from which the turbid substance is discharged.

Abstract: Provided is an automatic analysis device that reduces the used water amount when cleaning the outside of a probe. An automatic analysis device, including a probe that performs suction and discharge of a sample or a reagent and a cleaning nozzle that discharges cleaning water toward the outside of the probe, includes a first discharging step of starting discharge of the cleaning water from the cleaning nozzle when the tip of the probe is at a first height position and a second discharging step of starting discharge of the cleaning water from the cleaning nozzle when the tip of the probe is at a second height position higher than the first height position, and is provided with a discharge stopping step of stopping the discharge of the cleaning water from the cleaning nozzle between the first discharging step and the second discharging step.

Abstract: An arithmetic expression used for estimating a target item of a specimen is more easily incorporated into an optical measurement system. An optical measurement instrument includes an optical analysis unit configured to perform an optical analysis on a specimen and measure an intensity of light as a result of the optical analysis, and an arithmetic processing unit configured to download an arithmetic expression from a server device via a network, and perform a quantitative analysis on a target substance contained in the specimen by substituting the result of the optical analysis by the optical analysis unit into the arithmetic expression.

Abstract: It is possible to reduce a burden on a user in performing a spectroscopic analysis of a liquid sample. There is provided an analysis cell that is detachable and replaceable with respect to an analysis unit and accommodates a liquid sample, the analysis cell including a first wall surface pair that is made of a material transmitting a light, and a second wall surface pair for propagating an ultrasonic wave to the accommodated liquid sample, in which a first wall surface and a second wall surface forming the second wall surface pair and facing each other, are formed of materials having different acoustic impedances.

Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a bolt-clamped Langevin type transducer (BLT) 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.

Abstract: Since a detergent is a consumption article, it is desirable that a use amount of the detergent be as small as possible in a limit that the washing effect is not substantially reduced. Provided is an automatic analyzer which includes a syringe pump which is connected to a probe and performs the body aspiration and discharge, a feed pump which feeds washing water for washing the inside of the probe to the probe via the syringe pump and a controller which controls the dispensing mechanism and the syringe pump, in which the controller, in a case of washing the probe by sucking a detergent in the probe a plurality of times, controls the syringe pump so as to discharge the detergent after sucking the detergent and to suck the next detergent without feeding the washing water to the probe by the feed pump.

Abstract: An object of the invention is to provide an optical analysis method and an optical analysis system capable of accurately performing an optical analysis by using transmitted light even though a sample contains a turbid substance. The optical analysis method of the present disclosure is an optical analysis method for irradiating a sample s containing a turbid substance in a cell 11 with light and performing optical analysis on the sample s by using transmitted light of the light. The optical analysis method includes: exciting the sample s in the cell 11 by irradiation with ultrasonic waves while adjusting a frequency of the ultrasonic waves such that an intensity of the transmitted light is maximized, and then performing the optical analysis in a state where the sample s is irradiated with ultrasonic waves of this adjusted frequency.

Abstract: An object of the present invention is to provide a test method capable of efficiently performing a step of evaluating a surface state of a dispensing probe provided in a dispensing apparatus. In the test method according to the present invention, a first solution in which a coloring matter is dissolved is dispensed to a first container in advance by a first dispensing probe, a second solution in which a coloring matter is not dissolved is dispensed to a second container in advance by the first dispensing probe and then the first solution and the second solution are respectively sucked and discharged by a second dispensing probe. After that, a surface state of the second dispensing probe is evaluated by acquiring an amount of the coloring matter collected by the second solution (see FIG. 2).

Abstract: In order to analyze a solution component and a scatterer component in a liquid sample more quickly, there is provided an optical analysis device including a light source unit configured to irradiate a liquid sample with light; a first light receiving unit configured to receive transmitted light emitted from the light source unit and transmitted through the liquid sample; a second light receiving unit configured to receive scattered light emitted from the light source unit and scattered by a scatterer in the liquid sample; an ultrasonic irradiation unit configured to irradiate the liquid sample with an ultrasonic wave; a reflection plate configured to reflect the ultrasonic wave that is emitted from the ultrasonic irradiation unit and propagated through the liquid sample; and a control unit configured to control the light source unit, the first light receiving unit, the second light receiving unit, and the ultrasonic irradiation unit.

Abstract: An object of the present invention is to provide a technology in which an amount of pigment carried from a pigment solution can be accurately measured at the time of testing a surface state of a dispensing probe on the basis of the amount of carried pigment. In a test method according to the present invention, a surface state of a dispensing probe is evaluated on the basis of an amount of pigment carried from an acidic pigment solution into a solution including no pigment.

Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a bolt-clamped Langevin type transducer (BLT) 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.

Abstract: Since a detergent is a consumption article, it is desirable that a use amount of the detergent be as small as possible in a limit that the washing effect is not substantially reduced. Provided is an automatic analyzer which includes a syringe pump which is connected to a probe and performs the body aspiration and discharge, a feed pump which feeds washing water for washing the inside of the probe to the probe via the syringe pump and a controller which controls the dispensing mechanism and the syringe pump, in which the controller, in a case of washing the probe by sucking a detergent in the probe a plurality of times, controls the syringe pump so as to discharge the detergent after sucking the detergent and to suck the next detergent without feeding the washing water to the probe by the feed pump.

Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a BLT 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.

Abstract: Human labor and time can be reduced, and a high-accuracy numerical model can be created. Provided is a pseudo sample creation method including mixing a pre-culture liquid medium that is not used to culture a sample, a post-culture liquid medium that is used to culture the sample, and an additive containing at least one of saccharides, an amino acid, a metabolite, and protein with one another to create a pseudo sample. In addition, provided is a numerical model creation system including: a spectrometer that acquires spectral data of a pseudo sample; a reference value measuring device that measures a reference value of the pseudo sample; and an analyzer that creates a numerical model representing a correlation between the spectral data and the reference value based on the spectral data and the reference values obtained from a plurality of pseudo samples.