Patents by Inventor Akio Kakefuda

Akio Kakefuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof
    Publication number: 20060122170
    Abstract: A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or a pharmaceutically acceptable salt thereof, which is useful as an agent for treating or preventing nocturia and/or diabetes insipidus, is provided.
    Type: Application
    Filed: April 26, 2004
    Publication date: June 8, 2006
    Applicant: ASTELLA PHARMA INC.
    Inventors: Hiroyuki Koshio, Issei Tsukamoto, Akio Kakefuda, Seijiro Akamatsu, Chikashi Saitoh
  • 1,4,5.6-tetrahydroimidazo[4,5-d]diazepine derivatives or salts thereof
    Patent number: 7056910
    Abstract: To provide a compound having a superior arginine vasopressin antagonism. A novel 1,4,5,6-tetrahydroimidazo[4,5-d]benzazepine derivative or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: June 6, 2006
    Assignee: Astellas Pharma Inc.
    Inventors: Hiroyuki Koshio, Akio Kakefuda, Ippei Sato, Ryutaro Wakayama, Masanao Sanagi
  • Novel denzamide derivatives and process for production thereof
    Publication number: 20060084807
    Abstract: There are provided a novel process for the production of an isoquinoline derivative having an inhibitory action for If current; a novel benzamide derivative or a salt thereof used for the production process; and a process for the production of the benzamide derivative or a salt thereof.
    Type: Application
    Filed: December 24, 2003
    Publication date: April 20, 2006
    Inventors: Shinya Yoshida, Toshihiro Watanabe, Kiyotaka Marumo, Akio Kakefuda
  • 1,4,5,6-Tetrahydroimidazo[4,5-d]diazepine derivatives or salts thereof
    Publication number: 20040034012
    Abstract: To provide a compound having a superior arginine vasopressin antagonism. A novel 1,4,5,6-tetrahydroimidazo[4,5-d]benzazepine derivative or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 27, 2003
    Publication date: February 19, 2004
    Inventors: Hiroyuki Koshio, Akio Kakefuda, Ippei Sato, Ryutaro Wakayama, Masanao Sanagi
  • Isoquinoline derivatives or salts thereof
    Patent number: 6573279
    Abstract: The compound of the present invention relates to a drug, particularly to a novel isoquinoline derivative or its salt having an If current inhibitory effect without serious side effects such as convulsion and also to a drug, particularly a cardiac rate lowering agent, containing the compound as the active ingredient. Namely, the compound has a current If inhibitory effect and is particularly useful as a cardiac rate lowering agent for preventing ischemic heart diseases such as angina and cardiac infarction and circulatory diseases such as congestive cardiac insufficiency and arrhythmia (supraventricular arrhythmia). The present invention relates to dialkoxy-1,2,3,4-tetrahydroquinoline-2-carbonylpiperidino-3,4-dialkoxypropaneanilide derivatives, etc.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: June 3, 2003
    Inventors: Toshihiro Watanabe, Akio Kakefuda, Toshio Okazaki, Noriyuki Masuda, Koichi Wada