Patents by Inventor Akira KURISAKI

Akira KURISAKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200061007
    Abstract: The present invention aims to provide a growth inhibitor for cancer stem cells resistant to existing anticancer drug therapies, which growth inhibitor acts on the cells through growth inhibition and apoptosis. The growth inhibitor for cancer stem cells contains a retinoid agonist, preferably tamibarotene, alone or in combination with a rexinoid agonist, preferably bexarotene, as an effective component(s). The growth inhibitor for cancer stem cells enhances the effects of various anticancer drugs when the growth inhibitor is used in combination with the anticancer drugs.
    Type: Application
    Filed: November 4, 2019
    Publication date: February 27, 2020
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TMRC Co., Ltd.
    Inventors: Akira KURISAKI, Ying Ying WANG, Hitomi TAKADA, Hisao EKIMOTO
  • Publication number: 20170079942
    Abstract: The present invention aims to provide a growth inhibitor for cancer stem cells resistant to existing anticancer drug therapies, which growth inhibitor acts on the cells through growth inhibition and apoptosis. The growth inhibitor for cancer stem cells contains a retinoid agonist, preferably tamibarotene, alone or in combination with a rexinoid agonist, preferably bexarotene, as an effective component(s). The growth inhibitor for cancer stem cells enhances the effects of various anticancer drugs when the growth inhibitor is used in combination with the anticancer drugs.
    Type: Application
    Filed: May 20, 2015
    Publication date: March 23, 2017
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TMRC Co., Ltd.
    Inventors: Akira KURISAKI, Ying Ying WANG, Hitomi TAKADA, Hisao EKIMOTO
  • Publication number: 20160369349
    Abstract: [Problem to be Solved] To provide a new lung-cancer biomarker, which has a high detection efficiency and determines the type (histological type) of lung cancer. [Solution] LIPH (lipase, member H), which is enhanced in a plurality of lung cancer-derived cell lines compared to that in normal lung-derived epithelial cells and is almost surely expressed highly in lung cancer.
    Type: Application
    Filed: March 18, 2014
    Publication date: December 22, 2016
    Inventors: Yasuhiro SEKI, Norio SHIBATA, Makoto ASASHIMA, Akira KURISAKI