Patents by Inventor Akio Yanagida

Akio Yanagida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for purification of proanthocyanidin oligomer
    Patent number: 6800433
    Abstract: The present invention relates to a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises extracting the proanthocyanidin oligomers from raw materials containing the proanthocyanidin oligomers or crude purification products therefrom by solid-liquid extraction using methyl acetate as a liquid phase; a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises pretreating with an enzyme for hydrolysis raw materials containing the proanthocyanidin oligomers, crude purification products therefrom, or a solution containing one of these; and a process for purifying dimeric to pentameric proanthocyanidin oligomers with a uniform polymerization degree which comprises separating and purifying the proanthocyanidin oligomers by polymerization degree from raw materials containing the proanthocyanidin oligomers or crude purification products there from by normal phase silica gel liquid chromatography using as a mobile phase a single solvent or a mixed solvent of
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: October 5, 2004
    Assignees: Kyowa Hakko Kogyo Co., Ltd., The Nikka Whisky Distilling Co., Ltd.
    Inventors: Shinkichi Honda, Tomoya Takahashi, Ayako Kamimura, Takako Matsuoka, Tomomasa Kanda, Akio Yanagida, Kazuo Hieda
  • Process for the production of fruit polyphenols from unripe rosaceae fruit
    Patent number: 5994413
    Abstract: The present invention provides a fruit polyphenol obtained by subjecting unripe fruits of Rosaceae to pressing and/or extraction and then purifying the resulting juice or extract. The present invention further provides an antioxidant, a hypotensive agent, an antimutagenic agent, an antiallergic agent and an anticariogenic agent each comprising, as an effective component, a fruit polyphenol obtained by subjecting unripe fruits of Rosaceae to pressing and/or extraction and then purifying the resulting juice or extract. The fruit polyphenol of the present invention has various physiological activities, for example, an antioxidative activity, an ACE-inhibiting activity, an antimutagenic activity, a hyalulonidase-inhibiting activity and a GTase-inhibiting activity.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 30, 1999
    Assignee: The Nikka Whisky Distilling Co., Ltd.
    Inventors: Masayuki Tanabe, Tomomasa Kanda, Akio Yanagida
  • Process for the production of fruit polyphenols from unripe rosaceae fruit
    Patent number: 5932623
    Abstract: The present invention provides a fruit polyphenol obtained by subjecting unripe fruits of Rosaceae to pressing and/or extraction and then purifying the resulting juice or extract. The present invention further provides an antioxidant, a hypotensive agent, an antimutagenic agent, an antiallergic agent and an anticariogenic agent each comprising, as an effective component, a fruit polyphenol obtained by subjecting unripe fruits of Rosaceae to pressing and/or extraction and then purifying the resulting juice or extract. The fruit polyphenol of the present invention has various physiological activities, for example, an antioxidative activity, an ACE-inhibiting activity, an antimutagenic activity, a hyalulonidase-inhibiting activity and a GTase-inhibiting activity.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: August 3, 1999
    Assignee: The Nikka Whisky Distilling Co., Ltd.,
    Inventors: Masayuki Tanabe, Tomomasa Kanda, Akio Yanagida
  • Polyphenolic cosmetic composition
    Patent number: 5853728
    Abstract: Cosmetics are herein disclosed which contain a polyphenol derived from the fruits of Rosaceae, and the polyphenol is obtainable by purifying a pressed juice or an extract of the unripe fruits of the Rosaceae, for example, apples, pears or peaches. The cosmetics have many useful functions such as an ultraviolet light absorbing activity and a free radical erasing activity.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: December 29, 1998
    Assignee: The Nikka Whisky Distilling Co., Ltd.
    Inventors: Masayuki Tanabe, Tomomasa Kanda, Akio Yanagida, Toshihiko Shoji