Patents by Inventor Akiko Oguni

Akiko Oguni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-DR5 antibodies, polynucleotides and methods
    Patent number: 9856321
    Abstract: The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: January 2, 2018
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Toshiaki Ohtsuka, Takeshi Takizawa, Akiko Oguni, Tatsuji Matsuoka, Hiroko Yoshida, Yumi Matsui
  • NOVEL ANTI-DR5 ANTIBODY
    Publication number: 20160068603
    Abstract: The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 10, 2016
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Toshiaki Ohtsuka, Takeshi Takizawa, Akiko Oguni, Tatsuji Matsuoka, Hiroko Yoshida, Yumi Matsui
  • Anti-DR5 antibodies, polynucleotides and methods
    Patent number: 9127070
    Abstract: The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 8, 2015
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Toshiaki Ohtsuka, Takeshi Takizawa, Akiko Oguni, Tatsuji Matsuoka, Hiroko Yoshida, Yumi Matsui
  • NOVEL ANTI-DR5 ANTIBODY
    Publication number: 20140004120
    Abstract: The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies.
    Type: Application
    Filed: October 27, 2011
    Publication date: January 2, 2014
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Toshiaki Ohtsuka, Takeshi Takizawa, Akiko Oguni, Tatsuji Matsuoka, Hiroko Yoshida, Yumi Matsui