Patents by Inventor Akila Subasinghe

Akila Subasinghe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Centromere detector and method for determining radiation exposure from chromosome abnormalities
    Patent number: 8605981
    Abstract: A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum width or intensity or width and intensity; counting the number of centromeres in each chromosome in each cell; computing the frequency of dicentric chromosomes in a population of cells; and determining the radiation dose by comparing the computed frequency of dicentric chromosomes with a previously determined dose-response curve from a calibrated source.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: December 10, 2013
    Assignee: Cytognomix Inc.
    Inventors: Peter Keith Rogan, Joan Helen Knoll, Jagath Samarabandu, Akila Subasinghe
  • Centromere Detector and Method for Determining Radiation Exposure From Chromosome Abnormalities
    Publication number: 20130216118
    Abstract: A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum width or intensity or width and intensity; counting the number of centromeres in each chromosome in each cell; computing the frequency of dicentric chromosomes in a population of cells; and determining the radiation dose by comparing the computed frequency of dicentric chromosomes with a previously determined dose-response curve from a calibrated source.
    Type: Application
    Filed: November 4, 2011
    Publication date: August 22, 2013
    Inventors: Peter Keith Rogan, Joan Helen Knoll, Jagath Samarabandu, Akila Subasinghe