Abstract: Provided is a medical device capable of easily changing a position of the device inside a biological lumen and effectively removing a cut object. The medical device for removing the object in the biological lumen has a drive shaft, a cutting portion, a first housing that accommodates the drive shaft to be rotatable, a second housing that is rotatable with respect to the first housing, and a support portion that supports the first housing and the second housing. The second housing and the support portion relatively move along an axis to restrict relative rotation of the first housing and the second housing. The support portion supports the second housing to be rotatable around the axis.

Abstract: The present disclosure provides a printed material having a high-definition uneven pattern including expanded portions and a method for manufacturing the printed material. A method for manufacturing a printed material includes a step of preparing a thermal transfer sheet including a substrate and a transfer layer that is disposed on one surface side of the substrate and includes a layer containing foamable particles, and a step of heating the thermal transfer sheet to transfer the transfer layer of the thermal transfer sheet in a prescribed pattern a plurality of times onto a transfer receiving body to thereby form a layered body including a plurality of the transfer layers stacked one on another.

Abstract: The present invention addresses the problem of providing, for instance, a mammalian cell preservation solution that can effectively suppress a decrease in cell viability occurring when mammalian cells are preserved in liquid or a decrease in self-renewal potential occurring when mammalian stem cells are preserved in liquid, and that is less likely to cause a harmful effect on the life of a mammal at the time of in vivo administration of mammalian cells to the mammal. This solution involves preserving a mammalian cell by using a mammalian cell preservation solution comprising trehalose or a derivative thereof, or a salt thereof and a hydrogen carbonate, such as sodium bicarbonate, as a pH modifier, and having a pH of from 6.5 to 8.5.

Abstract: A plurality of side modules include a first module, a second module and a third module extending between the first module and the second module in the carbody longitudinal direction and joined to the first module and the second module. A lower end portion of the first module and a lower end portion of the second module oppose and are joined to a floor bodyshell. A lower end portion of a region of the third module opposes the floor bodyshell, the region being located between the first module and the second module. The lower end portion of the region of the third module is freer with respect to the floor bodyshell than the lower end portion of the first module and the lower end portion of the second module. The third module is supported by the floor bodyshell through the first module and the second module.

Abstract: A plurality of side modules include a first module, a second module and a third module extending between the first module and the second module in the carbody longitudinal direction and joined to the first module and the second module. A lower end portion of the first module and a lower end portion of the second module oppose and are joined to a floor bodyshell. A lower end portion of a region of the third module opposes the floor bodyshell, the region being located between the first module and the second module. The lower end portion of the region of the third module is freer with respect to the floor bodyshell than the lower end portion of the first module and the lower end portion of the second module. The third module is supported by the floor bodyshell through the first module and the second module.

Abstract: Disclosed are novel techniques for high-precision sex determination and age estimation using facial images. The disclosed age estimation method includes: a step in which facial image data of a subject is acquired; a step in which spatial frequency intensities are calculated from the acquired facial image data; and a step in which the estimated age of the subject is calculated by applying the calculated spatial frequency intensities obtained from the facial image data.

Abstract: Disclosed are novel techniques for high-precision sex determination and age estimation using facial images. The disclosed age estimation method includes: a step in which facial image data of a subject is acquired; a step in which spatial frequency intensities are calculated from the acquired facial image data; and a step in which the estimated age of the subject is calculated by applying the calculated spatial frequency intensities obtained from the facial image data.

Abstract: The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, wherein R1, R2, R3, R4, R5, and R6 each independently represent a hydrogen atom or a C1-4 alkyl group, and a skin preparation for external use comprising the dendrite elongation inhibitor for melanocytes as an active ingredient.

Abstract: To increase a tissue regeneration ability of a living body such as a collagens production ability of fibroblast in the dermis in a skin defect area typified by a large wrinkle or wound, a flavanone derivative such as farrerol is used as an active ingredient of an external preparation for skin. Further, to efficiently screen a substance having an excellent effect on promoting wound healing, the remodeling action of collagen fiber bundle is tested by using skin wound model.

Abstract: The present invention relates to an external preparation for skin comprising a compound, such as centaureidin(5,7-dihydroxy-3,6-dimethoxy-2-(5-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one); 5,7-dihydroxy-3,6,8-trimethoxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; 3,5-diethoxy-6,7-dimethoxy-2-(5-ethoxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; and 5,6-dihydroxy-3,7-dimethoxy-2-(5-hydroxy-2,4-dimethoxyphenyl)-4H-1-benzopyran-4-one; and/or salt thereof and 4-n-butyl resorcinol and/or a salt thereof. The present invention provides an external preparation for skin having a function as a substantial lightening cosmetic that exerts whitening action of inhibiting excessive melanin production and keeping natural-looking whiteness.

Abstract: It is intended to provide a method whereby the skin conditions (for example, loss in the skin elasticity, wrinkle formation possibility, insufficient tightness in dermal collagen fiber bundles, or the like) can be exactly and conveniently assessed. It is also intended to provide a method whereby the wrinkle-improvement effect of a test substance can be exactly and conveniently evaluated. The skin conditions are assessed by using the expression amount of an adhesion factor in skin cells as an indication. The wrinkle reducing effect of a test substance is evaluated by using the expression amount of an adhesion factor in skin cells in the presence of the test substance as an indication.

Abstract: To increase a tissue regeneration ability of a living body such as a collagens production ability of fibroblast in the dermis in a skin defect area typified by a large wrinkle or wound, a flavanone derivative such as farrerol is used as an active ingredient of an external preparation for skin. Further, to efficiently screen a substance having an excellent effect on promoting wound healing, the remodeling action of collagen fiber bundle is tested by using skin wound model.

Abstract: A charge control agent comprises a monoazo metals-compound including a monoazo compound represented by the following formula [I]: and metals of a metallic element or a metalloid coordinating to the monoazo compound. A toner for developing an electrostatic image comprises: the charge control agent including the monoazo compound and metals of the metallic element or the metalloid coordinating to the monoazo compound, a resin for the toner and a colorant.

Abstract: Monoazo metal complex compound containing composition, the incidence of skin sensitization in a skin sensitization potential test based on the maximization method of said composition being not more than 20% and method for producing said composition which comprises a step for removing impurity substances using an alcoholic organic solvent; charge control agent comprising said composition and toner containing said charge control agent; coloring agent containing said composition and colored thermoplastic resin composition containing said coloring agent.

Abstract: The present invention relates to an external preparation for skin comprising a compound, such as centaureidin(5,7-dihydroxy-3,6-dimethoxy-2-(5-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one); 5,7-dihydroxy-3,6,8-trimethoxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; 3,5-diethoxy-6,7-dimethoxy-2-(5-ethoxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; and 5,6-dihydroxy-3,7-dimethoxy-2-(5-hydroxy-2,4-dimethoxyphenyl)-4H-1-benzopyran-4-one; and/or salt thereof and 4-n-butyl resorcinol and/or a salt thereof. The present invention provides an external preparation for skin having a function as a substantial lightening cosmetic that exerts whitening action of inhibiting excessive melanin production and keeping natural-looking whiteness.

Abstract: The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, wherein R1, R2, and R3 each independently represent a C1-4 alkyl group or hydrogen atom, and a skin preparation for external use comprising the dendrite elongation inhibitor for melanocytes as an active ingredient.

Abstract: The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, wherein R1, R2, R3, R4, R5, and R6 each independently represent a hydrogen atom or a C1-4 alkyl group, and a skin preparation for external use comprising the dendrite elongation inhibitor for melanocytes as an active ingredient.