Patents by Inventor Akira Kuninaka

Akira Kuninaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitumor compositions for non-injection administration
    Patent number: 4542021
    Abstract: An antitumor composition comprising a pharmacologically effective quantity of an ester of 1-.beta.-D-arabinofuranosylcytosine-5'-phosphate represented by the general formula ##STR1## where R is a monovalent aliphatic hydrocarbon group having 14 to 23 carbon atoms, and A designates a hydrogen atom or a pharmaceutically-acceptable alkali cation, and a vehicle is effective when administered by a non-injection method, particularly orally.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: September 17, 1985
    Assignees: Yamasa Shoyu Kabushiki Kaisha, Mineo Saneyoshi
    Inventors: Kenjiro Kodama, Akira Kuninaka, Mineo Saneyoshi
  • L-Lysine .alpha.-oxidase
    Patent number: 4234691
    Abstract: An L-lysine .alpha.-oxidase, that is, a novel L-amino acid oxidase having very high substrate-specificity to L-lysine is produced by culturing a specific microorganism belonging to Trichoderma in a medium.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: November 18, 1980
    Assignee: Yamasa Shoyu Kabushiki Kaisha
    Inventors: Hitoshi Kusakabe, Kenjiro Kodama, Yuichiro Midorikawa, Akira Kuninaka, Haruo Misono, Kenji Soda
  • Assay of L-lysine
    Patent number: 4224407
    Abstract: L-lysine contained in a sample can be efficiently determined by using the L-lysine .alpha.-oxidase. The preferred enzyme is an L-lysine .alpha.-oxidase, that is, a novel L-amino acid oxidase having very high substrate-specificity to L-lysine is produced by culturing a specific microorganism belonging to Trichoderma in a medium.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: September 23, 1980
    Assignee: Yamasa Shoyu Kabushiki Kaisha
    Inventors: Hitoshi Kusakabe, Akira Kuninaka, Kenji Soda
  • Assay kit for cAMP and/or cGMP and method of using the same
    Patent number: 4115538
    Abstract: An assay kit for assaying adenosine-3',5'-cyclic monophosphate, which is herein referred to as cAMP, guanosine-3',5'-cyclic monophosphate, which is herein referred to as a cGMP, or both; and said assay kit comprising,A container of Reagent 1 comprising succinyl cAMP tyrosine methyl ester; succinyl cGMP tyrosine methyl ester; succinyl cAMP tyrosine methyl ester and succinyl cGMP tyrosine methyl ester in admixture or both succinyl cAMP tyrosine methyl ester and succinyl cGMP tyrosine methyl ester in separate containers, said esters labelled with radioactive iodine;A container of Reagent 2 comprising an anti-cAMP serum, an anti-cGMP serum, an anti-cAMP and anti-cGMP serum in admixture or both anti-cAMP serum and anti-cGMP serum in separate containers;A container of Reagent 3 comprising an imidazole buffer solution of 0.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: September 19, 1978
    Assignee: Yamasu Shoyu Kabushiki Kaisha
    Inventors: Tomokazu Satoh, Junichi Takezawa, Akira Kuninaka, Miyuki Honma, Michio Ui
  • Process for producing pterin deaminases having antitumor activity
    Patent number: 3930955
    Abstract: The enzyme pterin deaminase may be used as an antitumor agent, and can be produced from cultures of the fungal genera Aspergillus, Mucor, Rhizopus, and Penicillium.
    Type: Grant
    Filed: May 13, 1974
    Date of Patent: January 6, 1976
    Assignee: Yamasa Shoyu Kabushiki Kaisha
    Inventors: Hitoshi Kusakabe, Kenjiro Kodama, Yuichirow Midorikawa, Haruhiko Machida, Akira Kuninaka, Hiroshi Yoshino