Patents by Inventor Akinleye Alabi

Akinleye Alabi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence-defined polymers and methods of making same and using same
    Patent number: 11384205
    Abstract: Methods of making sequence-defined polymers and sequence-defined polymers. The methods are based on the orthogonal reactivity of monomers having at least two different functional groups. The sequence-defined polymers can be used in various applications. For example, the SDPs (e.g., pH sensitive SDPs) are used in cell lysis methods or as molecular vehicles to transport drug cargo into cells.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: July 12, 2022
    Assignee: CORNELL UNIVERSITY
    Inventors: Christopher Akinleye Alabi, Mintu Porel
  • SYSTEMS AND METHODS FOR INTRACELLULAR DELIVERY VIA NON-CHARGED SEQUENCE-DEFINED CELL-PENETRATING OLIGOMERS
    Publication number: 20210308270
    Abstract: The present disclosure provides oligoTEAs and methods of using the oligoTEAs. The oligoTEAs may be functionalized with one or more cargo group. The oligoTEAs may be made by iterative thiol-ene and Michael reactions. The oligoTEAs functionalized with one or more cargo group may be used to treat bacterial infections, cancers, viral infections, urinary tract infections, skin infections, cystic fibrosis, sepsis, fungal infections, or a combination thereof.
    Type: Application
    Filed: May 16, 2019
    Publication date: October 7, 2021
    Inventors: Christopher Akinleye ALABI, Ngoc Nhu PHAN
  • OLIGOTHIOETHERAMIDES (OLIGOTEAS) AS ANTI-MICROBIAL AND ANTI-BACTERIAL AGENTS
    Publication number: 20200361861
    Abstract: Provided are oligothioetheramides (oligoTEAs) having a plurality of cationic groups, such as, for examples, cationic groups having guanidinium groups. The cationic oligoTEAs exhibit activity against gram-positive and gram-negative bacteria. The compounds can be used as antibacterial compounds against the same.
    Type: Application
    Filed: August 17, 2018
    Publication date: November 19, 2020
    Inventors: Christopher Akinleye ALABI, Ngoc Nhu PHAN
  • SEQUENCE-DEFINED POLYMERS AND METHODS OF MAKING SAME AND USING SAME
    Publication number: 20200299461
    Abstract: Methods of making sequence-defined polymers and sequence-defined polymers. The methods are based on the orthogonal reactivity of monomers having at least two different functional groups. The sequence-defined polymers can be used in various applications. For example, the SDPs (e.g., pH sensitive SDPs) are used in cell lysis methods or as molecular vehicles to transport drug cargo into cells.
    Type: Application
    Filed: December 10, 2019
    Publication date: September 24, 2020
    Inventors: Christopher Akinleye Alabi, Mintu Porel
  • Sequence-defined polymers and methods of making same and using same
    Patent number: 10501581
    Abstract: Methods of making sequence-defined polymers and sequence-defined polymers. The methods are based on the orthogonal reactivity of monomers having at least two different functional groups. The sequence-defined polymers can be used in various applications. For example, the SDPs (e.g., pH sensitive SDPs) are used in cell lysis methods or as molecular vehicles to transport drug cargo into cells.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: December 10, 2019
    Assignee: Cornell University
    Inventors: Christopher Akinleye Alabi, Mintu Porel
  • Carrier Nanoparticles And Related Compositions, Methods And Systems
    Publication number: 20190314520
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 17, 2019
    Inventors: Mark E. Davis, Akinleye Alabi
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 10342879
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: July 9, 2019
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • Carrier Nanoparticles And Related Compositions, Methods And Systems
    Publication number: 20190000990
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Mark E. Davis, Akinleye Alabi
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 10155051
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: December 18, 2018
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20180169265
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 21, 2018
    Inventors: MARK E. DAVIS, AKINLEYE ALABI
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 9913911
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: March 13, 2018
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 9610355
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: April 4, 2017
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20170080099
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 23, 2017
    Inventors: MARK E. DAVIS, AKINLEYE ALABI
  • CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20160228566
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 11, 2016
    Inventors: MARK E. DAVIS, AKINLEYE ALABI
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 9334367
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: May 10, 2016
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • SEQUENCE-DEFINED POLYMERS AND METHODS OF MAKING SAME AND USING SAME
    Publication number: 20160075831
    Abstract: Methods of making sequence-defined polymers and sequence-defined polymers. The methods are based on the orthogonal reactivity of monomers having at least two different functional groups. The sequence-defined polymers can be used in various applications. For example, the SDPs (e.g., pH sensitive SDPs) are used in cell lysis methods or as molecular vehicles to transport drug cargo into cells.
    Type: Application
    Filed: August 19, 2015
    Publication date: March 17, 2016
    Inventors: Christopher Akinleye Alabi, Mintu Porel
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 9186327
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: November 17, 2015
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20150322207
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 12, 2015
    Inventors: MARK E. DAVIS, AKINLEYE ALABI
  • Carrier nanoparticles and related compositions, methods and systems
    Patent number: 8968714
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: March 3, 2015
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Akinleye Alabi
  • CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20150031832
    Abstract: Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
    Type: Application
    Filed: October 8, 2014
    Publication date: January 29, 2015
    Inventors: MARK E. DAVIS, AKINLEYE ALABI