Abstract: In an embodiment, an object of the present invention is to provide a double-stranded nucleic acid complex having a novel structure. In an embodiment, the present invention relates to a nucleic acid complex comprising a first nucleic acid strand and a second nucleic acid strand, wherein said first nucleic acid strand: (1) is capable of hybridizing to at least a part of a target transcriptional product; (2) has an antisense effect on the target transcriptional product; and (3) is a gapmer comprising a central region, and a 5? wing region and a 3? wing region, said second nucleic acid strand comprises at least one sugar-unmodified central region (first exposed region) consisting of one sugar-unmodified ribonucleoside or two or three contiguous sugar-unmodified ribonucleosides linked by an internucleoside bond, which is or are complementary to a part of said first nucleic acid strand, and said first nucleic acid strand is annealed to said second nucleic acid strand.

Abstract: A detection device includes a plurality of optical sensors arranged in a detection area, a light source configured to emit light that is emitted to an object to be detected and is detected by the optical sensors, and a processor configured to perform processing based on outputs from the optical sensors. The processor is configured to determine, based on the outputs of the respective optical sensors obtained at a cycle of a predetermined period, an optical sensor an output of which is to be employed from among the optical sensors.

Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.

Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.

Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.

Abstract: There are provided an antidesiccant containing a nucleic acid as an active ingredient which codes for a heat shock protein originating from a salt tolerant cyanobacteria, an antidesiccant containing a nucleic acid which codes for a protein selected from a protein/enzyme relating to a photonic synthesis control, a protein/enzyme controlling the size of a plant body, a protein/enzyme promoting extension of a root, a protein/enzyme promoting growth of a plant body, and a protein/enzyme improving the stability of an RNA, or containing the antisense sequence thereof, a method of using the antidesiccant for making photonic synthesis more efficient, and a transpiration suppression method for a plant.

Abstract: The present invention is relative to a system enabling a through operation between a mileage system and an electronic money system. The mileage system is such a system in which mile points as distance points corresponding to the flight distance of an aircraft are accumulated and exchanged for boarding tickets and other services. An IC card (230) having stored a wallet number in it is used. The wallet number and a mileage number are managed in a correlated fashion. Responsively to a request from a user, reference is made to an electronic money value ledger (222), matched to the wallet number, while reference is also made to a mile point ledger (122), matched to the mileage number. A preset number of the mile points are changed over to an electronic money value and, depending on changed-over results, the electronic money value ledger is subjected to integration processing, while the mile point ledger is subjected to deduction processing.

Abstract: A surge absorber utilizes a varistor electrically connected to a surge absorbing element. The varistor voltage and nonlinearity factor are chosen so that the varistor has a preselected voltage-current characteristic which prevents the varistor from breaking down and short circuiting and resulting in a thermal runaway.

Abstract: A protection circuit for a semiconductor circuit for protecting it from a thunder surge and overcurrent or overvoltage. A surge absorbing element and a Zenor diode are in parallel connected to the semiconductor circuit. A first fuse are connected before between the electric source and the surge absorbing element. A second fuse and a resistor, which is in series connection, is arranged between the surge absorbing element and the Zenor diode.

Abstract: A sheet type large display unit includes a thin, flexible back sheet which is capable of being rolled up, the flexible back sheet having a plurality of electrical connections formed thereon in rows and columns; a plurality of display dot devices mounted on the front surface of the back sheet in a matrix arrangement, each display dot device including four light emitting diodes mounted on a printed circuit board substrate and connected with the electrical connections; a thin, flexible transparent display sheet which is capable of being rolled up, the display sheet being in covering relation to the display dot devices; and an adhesive which secures the peripheral edge of the display sheet in sealing relation to the peripheral edge of the back sheet.

Abstract: The present invention provides a light-emitting diode lamp having a printed circuit board which is arranged inside a glass bulb having a base at an end thereof, via a stem and stays. A plurality of light-emitting diodes are mounted on the printed circuit board, a current being supplied to the light-emitting diodes through a series resistor. The series resistor has an annular shape and is fitted around the stem, so that a conventional lower-voltage LED lamp can be upgraded to a 100-V LED lamp.

Abstract: In a high pressure discharge lamp device provided with an inductive stabilizer and a starting circuit consisting of a serial circuit of a resistor and a bimetal switch, a pulse waveform conversion circuit is arranged therein to reduce the pulse peak of the starting voltage and also broaden the pulse width of the starting voltage. The pulse waveform conversion circuit comprises a serial circuit of a resistor and a switching element, such as micro-gap element, which operates at a voltage lower than the starting voltage of the discharge lamp but higher than the secondary load-free voltage of the stabilizer.

Abstract: A novel gap type surge absorber. The surge absorber comprises a plurality of conductive ceramic thin films formed on the surface of a molded insulating body and separated from each other by an extremely narrow gap, electrodes composed of a metallic material fixed to both ends of the plural conductive ceramic thin films and an inert gas sealed between the electrodes. The surge absorber is based on a two-stage discharge mechanism consisting of a discharge due to electrons emitted between the conductive ceramic thin films when a surge voltage is applied to the electrodes and a following creeping discharge generated between the electrodes. The surge absorber has a prolonged life and a good annealing characteristic as well as a very small discharge lag and a small electrostatic capacity and is excellent in cutting off a follow current.

Abstract: A novel gap type surge absorber is disclosed. The surge absorber comprises a plurality of carbon thin films isolated from each others at short distances attached to the surface of an insulating body and one material selected from the group consisting of a metal, an alloy and a conductive adhesive as an electrode fixed to each of the plural carbon thin films. The surge absorber is an element based on a new mechanism that when a surge voltage reaches a prescribed value, a discharge is generated owing to emission of electrons between the carbon thin films and thereby a creeping discharge is initiated between the electrodes. The surge absorber has a small electrostatic capacity as well as a small discharge lag and is capable of cutting off a follow current.