Patents by Inventor Akiko Shima

Akiko Shima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9187450
    Abstract: The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: November 17, 2015
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Tsuyoshi Nakamura, Hidenori Namiki, Naoki Terasaka, Akiko Shima, Masahiko Hagihara, Noriaki Iwase, Katsunori Takata, Osamu Kikuchi, Kazunari Tsuboike, Hiroyuki Setoguchi, Kenji Yoneda, Hidetoshi Sunamoto, Koji Ito
  • Patent number: 8927157
    Abstract: Provided is a condensed polycyclic aromatic compound, having lithium ion responsivity and is suitable for lithium ion secondary battery applications, a production process thereof, a positive electrode active material containing that condensed polycyclic aromatic compound, and a positive electrode for a lithium ion secondary battery provided therewith, and further provided is a lithium ion secondary battery, having high capacity and cycling adaptability, that has the positive electrode as a constituent thereof. The condensed polycyclic aromatic compound has at least four imino groups in a molecule thereof.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: January 6, 2015
    Assignees: Kabushiki Kaisha Toyota Jidoshokki, Keio University
    Inventors: Osamu Ohmori, Akiko Shima, Hitotoshi Murase, Masataka Nakanishi, Junichi Niwa, Kimihisa Yamamoto
  • Publication number: 20140213549
    Abstract: The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
    Type: Application
    Filed: July 8, 2011
    Publication date: July 31, 2014
    Applicants: UBE INDUSTRIES, LTD., DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tsuyoshi Nakamura, Hidenori Namiki, Naoki Terasaka, Akiko Shima, Masahiko Hagihara, Noriaki Iwase, Katsunori Takata, Osamu Kikuchi, Kazunari Tsuboike, Hiroyuki Setoguchi, Kenji Yoneda, Hidetoshi Sunamoto, Koji Ito
  • Publication number: 20140005143
    Abstract: The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 2, 2014
    Applicants: Daiichi Sankyo Company, Limited, Ube Industries, Ltd.
    Inventors: Tsuyoshi Nakamura, Hidenori Namiki, Naoki Terasaka, Akiko Shima, Masahiko Hagihara, Noriaki Iwase, Katsunori Takata, Osamu Kikuchi, Kazunari Tsuboike, Hiroyuki Setoguchi, Kenji Yoneda, Hidetoshi Sunamoto, Koji Ito
  • Publication number: 20130109653
    Abstract: The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
    Type: Application
    Filed: July 8, 2011
    Publication date: May 2, 2013
    Applicants: UBE INDUSTRIES, LTD., DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tsuyoshi Nakamura, Hidenori Namiki, Naoki Terasaka, Akiko Shima, Masahiko Hagihara, Noriaki Iwase, Katsunori Takata, Osamu Kikuchi, Kazunari Tsuboike, Hiroyuki Setoguchi, Kenji Yoneda, Hidetoshi Sunamoto, Koji Ito
  • Publication number: 20130078514
    Abstract: Provided is a condensed polycyclic aromatic compound, having superior lithium ion responsivity and is suitable for lithium ion secondary battery applications, a production process thereof, a positive electrode active material containing that condensed polycyclic aromatic compound, and a positive electrode for a lithium ion secondary battery provided therewith, and further provided is a lithium ion secondary battery, having high capacity and superior cycling adaptability, that has the positive electrode as a constituent thereof. The condensed polycyclic aromatic compound according to the present invention has at least four imino groups in a molecule thereof.
    Type: Application
    Filed: May 26, 2011
    Publication date: March 28, 2013
    Applicants: KEIO UNIVERSITY, KABUSHIKI KAISHA TOYOTA JIDOSHOKKI
    Inventors: Osamu Ohmori, Akiko Shima, Hitotoshi Murase, Masataka Nakanishi, Junichi Niwa, Kimihisa Yamamoto
  • Patent number: 7598393
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein A, B, R1, R2 and R3 are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: October 6, 2009
    Assignee: Pfizer Inc.
    Inventors: Kana Kon-I, Miyako Matsumizu, Akiko Shima
  • Publication number: 20060094750
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein A, B, R1, R2 and R3 are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis, cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asthma,
    Type: Application
    Filed: November 2, 2005
    Publication date: May 4, 2006
    Inventors: Kana Kon-I, Miyako Matsumizu, Akiko Shima