Patents by Inventor Akinobu Kishi
Akinobu Kishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9757332Abstract: This invention relates to a gel-like composition in which ubiquinol is dispersed and stabilized in a gel and which contains 0.2 to 5% by weight of ubiquinol, 5 to 15% by weight of gelatin, 55 to 80% by weight of carbohydrate and/or water-soluble dietary fiber, and 9 to 18% by weight of water, and further contains ascorbic acid and/or gallate type catechin.Type: GrantFiled: April 30, 2014Date of Patent: September 12, 2017Assignee: UHA MIKAKUTO CO., LTD.Inventors: Shinsuke Kitanaka, Yoshimi Haza, Satoshi Doi, Yasuhiro Shinka, Nobuya Sato, Akinobu Kishi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20160346171Abstract: There are provided an oral composition and a confection that exhibit activity equivalent to or higher than that of a decanoic acid-containing composition, and a method for producing such an oral composition. The oral composition and the confection contain at least three ingredients: cinnamon, low molecular proanthocyanidin, and menthol. The method for producing, the oral composition includes the steps of: dissolving at least 0.2 to 1.0% by weight of low molecular proanthocyanidin in 0.2 to 2.0% by weight of at least one water-soluble solvent selected from glycerin or propylene glycol to form a solution; kneading at least 0.1 to 0.5% by weight of cinnamon and 0.1 to 0.4% by weight of menthol into sugar-free base dough to prepare candy- or gel-like kneaded dough; and mixing the solution with the kneaded dough.Type: ApplicationFiled: May 28, 2015Publication date: December 1, 2016Inventors: Shigeru Abe, Kazumi Hayama, Miki Takahashi, Motofumi Suzuki, Akinobu Kishi, Nobuya Sato, Taiji Matsukawa, Yasumasa Yamada, Ichiro Yamada, Kazuhisa Maeda
-
Patent number: 9340477Abstract: A process for producing a hydroxystilbene derivative represented by formula (1) (wherein X1-X4 independently represent a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, or a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms; Z1 and Z2 independently represent a hydrogen atom, or a group represented by the formula (2) (wherein X5 and X6 independently represent a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, or a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms); and Z1 and Z2 may be the same as or different from each other; wherein X1-X6 may be the same as or different from one another), which is characterized by heating a 4-hydroxycinnamic acid compound and a hydroxystilbene compound in the presence of a metal salt.Type: GrantFiled: November 25, 2011Date of Patent: May 17, 2016Assignee: UHA MIKAKUTO CO., LTD.Inventors: Akinobu Kishi, Satoshi Doi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20160089332Abstract: This invention relates to a gel-like composition in which ubiquinol is dispersed and stabilized in a gel and which contains 0.2 to 5% by weight of ubiquinol, 5 to 15% by weight of gelatin, 55 to 80% by weight of carbohydrate and/or water-soluble dietary fiber, and 9 to 18% by weight of water, and further contains ascorbic acid and/or gallate type catechin.Type: ApplicationFiled: April 30, 2014Publication date: March 31, 2016Applicant: UHA Mikakuto Co., Ltd.Inventors: Shinsuke KITANAKA, Yoshimi HAZA, Satoshi DOI, Yasuhiro SHINKA, Nobuya SATO, Akinobu KISHI, Taiji MATSUKAWA, Takeki MATSUI, Yasumasa YAMADA, Ichiro YAMADA
-
Publication number: 20160053227Abstract: This invention relates to an agent for inducing differentiation of white adipocytes into brown-like adipocytes comprising a compound which is a cyclization reaction product of a hydroxystilbene and which is represented by Formula (1): (wherein each of R1 to R8 is a hydrogen atom, a hydroxyl group, a saturated or unsaturated, straight or branched alkoxy group having 1 to 10 carbon atoms, or a saturated or unsaturated, straight or branched alkyl group having 1 to 10 carbon atoms, and R1 to R8 may be same or different), or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 27, 2014Publication date: February 25, 2016Applicant: UHA Mikakuto Co., Ltd.Inventors: Yasuhiro SHINKA, Akinobu KISHI, Taiji MATSUKAWA, Takeki MATSUI, Yasumasa YAMADA, Ichiro YAMADA
-
Publication number: 20150321985Abstract: Provided is an antifeeding agent including a (hydroxystilbene compound)-(sinapinic acid) reaction product represented by Formula (1) (in Formula (1), each of R1 to R4 is a hydrogen atom, a hydroxy group, a saturated or unsaturated, straight or branched chain alkoxy group having 1 to 10 carbon atoms, or a saturated or unsaturated, straight or branched chain alkyl group having 1 to 10 carbon atoms; and R1 to R4 are optionally the same as or different from each other) or a pharmaceutically acceptable salt thereof. The antifeeding agent is a novel, safe, highly practical antifeeding agent that can be taken for a long period of time.Type: ApplicationFiled: December 20, 2013Publication date: November 12, 2015Inventors: Satoshi DOI, Akinobu KISHI, Taiji MATSUKAWA, Takeki MATSUI, Yasumasa YAMADA, Ichiro YAMADA, Kazutoshi SAYAMA
-
Patent number: 9051245Abstract: This invention relates to a resveratrol polymerization compound represented by Formula (1) (in which, in Formula (1), R1 and R2 represent —OH or Formula (2) and R1 and R2 are not the same) or a pharmaceutically acceptable salt thereof and an anticancer agent, an anticancer agent for oral cancer, an antioxidant, an antibacterial agent, a lipase inhibitor, an antiobesity agent, a therapeutic agent for skin diseases, a food, a pharmaceutical agent, a quasi drug, or a cosmetic containing one or more compounds selected from the group consisting of the resveratrol polymerization compound and the pharmaceutically acceptable salt thereof.Type: GrantFiled: October 27, 2011Date of Patent: June 9, 2015Assignee: UHA MIKAKUTO CO., LTD.Inventors: Akinobu Kishi, Satoshi Doi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Patent number: 8987522Abstract: A differentiation inducer to brown-like adipocytes of white adipocytes containing a novel compound having an excellent differentiation induction action to brown-like adipocytes of white adipocytes as compared with resveratrol. A differentiation inducer to brown-like adipocytes of white adipocytes which is a reaction product of hydroxystilbenes and sinapic acid and contains a compound represented by Formula (1) or a pharmacologically permissible salt thereof: in which, in Formula (1), R1 to R4 represents a hydrogen atom, a hydroxy group, a saturated or unsaturated, linear or branched alkoxy group having 1 to 10 carbon atoms, or a saturated or unsaturated, linear or branched alkyl group having 1 to 10 carbon atoms and R1 to R4 each may be the same or different.Type: GrantFiled: December 17, 2013Date of Patent: March 24, 2015Assignee: Uha Mikakuto Co., Ltd.Inventors: Yasuhiro Shinka, Akinobu Kishi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20140288334Abstract: This invention relates to a resveratrol polymerization compound represented by Formula (1) (in which, in Formula (1), R1 and R2 represent —OH or Formula (2) and R1 and R2 are not the same) or a pharmaceutically acceptable salt thereof and an anticancer agent, an anticancer agent for oral cancer, an antioxidant, an antibacterial agent, a lipase inhibitor, an antiobesity agent, a therapeutic agent for skin diseases, a food, a pharmaceutical agent, a quasi drug, or a cosmetic containing one or more compounds selected from the group consisting of the resveratrol polymerization compound and the pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 27, 2011Publication date: September 25, 2014Applicant: UHA MIKAKUTO CO., LTD.Inventors: Akinobu Kishi, Satoshi Doi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20140171690Abstract: To provide a differentiation inducer to brown-like adipocytes of white adipocytes containing a novel compound having an excellent differentiation induction action to brown-like adipocytes of white adipocytes as compared with resveratrol. A differentiation inducer to brown-like adipocytes of white adipocytes which is a reaction product of hydroxystilbenes and sinapic acid and contains a compound represented by Formula (1) or a pharmacologically permissible salt thereof: [Chemical Formula 1] in which, in Formula (1), R1 to R4 represents a hydrogen atom, a hydroxy group, a saturated or unsaturated, linear or branched alkoxy group having 1 to 10 carbon atoms, or a saturated or unsaturated, linear or branched alkyl group having 1 to 10 carbon atoms and R1 to R4 each may be the same or different.Type: ApplicationFiled: December 17, 2013Publication date: June 19, 2014Applicant: UHA MIKAKUTO CO., LTD.Inventors: Yasuhiro SHINKA, Akinobu KISHI, Taiji MATSUKAWA, Takeki MATSUI, Yasumasa YAMADA, Ichiro YAMADA
-
Publication number: 20140127382Abstract: A drink contains (a) gallate-type catechin, (b) collagen having an average molecular weight of 4000 or more, and (c) at least one thickening and stabilizing agent selected from water-soluble soy fiber, gum arabic, pectin, carrageenan, tamarind seed gum, psyllium seed gum, ghatti gum, alginic acid and a salt thereof, polyglutamic acid and a salt thereof, and carboxymethylcellulose, in which the contents (Unit: wt %) [A], [B], and [C] of the components (a), (b), and (c) are in the ranges satisfying the following expressions; i) 0.06?[A]?0.6; 3.0?([B]/[A])?20.0; and ([C]/[A])?0.4.Type: ApplicationFiled: June 18, 2012Publication date: May 8, 2014Applicant: UHA Mikakuto Co., Ltd.Inventors: Shinsuke Kitanaka, Yoshimi Haza, Nobuya Sato, Akinobu Kishi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20130310611Abstract: A process for producing a phenolic polymerizable compound represented by formula (1) or (2); wherein X1-X9 independently represent a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, or a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms; Y represents a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms, or a group represented by formula (6); and Z represents a hydrogen atom or a group represented by formula (3), which is characterized by heating a 4-hydroxycinnamic acid compound in the presence of a metal salt.Type: ApplicationFiled: October 27, 2011Publication date: November 21, 2013Applicant: UHA MIKAKUTO CO., LTD.Inventors: Akinobu Kishi, Satoshi Doi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20130296613Abstract: A process for producing a hydroxystilbene derivative represented by formula (1) (wherein X1-X4 independently represent a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, or a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms; Z1 and Z2 independently represent a hydrogen atom, or a group represented by the formula (2) (wherein X5 and X6 independently represent a hydrogen atom, a hydroxy group, a saturated or unsaturated linear or branched alkoxy group having 1-10 carbon atoms, or a saturated or unsaturated linear or branched alkyl group having 1-10 carbon atoms); and Z1 and Z2 may be the same as or different from each other; wherein X1-X6 may be the same as or different from one another), which is characterized by heating a 4-hydroxycinnamic acid compound and a hydroxystilbene compound in the presence of a metal salt.Type: ApplicationFiled: November 25, 2011Publication date: November 7, 2013Applicant: UHA MIKAKUTO CO., LTD.Inventors: Akinobu Kishi, Satoshi Doi, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada
-
Publication number: 20110009616Abstract: The invention provides antiarterioscierosis agents containing as the active ingredient porphyrin derivatives or ester derivatives thereof as represented by the general formula (1) or (2); and foods or pharmaceutical compositions containing the agents. The porphyrin derivatives and the ester derivatives thereof exhibit an effect of inhibiting the bonding of oxidized LDL to LOX-1 expressed in vascular endothelial cells, macrophage an so on and an antagonistic effect of inhibiting the incorporation of oxidized LDL into cells through LOX-1, and are highly safe.Type: ApplicationFiled: June 29, 2007Publication date: January 13, 2011Inventors: Akinobu Kishi, Koji Yuasa, Taiji Matsukawa, Takeki Matsui, Yasumasa Yamada, Ichiro Yamada