Patents by Inventor Akiko Futamura

Akiko Futamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN NTCP-BINDING ANTIBODY CAPABLE OF INHIBITING INFECTION OF HEPATITIS B VIRUS (HBV) TO HUMAN HEPATOCYTES
    Publication number: 20240092924
    Abstract: The present invention provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles. The present invention also provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles, the antibody having a reduced effect on bile acid transport by NTCP.
    Type: Application
    Filed: October 7, 2020
    Publication date: March 21, 2024
    Inventors: Toshitada TAKEMORI, Akiko SUGIMOTO, Michishige HARADA, Mikako SHIROUZU, Takehisa MATSUMOTO, Tomomi SOMEYA, Hiroyuki OSADA, Yushi FUTAMURA, Kunitada SHIMOTOHNO, Hironori NISHITSUJI, Kazuaki CHAYAMA, Daiki MIKI
  • COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN
    Publication number: 20180261331
    Abstract: Some embodiments include a computer-assisted method of biomedical treatment design. For example, a computer system can select a compound model associated with a candidate compound that is structured to bind to a biological target to modulate the biological target into achieving a therapeutic effect. The computer system can then identify a structural feature in the compound model as a hinge region that connects domains in the candidate compound. The computer system then determines a mutation process to introduce a mutation at the hinge region such that the mutation activates the candidate compound. The computer system then generates an updated compound model based on the mutation added to the candidate compound to present in a treatment design interface.
    Type: Application
    Filed: May 14, 2018
    Publication date: September 13, 2018
    Inventor: Akiko Futamura
  • COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN
    Publication number: 20150142408
    Abstract: Some embodiments include a computer-assisted method of biomedical treatment design. For example, a computer system can select a compound model associated with a candidate compound that is structured to bind to a biological target to modulate the biological target into achieving a therapeutic effect. The computer system can then identify a structural feature in the compound model as a hinge region that connects domains in the candidate compound. The computer system then determines a mutation process to introduce a mutation at the hinge region such that the mutation activates the candidate compound. The computer system then generates an updated compound model based on the mutation added to the candidate compound to present in a treatment design interface.
    Type: Application
    Filed: November 17, 2014
    Publication date: May 21, 2015
    Inventor: Akiko Futamura