Abstract: A connection type fluid transfer and treatment system apparatus and method for efficiently and continuously executing transfer and treatment of small or micro amounts of sample solutions without substantial transfer loss, which includes a first microsolution reaction microtube having one open end and a second closed end, a second microsolution target microtube having substantially the same shape as the first microtube also having one open end and one closed end, and a connector for connecting together the open ends of the first microtube to the open end of the second tube. The connector includes a foramenous membrane support, which removably receives chemically or biologically treated membranes for applying a predetermined treatment to a solution while passing the sample solution from the first microtube to the second tube. Alternately, a "single use only" connector having disposed therein a membrane pretreated with a quantitative amount of reagent may be used for certain treatment operations.