Patents by Inventor Akio Hyodo

Akio Hyodo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cephem compound, process for producing the compound, and antimicrobial composition containing the same
    Patent number: 5698544
    Abstract: The present invention provides a cephem compound having a high antimicrobial activity against various pathogenic bacteria.The cephem compound of the invention is represented by the formula ##STR1## wherein Q represents CH or N, R.sup.1 represents a carboxylate or the like, R.sup.2 represents a hydrogen atom, and R represents ##STR2## wherein R.sup.3 represents a group --(CH.sub.2).sub.m --Y (wherein m is an integer of 1 to 5, and Y represents a quaternary ammonium group) or the like, n is an integer of 0 to 4, B.sup.- represents an anion, f is 0 or 1 when R.sup.1 represents a carboxylate, and 2 when R.sup.1 represents a carboxyl group, and the ring C represents a 5-membered heterocyclic group of not more than 4 nitrogen atoms, which may be substituted by a lower alkyl group.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: December 16, 1997
    Assignees: Otsuka Kagaku Kabushiki Kaisha, Taiho Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Akagi, Masaru Yasui, Takae Yamada, Masahiro Ito, Akio Hyodo, Hideaki Hanaki
  • Penam sulfones as .beta.-lactamase inhibitors
    Patent number: 5686441
    Abstract: Novel 3-(substituted)-3-methyl-4-thia-1-azabicyclo?3.2.0!heptane-2-carboxylate, 4,4-dioxides which are of value for use in combination with .beta.-lactam antibiotics to increase the effectiveness of the antibiotics.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: November 11, 1997
    Assignees: Syphar Laboratories, Inc., Taiho Pharmaceutical Co., Ltd.
    Inventors: Samarendra Nath Maiti, Oludotun Adebayo Phillips, Andhe Venkat Narender Reddy, Eduardo Luis Setti, Ronald George Micetich, Chieko Kunugita, Fusahiro Higashitani, Akio Hyodo
  • Cephem compound and pharmaceutical composition containing the compound
    Patent number: 5635500
    Abstract: The object of the present invention is to provide a cephem compound having high activity against various pathogenic microorganisms. The cephem compound of this invention is represented by the general formula ##STR1## wherein Q represents CH or N; R.sup.1 represents a carboxylate etc; and R represents ##STR2## or the group ##STR3## where R.sup.2 represents a lower alkyl group etc, n represents an integer of 0 or 1 through 3, B.sup.- represents an anion, f is equal to 0 when R.sup.1 represents a carboxylate and 1 where R.sup.1 represents a carboxyl group, and the ring C represents a 5-membered heterocyclic group of not more than 4 nitrogen atoms, which may be substituted by lower alkyls.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: June 3, 1997
    Assignees: Otsuka Kagaku Kabushiki Kaisha, Taiho Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Akagi, Masaru Yasui, Yoshifumi Hara, Hideaki Hanaki, Akio Hyodo