Patents by Inventor Akio Imai

Akio Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230288382
    Abstract: An inspection apparatus comprises a first channel that passes an aqueous sample therethrough, a second channel that passes a phosphate eluent therethrough, a separation device that separates by size a group of substances contained in the aqueous sample, and a TOC device that oxidizes each substance separated by the separation device by size and measures organic carbon contained in each substance. The separation device includes a column for size-exclusion chromatography and a sample injection unit that introduces the aqueous sample into a mobile phase passed through the first channel. The second channel is connected to the first channel between the column and the sample injection unit, and causes the phosphate eluent to merge with the aqueous sample between the sample injection unit and the column.
    Type: Application
    Filed: July 15, 2021
    Publication date: September 14, 2023
    Applicant: SHIMADZU CORPORATION
    Inventors: Akio IMAI, Takayuki SATO
  • Publication number: 20230273169
    Abstract: An object is to increase an efficiency of removing carbon dioxide derived from inorganic carbon. An inspection apparatus includes: a column that separates a group of substances contained in an aqueous sample by size; an addition unit that adds a reagent, which acidifies the aqueous sample, into a channel; a degassing unit provided downstream of the addition unit for degassing carbon dioxide; a measurement unit that measures organic carbon contained in each substance from which the carbon dioxide has been removed; and a temperature maintaining unit that maintains a temperature of each of the column and a container in which a gas-permeable tube of the degassing unit is housed.
    Type: Application
    Filed: July 15, 2021
    Publication date: August 31, 2023
    Applicant: SHIMADZU CORPORATION
    Inventors: Akio IMAI, Koichi SHIMOTORI, Akioki NAKAMORI, Kiyuki NOTO
  • Patent number: 11396832
    Abstract: A valve timing adjusting device includes an intake variable valve mechanism and an exhaust variable valve mechanism. The exhaust variable valve mechanism includes an exhaust electric driving portion and an exhaust phase shifting portion including an input shaft. The exhaust phase shifting portion is disposed in a rotation transmission path between an exhaust camshaft and a crankshaft and configured to shift a rotation phase of the exhaust camshaft. The input shaft rotates in a rotational direction opposite to a rotational direction of the crankshaft when advancing the rotation phase. A phase of the exhaust phase shifting portion is configured to be shifted to a most advanced angle phase when the exhaust electric driving portion is de-energized or fails and when the exhaust phase shifting portion receives a torque in a forward rotational direction.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: July 26, 2022
    Assignee: DENSO CORPORATION
    Inventors: Kazuaki Nemoto, Akio Imai
  • Patent number: 11225619
    Abstract: An aviation biofuel component including 90.0 vol % or more of isoparaffins of C10 to C12 and 30.0 vol % or more of isoparaffins which are at least C10 or C12.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: January 18, 2022
    Assignee: IDEMITSU KOSAN CO., LTD.
    Inventors: Yasuyo Saito, Akio Imai, Mitsuru Koike, Hiroyuki Tooi
  • Publication number: 20210222593
    Abstract: A valve timing adjusting device includes an intake variable valve mechanism and an exhaust variable valve mechanism. The exhaust variable valve mechanism includes an exhaust electric driving portion and an exhaust phase shifting portion including an input shaft. The exhaust phase shifting portion is disposed in a rotation transmission path between an exhaust camshaft and a crankshaft and configured to shift a rotation phase of the exhaust camshaft. The input shaft rotates in a rotational direction opposite to a rotational direction of the crankshaft when advancing the rotation phase. A phase of the exhaust phase shifting portion is configured to be shifted to a most advanced angle phase when the exhaust electric driving portion is de-energized or fails and when the exhaust phase shifting portion receives a torque in a forward rotational direction.
    Type: Application
    Filed: April 9, 2021
    Publication date: July 22, 2021
    Inventors: Kazuaki NEMOTO, Akio IMAI
  • Publication number: 20210189268
    Abstract: An aviation biofuel component including 90.0 vol % or more of isoparaffins of C10 to C12 and 30.0 vol % or more of isoparaffins which are at least C10 or C12.
    Type: Application
    Filed: October 10, 2018
    Publication date: June 24, 2021
    Applicant: IDEMITSU KOSAN CO., LTD.
    Inventors: Yasuyo SAITO, Akio IMAI, Mitsuru KOIKE, Hiroyuki TOOI
  • Patent number: 10968408
    Abstract: It is an object of the present invention to provide a gasoline composition utilizing lignocellulosic biomass, which is a plant-derived resource that does not cause competition with food production, the gasoline composition satisfying properties required for use in gasoline engines, and a process for producing the gasoline composition. The gasoline composition contains 0.3 to 10.0 vol % of hemicellulose-derived pentene.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: April 6, 2021
    Assignee: IDEMITSU KOSAN CO., LTD
    Inventors: Yasuyo Okuyama, Akio Imai, Mitsuru Koike, Shinya Sasaki
  • Publication number: 20190225899
    Abstract: It is an object of the present invention to provide a gasoline composition utilizing lignocellulosic biomass, which is a plant-derived resource that does not cause competition with food production, the gasoline composition satisfying properties required for use in gasoline engines, and a process for producing the gasoline composition. The gasoline composition contains 0.3 to 10.0 vol % of hemicellulose-derived pentene.
    Type: Application
    Filed: July 24, 2017
    Publication date: July 25, 2019
    Inventors: Yasuyo Okuyama, Akio Imai, Mitsuru Koike, Shinya Sasaki
  • Publication number: 20120146438
    Abstract: To provide an electromagnetic brake and an electric motor in which, in the case of using the motor with its shaft thereof in a vertical position, static friction torque and dynamic friction torque caused by electromagnetic brake portions is reduced, thereby enabling to provide reliable motor torque on the motor output shaft, and stable braking.
    Type: Application
    Filed: June 20, 2011
    Publication date: June 14, 2012
    Applicant: Hitachi Industrial Equipment Systems Co., LTD.
    Inventors: Hitoshi IDE, Akio Imai, Hidekazu Matsui
  • Patent number: 8127729
    Abstract: A driven-side rotator is rotatable synchronously with a camshaft and is supported between a gear member and a sprocket member of the driving-side rotator in an axial direction. A stopper portion of the driven-side rotator is adapted to contact the driving-side rotator in a rotational direction to limit a change in a relative phase between the crankshaft and the camshaft. The stopper portion radially outwardly projects from a small diameter portion provided at one end part of the driven-side rotator. A large diameter portion is provided at the other end part of the driven-side rotator and has a radial size that is measured from a rotational axis to a radially outer peripheral surface of the large diameter portion and is equal to or larger than that of the stopper portion.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: March 6, 2012
    Assignee: Denso Corporation
    Inventors: Hiroki Takahashi, Akio Imai
  • Publication number: 20110105759
    Abstract: It is intended to provide a process for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-ylidene]methylpiperidine represented by the structural formula (I): (I) which is useful as an intermediate material for a pharmaceutical or a solvate thereof in which impurity content is further reduced and operation is simple and suitable for industrial production by reacting 5,6-dimethoxy-1-indanone with 1-benzyl-4-formylpiperidine in a reaction solvent in the presence of a base and then gradually crystallizing a target substance in a reaction mixture in a high temperature region.
    Type: Application
    Filed: July 24, 2006
    Publication date: May 5, 2011
    Inventors: Akio Imai, Akihiko Shimotani, Tomio Tsurugi, Yukio Narabu
  • Publication number: 20100288216
    Abstract: A driven-side rotator is rotatable synchronously with a camshaft and is supported between a gear member and a sprocket member of the driving-side rotator in an axial direction. A stopper portion of the driven-side rotator is adapted to contact the driving-side rotator in a rotational direction to limit a change in a relative phase between the crankshaft and the camshaft. The stopper portion radially outwardly projects from a small diameter portion provided at one end part of the driven-side rotator. A large diameter portion is provided at the other end part of the driven-side rotator and has a radial size that is measured from a rotational axis to a radially outer peripheral surface of the large diameter portion and is equal to or larger than that of the stopper portion.
    Type: Application
    Filed: May 17, 2010
    Publication date: November 18, 2010
    Applicant: DENSO CORPORATION
    Inventors: Hiroki TAKAHASHI, Akio IMAI
  • Patent number: 7828232
    Abstract: A fuel injection valve includes a valve body having a valve seat, a nozzle plate arranged on an injection side of the valve body, a valve plug for intermitting fuel injection through the nozzle hole, and a sleeve. The nozzle plate has a nozzle hole through which fuel is injected from the injection side of the valve body. The sleeve makes contact with an end surface of the nozzle plate on an opposite side of the valve body with respect to the nozzle plate to partially cover the nozzle plate. Fuel is injected to an outside of the sleeve through the nozzle hole of the nozzle plate and an opening of the sleeve. The end surface of the nozzle plate makes contact with the sleeve in a contact portion. The contact portion has at least one groove that extends from the opening outwardly with respect to a substantially radial direction of the sleeve.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: November 9, 2010
    Assignee: Denso Corporation
    Inventors: Ryutaro Oomori, Akio Imai, Tetsuharu Matsuo
  • Patent number: 7795438
    Abstract: Processes for preparing 1-benzyl-4-[(5,6-dimethoxy-lindanon)-2-yl]methylpiperidine (donepezil), which is useful as an intermediate for medicines, and for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (donepezil hydrochloride), which is useful as a medicine. The process for donepezil hydrochloride production comprises catalytically hydrogenating the compound represented by the structural formula (III) [1-benzyl-4-[(5,6-dimethoxy-lindanon)-2-ylidene]methylpiperidine] with a Raney nickel catalyst under mild conditions and subsequently treating it with hydrochloric acid. Thus, impurities are further diminished. The operations are simple and the process is suitable for industrial production.
    Type: Grant
    Filed: April 27, 2005
    Date of Patent: September 14, 2010
    Assignee: Eisai R&D Management Co., Ltd
    Inventors: Akio Imai, Hiroshi Nishimura
  • Publication number: 20090199801
    Abstract: A valve timing adjusting apparatus includes a driving-side rotor, a driven-side rotor, a sun gear, and a planet gear. The driving-side rotor is rotatable synchronously with the crankshaft. The driven-side rotor is received in the driving-side rotor and rotatable synchronously with a camshaft. The sun gear is rotatable integrally with the driving-side rotor. The planet gear moves epicyclically relative to the sun gear. The driving-side rotor includes a peripheral wall member and a bottom wall member. One of the sun gear and the bottom wall member is fitted with an inner peripheral side of one axial end portion of the peripheral wall member. The other one is fitted with an outer peripheral side of the other axial end portion of the peripheral wall member.
    Type: Application
    Filed: February 9, 2009
    Publication date: August 13, 2009
    Applicant: DENSO CORPORATION
    Inventors: Akio Imai, Yasushi Morii
  • Publication number: 20090171094
    Abstract: 1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine p-toluenesulfonate or a solvate thereof.
    Type: Application
    Filed: July 12, 2006
    Publication date: July 2, 2009
    Inventors: Kazuhide Ashizawa, Akio Imai
  • Patent number: 7479563
    Abstract: The present invention provides a simple method of producing polymorphic crystal (III), which has high safety to environment and the bodies of operators; is gentle to environment; and can produce at low costs; and has a high refining effect. It is a method of producing polymorphic crystal (III) of donepezil hydrochloride (chemical name: 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine•monohydrochloride) represented by the following structural formula (formula (I)), which comprises dissolving donepezil (chemical name: 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) in ethanol; and adding hydrochloric acid or hydrogen chloride thereto, followed by stirring.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: January 20, 2009
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Akio Imai, Akihiko Shimotani
  • Publication number: 20080306272
    Abstract: A compound represented by the following formula (1): wherein R represents a 4-fluorophenyl group and the like; Q represents —CH(CH3)— and the like; and n represents 1 and the like and a pharmaceutically acceptable salt thereof can be prepared in one-pot by reacting a compound represented by the following formula (2): wherein R1 represents a 4-fluorophenyl group and the like; and Q and n have the same meaning as described above, with 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde in the presence of a base and, if necessary, removing a protecting group.
    Type: Application
    Filed: May 15, 2008
    Publication date: December 11, 2008
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Naoyuki Shimomura, Seiji Yoshikawa, Yoshihiko Hisatake, Akio Imai
  • Publication number: 20080234485
    Abstract: 1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrobromide or a solvate thereof.
    Type: Application
    Filed: February 1, 2007
    Publication date: September 25, 2008
    Inventors: Kazuhide Ashizawa, Takashi Hasebe, Akio Imai
  • Patent number: 7332606
    Abstract: 1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine or hydrochloride thereof, which is useful as a drug, can be produced in high purity by safer and easier operations suitable for industrial production by subjecting 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-ylidene]methyl-piperidine or a solvate thereof to catalytic hydrogenation in the presence of a palladium-alumina catalyst and if necessary, converting the thus obtained compound to its hydrochloride.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: February 19, 2008
    Assignee: Eisai R&D Management Co., Ltd.
    Inventor: Akio Imai