Abstract: To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1? released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has an effect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.

Abstract: The present invention provides a therapeutic agent for failure-to-thrive or short stature which contains C-type natriuretic peptide (CNP) or a CNP derivative as an active ingredient, reduces adverse reactions, and exhibits excellent efficacy, and a method for treating failure-to-thrive or short stature.

Abstract: To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1? released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has an effect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.

Abstract: An ink curable with actinic energy rays characterized by containing a photocleavage type photopolymerization initiator (A) comprising ?-aminoalkylphenone compound (A1) having a molar absorption coefficient measured at a wavelength of 363 nm of 100 (l/mol·cm) or more and less than 100,000 (l/mol·cm) and/or an acylphosphine oxide compound (A2) having a molar absorption coefficient measured at a wavelength of 365 nm of 100 (l/mol·cm) or more and less than 100,000 (l/mol·cm); and a hydrogen abstraction type photopolymerization initiator (B) comprising 4,4?-dialkylaminobenzophenone having a molar absorption coefficient at a wavelength of 365 nm of 10,000 (l/mol·cm) or more and less than 1,000,000 (l/mol·cm) and by optionally containing a tertiary amine compound (C) having a molar extinction coefficient as measured at a wavelength of 365 nm of 1 (l/mol·cm) or lower. The ink further includes a resin, a pigment, and a compound having an acrylate group.

Abstract: An ink curable with actinic energy rays which is characterized by containing a photocleavage type photopolymerization initiator (A) comprising ?-aminoalkylphenone compound (A1) having a molar absorption coefficient as measured at a wavelength of 365 nm of 100 (l/mol·cm) or more and less than 100,000 (l/mol·cm) and/or an acylphosphine oxide compound (A2) having a molar absorption coefficient as measured at a wavelength of 365 nm of 100 (l/mol·cm) or more and less than 100,000 (l/mol·cm); and a hydrogen abstraction type photopolymerization initiator (B) comprising 4,4?-dialkylaminobenzophenone having a molar absorption coefficient at a wavelength of 365 nm of 10,000 (l/mol·cm) or more and less than 1,000,000 (l/mol·cm) and by optionally containing a tertiary amine compound (C) having a molar extinction coefficient as measured at a wavelength of 365 nm of 1 (l/mol·cm) or lower. The ink curable with actinic energy rays further includes a resin, a pigment, and a compound having an acrylate group.

Abstract: The image recording apparatus scans a heat mode recording material with a light beam modulated in accordance with image information, to thereby record an image on the heat mode recording material. The apparatus includes an unit for generating a modulated signal, an unit for generating an additional signal at a timing of at least one of rising and falling of the modulated signal and a unit for generating a drive signal by adding the additional signal to the modulated. The image forming method and apparatus scan a photosensitive material with the light beam to record an image, and a power of the light beam is set to a power of a level at which a recording line width or a recording dot size, which is determined depending upon a threshold value for the photosensitive material to blacken, is substantially fixed even if defocus occurs.

Abstract: The image recording apparatus scans a heat mode recording material with a light beam modulated in accordance with image information, to thereby record an image on the heat mode recording material. The apparatus includes an unit for generating a modulated signal, an unit for generating an additional signal at a timing of at least one of rising and falling of the modulated signal and a unit for generating a drive signal by adding the additional signal to the modulated. The image forming method and apparatus scan a photosensitive material with the light beam to record an image, and a power of the light beam is set to a power of a level at which a recording line width or a recording dot size, which is determined depending upon a threshold value for the photosensitive material to blacken, is substantially fixed even if defocus occurs.