Abstract: [Problem] A compound which is useful as a STING inhibitor is provided. [Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.

Abstract: This ink-jet ink (hereinafter, referred to as “ink”) comprises an aqueous solvent, a pigment, and a thixotropic agent, and is characterized by having a viscosity at 25° C. of 15 mPa·s or lower at a shear rate of 1,000 (1/s) and having a viscosity at 25° C. of 150 mPa·s or higher at a shear rate of 1 (1/s) in a state in which the aqueous solvent has been removed therefrom so that the mass of the ink is 80% of the initial mass.

Abstract: A liquid pressurizing apparatus, comprises a tank provided on a device installation surface for storing liquid so that a fluid level is located above the device installation surface; and a vertical pump including a suction port connected to the tank, multi-stage impellers arranged in a vertical direction, and a discharge port for discharging the liquid passing through the multi-stage impellers. The multi-stage impellers include a first stage impeller positioned at the lowest part of the multi-stage impellers and being configured such that the liquid from the suction port flows into the first stage impeller. The first stage impeller is disposed below the device installation surface.

Abstract: A liquid pressurizing apparatus, comprises a tank provided on a device installation surface for storing liquid so that a fluid level is located above the device installation surface; and a vertical pump including a suction port connected to the tank, multi-stage impellers arranged in a vertical direction, and a discharge port for discharging the liquid passing through the multi-stage impellers. The multi-stage impellers include a first stage impeller positioned at the lowest part of the multi-stage impellers and being configured such that the liquid from the suction port flows into the first stage impeller. The first stage impeller is disposed below the device installation surface.

Abstract: A vertical pump includes: a rotary shaft; multi-stage impellers; a casing accommodating the multi-stage impellers; a mechanical seal provided in a penetration part of the casing for the rotary shaft; a balance sleeve, the balance sleeve being positioned between a final stage impeller of the multi-stage impellers and the mechanical seal in the penetration part for the rotary shaft; an intermediate chamber provided between the rotary shaft and the casing and provided on an opposite side of the multi-stage impellers across the balance sleeve in an axial direction of the rotary shaft, the intermediate chamber communicating with an intermediate stage impeller among the multi-stage impellers; a low pressure chamber provided between the rotary shaft and the casing, the low pressure chamber communicating with a low pressure side compared to the intermediate chamber; and a partition wall part dividing the intermediate chamber and the low pressure chamber.

Abstract: A vertical pump includes: a rotary shaft; multi-stage impellers; a casing accommodating the multi-stage impellers; a mechanical seal provided in a penetration part of the casing for the rotary shaft; a balance sleeve, the balance sleeve being positioned between a final stage impeller of the multi-stage impellers and the mechanical seal in the penetration part for the rotary shaft; an intermediate chamber provided between the rotary shaft and the casing and provided on an opposite side of the multi-stage impellers across the balance sleeve in an axial direction of the rotary shaft, the intermediate chamber communicating with an intermediate stage impeller among the multi-stage impellers; a low pressure chamber provided between the rotary shaft and the casing, the low pressure chamber communicating with a low pressure side compared to the intermediate chamber; and a partition wall part dividing the intermediate chamber and the low pressure chamber.

Abstract: An inkjet recording method comprising: shooting to a recording medium an active-light-ray-curable inkjet ink including a photopolymerizable compound, a wax, a photopolymerization initiator, and a coloring material, and that undergoes reversible sol-gel phase transition relative to temperature; and curing the ink by irradiating an active light ray to the ink that has been shot to the recording medium, wherein the ink including a (meta) acrylate compound (B) having a molecular weight of 300-1500 and a ClogP value within the range 4.0 to 7.0, the wax content being 1.0-10 percent by mass of the total mass of the ink, and the temperature of the recording medium at active light ray irradiation being set such that the saturation solubility of the wax with respect to the ink constitutes 0.5 percent by mass or less. According to this image-forming method, blooming is suppressed.

Abstract: An active ray-curable inkjet ink which contains a photocurable compound, a photopolymerization initiator, a gelling agent and a non-polymerizable liquid compound that is in a liquid state at 25° C., with the liquid compound being contained in an amount of 15-50% by mass relative to the mass of the ink. Since droplets of this active ray-curable inkjet ink are prevented from combining with each other after landing, this active ray-curable inkjet ink is capable of providing high quality images. Meanwhile, the surface gloss of printed images is increased, and printed images having less coating film thickness difference (namely, less relief-like texture) can be formed.

Abstract: The purpose of the present invention is to provide: an active ray-curable inkjet ink which has good dispersion stability during storage, good surface smoothness when ejected on a recording medium, and does not undergo the bleeding of a fatty acid onto the surface of the ink; and an image formation method using the active ray-curable inkjet ink. The purpose can be achieved by an active ray-curable inkjet ink which contains: a photopolymerizable compound; at least one wax in the total mass of 1 to 8 mass % relative to the whole mass of the ink; and a fatty acid in the total mass of 0.0001 to 0.10 mass % relative to the whole mass of the wax.

Abstract: In the present invention, provided are an ink-jet image forming method employing actinic energy radiation curable ink-jet ink exhibiting no offset resistance during storage by superposing printed portions after printing in addition to excellent properties of printing durability, gloss evenness of coated paper and paper-feeding suitability, and an ink-jet ink set thereof. It is a feature that the ink-jet image forming method possessing the steps of providing colorless ink on a substrate, followed by heating the colorless ink provided on the substrate, and subsequently exposing the colorless ink provided on the substrate, to actinic energy radiation, wherein the colorless ink contains no colorant but an actinic energy radiation curable composition and a gelling agent with which a thermoreversible gel is formed.

Abstract: The purpose of the present invention is to provide an actinic ray curable inkjet ink which, in an inkjet printing method, is capable of having both high pinning characteristics and high ejection characteristics. In order to achieve the above purpose, this actinic ray curable inkjet ink includes an actinic ray curable compound, ketone wax, and ester wax, and reversibly goes through a sol-gel phase transition depending on the temperature.

Abstract: The purpose of the present invention is to provide: an active ray-curable inkjet ink which has good dispersion stability during storage, good surface smoothness when ejected on a recording medium, and does not undergo the bleeding of a fatty acid onto the surface of the ink; and an image formation method using the active ray-curable inkjet ink. The purpose can be achieved by an active ray-curable inkjet ink which contains: a photopolymerizable compound; at least one wax in the total mass of 1 to 8 mass % relative to the whole mass of the ink; and a fatty acid in the total mass of 0.0001 to 0.10 mass % relative to the whole mass of the wax.

Abstract: An active ray-curable inkjet ink which contains a photocurable compound, a photopolymerization initiator, a gelling agent and a non-polymerizable liquid compound that is in a liquid state at 25° C., with the liquid compound being contained in an amount of 15-50% by mass relative to the mass of the ink. Since droplets of this active ray-curable inkjet ink are prevented from combining with each other after landing, this active ray-curable inkjet ink is capable of providing high quality images. Meanwhile, the surface gloss of printed images is increased, and printed images having less coating film thickness difference (namely, less relief-like texture) can be formed.

Abstract: An inkjet ink set comprising: a color ink including a photocurable compound, a photopolymerization initiator, a gelling agent, and a colorant, the color ink undergoing a sol-gel phase transition depending on the temperature; and a clear ink including a photocurable compound, a photopolymerization initiator, and a gelling agent, the clear ink undergoing a sol-gel phase transition depending on the temperature. The viscosity (?) (CL) of the clear ink at 25° C. is less than ½ the viscosity (?) (CO) of the color ink at 25° C., and the viscosity (?) (CL) of the clear ink is 1×103 mPa·s or greater. Provided is an inkjet ink set by which a printed image offering both high image quality and surface gloss can be formed.

Abstract: Provided are an actinic energy radiation curable ink, which can achieve a high fineness and natural glossiness when recording is carried out onto a non-absorptive recording medium such as a film or a laminated paper or a slightly absorptive recording medium such as a coated paper; and an actinic energy radiation curable inkjet recording method. This actinic energy radiation curable ink, which is to be used in inkjet recording, is characterized by: said actinic energy radiation curable ink undergoing reversible sol/gel phase transition depending on temperature; said actinic energy radiation curable ink containing from 1% or more by mass to less than 10% by mass of a gelling agent; and, at temperature Tm (° C.) that is separately defined, the storage elastic modulus (G?) of the actinic energy radiation curable ink being from 0.1 or more Pa to less than 1000 Pa and the storage elastic modulus (G?) being smaller than the loss elastic modulus (G?) thereof.

Abstract: An inkjet ink set comprising: a color ink including a photocurable compound, a photopolymerization initiator, a gelling agent, and a colorant, the color ink undergoing a sol-gel phase transition depending on the temperature; and a clear ink including a photocurable compound, a photopolymerization initiator, and a gelling agent, the clear ink undergoing a sol-gel phase transition depending on the temperature. The viscosity (?) (CL) of the clear ink at 25° C. is less than ½ the viscosity (?) (CO) of the color ink at 25° C., and the viscosity (?) (CL) of the clear ink is 1×103 mPa·s or greater. Provided is an inkjet ink set by which a printed image offering both high image quality and surface gloss can be formed.

Abstract: An inkjet recording method comprising: shooting to a recording medium an active-light-ray-curable inkjet ink including a photopolymerizable compound, a wax, a photopolymerization initiator, and a coloring material, and that undergoes reversible sol-gel phase transition relative to temperature; and curing the ink by irradiating an active light ray to the ink that has been shot to the recording medium, wherein the ink including a (meta) acrylate compound (B) having a molecular weight of 300-1500 and a C log P value within the range 4.0 to 7.0, the wax content being 1.0-10 percent by mass of the total mass of the ink, and the temperature of the recording medium at active light ray irradiation being set such that the saturation solubility of the wax with respect to the ink constitutes 0.5 percent by mass or less. According to this image-forming method, blooming is suppressed.

Abstract: Disclosed is an actinic energy radiation curable inkjet ink which can be printed on various types of recording media, has excellent printed image quality and excellent fixability particularly on coated printing paper, and is improved in storage stability and ejection stability. Also disclosed is an inkjet recording method using the actinic energy radiation curable inkjet ink. The actinic energy radiation curable inkjet ink is characterized by containing a compound represented by Formula (1) or a compound represented by Formula (2) in an amount of not less than 0.1% by mass and less than 20% by mass based on a total mass of the ink.

Abstract: The active ray-curable inkjet ink comprises a gelling agent, photopolymerizable compounds and a photoinitiator, and reversibly transitions into a sol-gel phase according to the temperature. Therein: (1) a (meth)acrylate compound having a molecular weight of 300-1,500 and having 3-14 (—CH2—CH2—O—) structural units within a molecule is included as the first photopolymerizable compound at a proportion of 30-70 mass % relative to the total mass of the ink; (2) a (meth)acrylate compound having a molecular weight of 300-1,500 and a C log P value of 4.0-7.0 is included as the second photopolymerizable compound at a proportion of 10-40 mass % relative to the total mass of the ink; and (3) the gelling agent has a total of at least 12 carbon atoms, and has a straight or branched alkyl chain including at least three carbon atoms.

Abstract: An inkjet recording device includes an image forming drum, a recording medium supplying section, a recording head which ejects ink onto a recording medium, a first heating unit which heats the recording medium held on the drum before image recording, a second heating unit which heats the drum downstream of the position at which the recording medium is outputted after image recording and upstream of the supplying section, a heating-unit temperature detector, a drum temperature detector, and a heating control section. The heating control section performs heat control of the first heating unit such that the temperature detected by the heating-unit temperature detector falls within a predetermined set temperature range, and performs heat control of the second heating unit such that the temperature detected by the drum temperature detector falls within a predetermined set temperature range.