Patents by Inventor Akiko Fujiwara
Akiko Fujiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11981325Abstract: A control device includes: a retry determination unit configured to determine whether to execute retry control based on a current position of a moving object and a target position when the moving object is moved to the target position by automatic steering; and a notification control unit configured to transmit a retry notification, including information indicating that the retry control is to be executed based on a determination result of the retry determination unit, to a terminal device. The notification control unit transmits the retry notification to the terminal device when the retry control, executed after at least a part of the moving object reaches the target position, is determined, and the notification control unit does not transmit the retry notification to the terminal device when the retry control, executed before at least a part of the moving object reaches the target position, is determined.Type: GrantFiled: December 21, 2022Date of Patent: May 14, 2024Assignee: HONDA MOTOR CO., LTD.Inventors: Tatsuro Fujiwara, Akiko Sato, Junpei Noguchi, Gaku Shimamoto, Takeshi Sasajima, Hiroki Takaku, Masafumi Sagara
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Patent number: 11938931Abstract: A stop assist system for moving a moving body to a stop position and making the moving body stop at the stop position includes: an external environment recognizing unit that recognizes an external environment of the moving body; and a moving body control unit that executes a driving process to make the moving body travel to the stop position based on a recognition result of the external environment recognizing unit. The moving body control unit suspends the driving process when, while the moving body is traveling to the stop position, the moving body control unit determines, based on the recognition result, that there is an object within a range of a prescribed lateral threshold value on a lateral outside of the moving body and the object extends over a prescribed longitudinal threshold value or more along a travel direction within the range.Type: GrantFiled: February 18, 2022Date of Patent: March 26, 2024Assignee: HONDA MOTOR CO., LTD.Inventors: Junpei Noguchi, Gaku Shimamoto, Takuma Sekino, Tatsuro Fujiwara, Akiko Nakamura, Kazuya Kobayashi, Masafumi Sagara, Takeshi Sasajima
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Patent number: 7903160Abstract: Disclosed herein is a data transfer circuit including, a plurality of data transfer lines, a plurality of data outputting sections, a plurality of data holding sections, a data-acquiring-clock supplying section a clock supplying section, and a column scan section.Type: GrantFiled: April 15, 2008Date of Patent: March 8, 2011Assignee: Sony CorporationInventors: Hiroyuki Taguchi, Hiroyuki Iwaki, Ken Koseki, Akiko Fujiwara, Hiroyuki Terakago, Kenichi Matsunaga, Yukio Fujita
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Publication number: 20080303931Abstract: Disclosed herein is a data transfer circuit including, a plurality of data transfer lines, a plurality of data outputting sections, a plurality of data holding sections, a data-acquiring-clock supplying section a clock supplying section, and a column scan section.Type: ApplicationFiled: April 15, 2008Publication date: December 11, 2008Inventors: Hiroyuki Taguchi, Hiroyuki Iwaki, Ken Koseki, Akiko Fujiwara, Hiroyuki Terakago, Kenichi Matsunaga, Yukio Fujita
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Patent number: 5541108Abstract: A process for producing 2-keto-L-gulonic acid which comprises converting L-sorbose and/or D-sorbitol into 2-keto-L-gulonic acid with the aid of a microorganism or its cell free extract, said microorganism belonging to the species Gluconobacter oxydans capable of producing 2-keto-L-gulonic acid and having L-sorbose dehydrogenase activity. Also disclosed are specific microorganisms useful in such process.Type: GrantFiled: June 28, 1994Date of Patent: July 30, 1996Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Teruhide Sugisawa, Masako Shinjoh, Yutaka Setoguchi, Tatsuo Hoshino
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Patent number: 5352599Abstract: A novel coenzyme independent L-sorbosone dehydrogenase originating from a microorganism belonging to the genus Gluconobacter oxydans which acts on L-sorbosone to produce 2-keto-L-gulonic acid.The enzyme has the following physico-chemical properties:a) optimum pH: about 7.0,b) optimum temperature: about 30.degree. C. to about 40.degree. C.,c) molecular sturucture: consisting of one type of unit having a molecular weight of about 47,500.+-.5,000 as measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis,d) thermostability: stable below 30.degree. C., ande) inhibition: by Cu.sup.2+ -ions.Type: GrantFiled: June 11, 1990Date of Patent: October 4, 1994Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Masako Shinjoh
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Patent number: 5085993Abstract: A coenzyme-independent L-sorbosone dehydrogenase has been prepared from a microorganism belong to the genus Pseudomonas, which acts on L-sorbosone to produce 2-keto-L-gulonic acid. The enzyme is membrane bound and has a molecular weight of about 47,000 kDa. The enzyme is used to carry out the conversion of L-sorbosone to 2-keto-L-gulonic acid.Type: GrantFiled: December 13, 1988Date of Patent: February 4, 1992Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino
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Patent number: 4916069Abstract: The present invention relates to novel coenyme independent L-sorbose dehydrogenase and a process for producing the same. The enzyme provided by the present invention catalyzes the oxidation of L-sorbose to L-sorbosone, the precursor of 2-keto-L-gulonic acid which is an important intermediate in the production of vitamin C.Due to the release duties in foreign countries, the original deposits with respect to the following strains have been transferred to the deposit under the Budapest Treaty at Agency of Industrial Science and Technology, Fermentation Research Institute, Japan on Jan. 29, 1987. And the following accession numbers have been allotted to each strain.______________________________________ strain Old No. New No. ______________________________________ Gluconobacter oxydans FERM-P No. 8422, Accession No. UV-10 FERM BP-1267 Gluconobacter oxydans E-1 FERM-P No. 8353, Accession No. FERM BP-1265 Gluconobacter oxydans H-2 FERM-P No. 8354, Accession No. FERM BP-1266 Gluconobacter oxydans L-8 FERM-P No.Type: GrantFiled: May 29, 1987Date of Patent: April 10, 1990Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Teruhide Sugisawa
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Patent number: 4902617Abstract: The present invention relates to novel enzyme having L-sorbosone dehydrogenase activity and a process for producing the same. This L-Sorbosone dehydrogenase enzyme provided by the present invention catalyzes the oxidation of L-sorbosone to 2-keto-L-gulonic acid in the presence of nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate as a coenzyme. 2-KGA is an important precursor for the production of vitamin C.Type: GrantFiled: May 29, 1987Date of Patent: February 20, 1990Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Teruhide Sugisawa
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Patent number: 4472571Abstract: There is presented the compounds 4-deoxy-aclacinomycin A and B and pharmaceutical preparations containing the same. The preparations are effective against bacteria and tumours. Also presented is a process for the preparation of optically active anthracycline glycosides A and B with the 7S-configuration starting from racemic anthracyclinones.Type: GrantFiled: June 30, 1983Date of Patent: September 18, 1984Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino
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Patent number: 4405713Abstract: There is presented the compounds 4-deoxy-aclacinomycin A and B and pharmaceutical preparations containing the same. The preparations are effective against bacteria and tumours. Also presented is a process for the preparation of optically active anthracycline glycosides A and B with the 7S-configuration starting from racemic anthracyclinones.Type: GrantFiled: December 28, 1981Date of Patent: September 20, 1983Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino
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Patent number: 4401812Abstract: The present invention is concerned with novel anthracyclines which are compounds of the general formula, ##STR1## wherein R.sub.1 is a methyl or acetonyl group and R.sub.2 is selected from the group consisting of ##STR2## Also presented is a method of making the above compounds. The compounds possess antibacterial and antitumor activities.Type: GrantFiled: October 2, 1981Date of Patent: August 30, 1983Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Masaaki Tazoe
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Patent number: 4383037Abstract: There is presented a process for producing anthracycline glycosides A by converting the sugar moiety of anthracycline glycosides B, represented by the following formula: ##STR1## into the sugar moiety of anthracycline glycosides A, represented by the following formula: ##STR2## with the aid of a microorganism belonging to the species Streptomyces galilaeus or Streptomyces melanogenes.Type: GrantFiled: October 19, 1981Date of Patent: May 10, 1983Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Yuzuru Sekine
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Patent number: 4379842Abstract: The invention relates to a process for producing 1.alpha.-hydroxydehydroepiandrosterone by fermenting or reacting dehydroepiandrosterone or a derivative thereof with microorganisms of the species Penicillium oxalicum or Aspergillus terreus or mycelium or extracts therefrom obtained when the microorganisms are in a stationary phase of growth. The invention process produces steroid compounds which are pharmacologically valuable substances.Type: GrantFiled: August 24, 1981Date of Patent: April 12, 1983Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Chikara Miyamoto, Toru Okuda
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Patent number: 4375511Abstract: The present invention relates to a process for producing aclacinomycins A and B. More particularly, the present invention is concerned with a process for producing selectively aclacinomycins A and B in high yield without formation of cinerubins A and B, by means of a fermentation process, utilizing Streptomyces galilaeus OBB-731.Type: GrantFiled: October 22, 1981Date of Patent: March 1, 1983Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Masaaki Tazoe
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Patent number: 4336332Abstract: The invention relates to a process for producing 7.sub..alpha. -hydroxylated steroids by fermenting or reacting a steroid to be hydroxylated with microorganisms of the genus Botryodiplodia or enzyme extracts thereof until hydroxylation occurs. The invention process produces steroid compounds which are pharmacologically valuable substances.Type: GrantFiled: February 4, 1980Date of Patent: June 22, 1982Assignee: Hoffmann-La Roche, Inc.Inventors: Mitsuhiko Fujiwara, Akiko Fujiwara, Chikara Miyamoto
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Patent number: 4329339Abstract: There is disclosed compounds of the formula ##STR1## wherein R.sup.1 represents a methyl or acetonyl group and R.sup.2 represents a hydrogen atom, a hydroxyl group or a group of the formula ##STR2## and a process for the preparation thereof. The compounds are useful as intermediates for the preparation of anthracycline antibiotics and certain of the compounds exhibit per se activity as antibacterial and antitumor agents.Type: GrantFiled: May 21, 1980Date of Patent: May 11, 1982Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Tatsuo Hoshino, Masaaki Tazoe
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Patent number: 4304861Abstract: A novel antibiotic having the ascribed formula ##STR1## is provided. They physical characteristics are as follows: (a) Elementary analysis: Calculated (for C.sub.20 H.sub.16 O.sub.7): C,65.22; H,4.35%. Found: C,64.60; H,4.34%.(b) Molecular weight (mass-spectrometric): 368.(c) Melting point: 225.degree.-226.degree. C.(d) Specific rotation: [.alpha.].sub.D .sup.20 =+123.5.degree. (c=0.2 in chloroform).(e) Ultraviolet absorption spectrum:.lambda..sub.max .sup.methanol =235 nm (.epsilon.=28600); 262 nm (.epsilon.=21900); 434-435 nm (.epsilon.=11300);.lambda..sub.max .sup.0.1-N NaOH/methanol =246 nm (.epsilon.=22400); 256 nm (.epsilon.=23200); 523-524 nm (.epsilon.=9600).(f) Infrared absorption spectrum: 3500, 1710, 1672, 1628, 1600, 1575, 1472, 1452, 1420, 1390, 1295, 1255, 1218, 1200, 1182, 1105, 1025, 1005, 962, 938, 848, 765, 752, 730 cm.sup.-1.Type: GrantFiled: November 8, 1979Date of Patent: December 8, 1981Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Mitsuhiko Fujiwara, Tatsuo Hoshino, Yuzuru Sekine, Masaaki Tazoe
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Patent number: 4271268Abstract: The preparation of D-arabitol by a fermentative process utilizing a micro-organism of the species Pichia haplophila or mutants thereof in a nutrient medium containing as a carbon source a hydrocarbon or ethyl alcohol is disclosed.Type: GrantFiled: September 8, 1978Date of Patent: June 2, 1981Assignee: Hoffmann-La Roche Inc.Inventors: Akiko Fujiwara, Setsuko Masuda
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Patent number: 4220716Abstract: A fermentation process for the preparation of 7.alpha.-hydroxylated steroids utilizing strains of the genus Mucor is disclosed. The 7.alpha.-hydroxylated steroids are useful intermediates for the synthesis of chenodeoxycholic acid as well as steroidal hormones.Type: GrantFiled: September 5, 1978Date of Patent: September 2, 1980Assignee: Hoffmann-La Roche Inc.Inventors: Mitsuhiko Fujiwara, Akiko Fujiwara, Chikara Miyamoto