Abstract: The invention aims to provide a non-destructive method of testing and analysing, amongst other things, cell types such as pluripotent cells, including differentiated cells and MSCs. The invention also aims to provide a non-destructive method to test and analyse the cell conditions, such as aging, activity, multipotency, differentiated directivity and effectiveness. Possibility of analysing cell types or cell conditions without destroying the cells by analyzing glycan profile, which is acquired from glycoconjugates secreted from cells in culture mediums, using microarrays with glycan binding protein, on the surface was discovered.

Abstract: Provided is a method for preparing functional hepatic (progenitor) cells or functional small intestinal epithelial (progenitor) cells, comprising the step of culturing an isolated cell population comprising hepatic (progenitor) cells or small intestinal epithelial (progenitor) cells in the presence of an antibiotic. Also, provided is a substantially homogeneous isolated cell population comprising functional hepatic progenitor cells, wherein an expression level of CYP3A4 in the functional hepatic progenitor cells is increased by at least 5 times the expression level thereof in a HeaRG(R) cell line.

Abstract: A gut organoid includes a tissue structure that encloses a cavity. A method of using the gut organoid includes providing a test drug to the gut organoid in the presence of a buffer solution so that liquid comprising the test drug enters into the cavity, and collecting and analyzing the liquid in the cavity. A method for producing the gut organoid includes plating cells on a cell culture substrate including a surface on which a cell-adhesive region and a non-cell-adhesive region surrounding the cell-adhesive region are formed, and culturing the cells plated on the cell culture substrate so as to induce differentiation of the cells.

Abstract: In an information processing system, plural information processing devices are mutually connected by an SMP connection mechanism. Each of the information processing devices includes a control device (FPGA) having a synchronous register that shows the state of a control signal of the information processing device and an internode communication access control unit that transmits first synchronous packets with the content of the synchronous register reflected to the other information processing devices at predetermined time intervals, receives second synchronous packets from the other information processing devices, and reflects the content of the received second synchronous packets on the synchronous register.

Abstract: A system having an SMP connection made among each information processing apparatus in units of a module including a CPU, a main memory, an HDD and the like, allows use of the HDDs distributed in the system as a single disk. The SMP connection is made among information processing apparatuses each including one or more CPUs, a main memory, one or more storage devices, and a storage device controller that controls the storage device. The storage device controller in a certain information processing apparatus controls the storage device in the information processing apparatus and the storage device in another information processing apparatus. Each information processing apparatus includes a storage device switch for exclusively switching which of the storage device controller in the information processing apparatus and the storage device controller in another information processing apparatus is connected to the storage device in the information processing apparatus.

Abstract: In an information processing system, plural information processing devices are mutually connected by an SMP connection mechanism. Each of the information processing devices includes a control device (FPGA) having a synchronous register that shows the state of a control signal of the information processing device and an internode communication access control unit that transmits first synchronous packets with the content of the synchronous register reflected to the other information processing devices at predetermined time intervals, receives second synchronous packets from the other information processing devices, and reflects the content of the received second synchronous packets on the synchronous register.

Abstract: A system having an SMP connection made among each information processing apparatus in units of a module including a CPU, a main memory, an HDD and the like, allows use of the HDDs distributed in the system as a single disk. The SMP connection is made among information processing apparatuses each including one or more CPUs, a main memory, one or more storage devices, and a storage device controller that controls the storage device. The storage device controller in a certain information processing apparatus controls the storage device in the information processing apparatus and the storage device in another information processing apparatus. Each information processing apparatus includes a storage device switch for exclusively switching which of the storage device controller in the information processing apparatus and the storage device controller in another information processing apparatus is connected to the storage device in the information processing apparatus.

Abstract: A computer system comprises two or more computers including at least one standby computer and a management computer which controls the computers. The management computer manages unique identification information which is assigned to an Ethernet controller of each computer. When a failure has occurred to an active computer, the management computer sets the unique identification information which has been assigned to the Ethernet controller of the failed computer to the Ethernet controller of the standby computer and the standby computer boots up a software image for the failed computer by use of the unique identification information which has been set to its Ethernet controller by the management computer.

Abstract: An object of the present invention is to provide a method for diagnosing endometrial cancer by comprehensively analyzing the glycan structures of glycoprotein with the normal endometrium and endometrial cancers (well-differentiated/poorly-differentiated), using the lectin microarray system. The present invention provides a method for diagnosing or determining the state of normal endometrium or endometrial cancer/cancer stages by glycan profiling using a structure of a glycoprotein in a sample as an indicator.

Abstract: To control the differentiation of mesenchymal stem cells into steroid hormone producing cells. Mesenchymal stem cells can be differentiated into steroid hormone-producing cells by being stimulated by a transcriptional factor (SF-1), preferably by the transcriptional factor (SF-1) and cAMP. The present invention is a method for differentiating mesenchymal stem cells into steroid hormone producing cells, comprising stimulating the mesenchymal stem cells by the transcriptional factor (SF-1). The mesenchymal stem cells may be further stimulated by cAMP.

Abstract: A computer system comprises two or more computers including at least one standby computer and a management computer which controls the computers. The management computer manages unique identification information which is assigned to an Ethernet controller of each computer. When a failure has occurred to an active computer, the management computer sets the unique identification information which has been assigned to the Ethernet controller of the failed computer to the Ethernet controller of the standby computer and the standby computer boots up a software image for the failed computer by use of the unique identification information which has been set to its Ethernet controller by the management computer.

Abstract: To control the differentiation of mesenchymal stem cells into steroid hormone producing cells. Mesenchymal stem cells can be differentiated into steroid hormone-producing cells by being stimulated by a transcriptional factor (SF-1), preferably by the transcriptional factor (SF-1) and cAMP. The present invention is a method for differentiating mesenchymal stem cells into steroid hormone producing cells, comprising stimulating the mesenchymal stem cells by the transcriptional factor (SF-1). The mesenchymal stem cells may be further stimulated by cAMP.

Abstract: It is intended to provide a method of forming pancreatic ? cells from mesenchymal cells characterized by comprising using mammal-origin mesenchymal cells as starting cells, culturing these cells in the presence of, for example, a pancreatic ? cell-forming agent, and selecting and separating the thus obtained pancreatic ?cells with the use of a gene expressed specifically in such cells as a selection marker; a remedy for glucose intolerance which comprises pancreatic ? cells obtained by the above method as the active ingredient; a pancreatic ? cell-forming agent such as a cytokine to be used in the above method; a method of screening a candidate compound promoting the formation of pancreatic ? cells from mesenchymal cells; and a pancreatic ? cell formation promoter obtained by this screening method.

Abstract: This invention aims at providing a method of rapidly generating bone tissue having the mechanical strength, shape and size suitable for use in implantation, to provide the obtained normal regenerated bone tissue, and to provide a bone treatment material utilizing the same. Bone tissue suitable for implantation, having a specific shape and size is generated/regenerated by the proliferation of mesenchymal stem cells having the multi-potentiality for differentiation or osteoblasts in a fibrous and/or porous material which can serve as a scaffold for these cells.

Abstract: The present invention relates to methods for isolation, purification, expansion, and differentiation of cells having the potential to differentiate into cardiomyocytes. Furthermore, the present invention relates to methods for proliferating cells having the potential to differentiate into cardiomyocytes and for regulating their differentiation into cardiomyocytes using various cytokines and transcription factors. Moreover, the present invention relates to a method for obtaining surface antigens specific for cells having the potential to differentiate into cardiomyocytes, a method for obtaining genes encoding the surface antigens, a method for obtaining antibodies specific for the surface antigens, and a method for obtaining a protein and a gene controlling the proliferation of cells having the potential to differentiation into cardiomyocytes and their differentiation into cardiomyocytes.