Abstract: A micro electro mechanical systems (MEMS) control circuit includes a memory and a processor coupled to the memory and the processor configured to obtain an amplitude mean value of a monitor signal representing an amplitude in a direction of a horizontal axis of an MEMS device every unit time, compare the amplitude mean value with a reference value, and change a driving frequency of the MEMS device in a case where identical comparison results last consecutively a predetermined number of times.

Abstract: A drive circuit for supplying a drive current to light emitting elements includes an output circuit that sets a magnitude of the drive current based on an assumed value of a threshold current being a threshold value of the drive current, an acquisition circuit that acquires an optical-output monitor value indicating a magnitude of an optical output of the light emitting elements, a first calculation circuit that calculates an average value of the drive current in a predetermined period in a frame period as an average drive current value for each of the predetermined period, a second calculation circuit that calculates an average value of the optical-output monitor values in the predetermined period as an average optical-output monitor value, and an adjustment circuit that adjusts the assumed value of the threshold current value based on the average drive current value and the average optical-output monitor value.

Abstract: A drive circuit for supplying a drive current to light emitting elements includes an output circuit that sets a magnitude of the drive current based on an assumed value of a threshold current being a threshold value of the drive current, an acquisition circuit that acquires an optical-output monitor value indicating a magnitude of an optical output of the light emitting elements, a first calculation circuit that calculates an average value of the drive current in a predetermined period in a frame period as an average drive current value for each of the predetermined period, a second calculation circuit that calculates an average value of the optical-output monitor values in the predetermined period as an average optical-output monitor value, and an adjustment circuit that adjusts the assumed value of the threshold current value based on the average drive current value and the average optical-output monitor value.

Abstract: An optical transmitter includes a signal-processing circuit configured to perform signal processing on a first transmission signal and output a second transmission signal; an optical modulator configured to modulate input light with the second transmission signal and to output an optical signal; and a control circuit configured to output a control signal for controlling a carrier frequency of the optical signal to the signal-processing circuit, wherein the signal-processing circuit includes a map-adjustment circuit configured to adjust, based on the control signal and a modulation format, a map position of the second transmission signal onto a complex plane, and a phase-rotation circuit configured to apply, on the complex plane, rotation of a phase of the carrier frequency corresponding to the control signal to the second transmission signal at the adjusted map position.

Abstract: An optical transmitter includes a signal-process circuit to process a transmission signal; an optical modulator to modulate light input by the transmission signal output from the signal-process circuit, and output an optical signal; and a control circuit to output a control signal for controlling a carrier frequency of the optical signal, to the signal-process circuit, wherein the signal-process circuit comprises a phase-rotation circuit to apply phase rotation of the carrier frequency on a complex plane according to the control signal, to the transmission signal, a map-adjustment circuit to determine scale factor for a map according to an angle of the phase rotation, and a modulation-format-map circuit to map the transmission signal on the complex plane based on a modulation format and the scale factor, wherein the phase-rotation circuit is configured to rotate, on the complex plane, the phase of the carrier frequency mapped based on the scale factor.

Abstract: A non-transitory computer-readable recording medium stores a state machine dividing program that causes a computer to execute a process including: determining whether a design value based on circuit information that indicates a circuit that controls a computation process by using a state machine is greater than a predetermined reference value; and dividing, when the design value is greater than the reference value, the state machine into a plurality of state machines.

Abstract: A non-transitory computer-readable recording medium stores a state machine dividing program that causes a computer to execute a process including: determining whether a design value based on circuit information that indicates a circuit that controls a computation process by using a state machine is greater than a predetermined reference value; and dividing, when the design value is greater than the reference value, the state machine into a plurality of state machines.

Abstract: A calculation method executed by a computer, the calculation method includes calculating, using a processor, a length of one side of a second module based on an area of the second module that is included in a first module in a circuit and includes devices; and calculating, using the processor, a length of a wiring of the first module based on the calculated length and the number of fan-outs of the first module.

Abstract: An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (hereinafter, referred to as “ASCT2”) or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of ASCT2 and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.

Abstract: The present invention provides a monoclonal antibody which specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to its extracellular region, or a method for using the same. The present invention can provide a monoclonal antibody or an antibody fragment thereof, which specifically recognizes a polypeptide encoded by CD27 gene containing an O-linked sugar chain to which galactose is not bound, and binds to its extracellular region; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which comprises the DNA; a transformant obtainable by transforming the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a diagnostic agent or a therapeutic agent comprising the antibody or the antibody fragment thereof as an active ingredient.

Abstract: An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (hereinafter, referred to as “ASCT2”) or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of ASCT2 and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.

Abstract: A wiring inspection apparatus includes a first calculating unit, a second calculating unit, and an output unit. The first calculating unit calculates the number of components arranged along two sides, one of which extends in a first direction and the other one of which extends in a second direction, of a minimum rectangle including a transmission component and a reception component. The second calculating unit calculates the number of the components arranged along the two sides at a predetermined arrangement density of relay components. When the number of the relay components is greater than the number of the components calculated by the second calculating unit, the output unit outputs information indicating the presence of a wiring extending in a direction opposite to a direction from the transmission component to the reception component among wirings connecting the transmission component, the reception component, and the relay components.

Abstract: A wiring inspection apparatus includes a dividing unit, a calculating unit, and an output unit. The dividing unit draws a boundary line in a predetermined area between a transmission component and a reception component, to divide the predetermined area into a first area containing the transmission component and a second area containing the reception component. The transmission component transmits a signal to the reception component via relay components. The calculating unit calculates a number of wirings that connect the components across the boundary line, based on positions of the transmission component, the reception component, and the relay components in the predetermined area. The output unit outputs information indicating the presence of a wiring extending in a direction opposite to a direction from the transmission component to the reception component, when the number of the wirings calculated by the calculating unit is equal to or greater than a predetermined value.

Abstract: A wiring inspection apparatus includes a dividing unit, a calculating unit, and an output unit. The dividing unit draws a boundary line in a predetermined area between a transmission component and a reception component, to divide the predetermined area into a first area containing the transmission component and a second area containing the reception component. The transmission component transmits a signal to the reception component via relay components. The calculating unit calculates a number of wirings that connect the components across the boundary line, based on positions of the transmission component, the reception component, and the relay components in the predetermined area. The output unit outputs information indicating the presence of a wiring extending in a direction opposite to a direction from the transmission component to the reception component, when the number of the wirings calculated by the calculating unit is equal to or greater than a predetermined value.

Abstract: A wiring inspection apparatus includes a first calculating unit, a second calculating unit, and an output unit. The first calculating unit calculates the number of components arranged along two sides, one of which extends in a first direction and the other one of which extends in a second direction, of a minimum rectangle including a transmission component and a reception component. The second calculating unit calculates the number of the components arranged along the two sides at a predetermined arrangement density of relay components. When the number of the relay components is greater than the number of the components calculated by the second calculating unit, the output unit outputs information indicating the presence of a wiring extending in a direction opposite to a direction from the transmission component to the reception component among wirings connecting the transmission component, the reception component, and the relay components.

Abstract: The present invention provides a method for screening a patient to be administered with a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient, said method comprising collecting samples from patients who expresses an antigen which is recognized by the anti-cancer antibody, measuring cadherin function in the samples, and selecting a patient whose the cadherin function is decreased or deleted; a method for screening a patient who has a high efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient; and a method for improving an efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient.

Abstract: A recombinant antibody or the antibody fragment thereof which specifically reacts with an extracellular domain of human CCR4; a DNA which encodes the recombinant antibody or the antibody fragment thereof; a method for producing the recombinant antibody or the antibody fragment thereof; a method for immunologically detecting CCR4, a method for immunologically detecting a cell which expressed CCR4 on the cell surface, a method for depleting a cell which expresses CCR4 on the cell surface, and a method for inhibiting production of Th2 cytokine, which comprise using the recombinant antibody according or antibody fragment thereof; a therapeutic or diagnostic agent for Th2-mediated immune diseases; and a therapeutic or diagnostic agent for a blood cancer.

Abstract: Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a method for producing a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.

Abstract: A calculation method executed by a computer, the calculation method includes calculating, using a processor, a length of one side of a second module based on an area of the second module that is included in a first module in a circuit and includes devices; and calculating, using the processor, a length of a wiring of the first module based on the calculated length and the number of fan-outs of the first module.

Abstract: An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (hereinafter, referred to as “ASCT2”) or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of ASCT2 and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.