Patent number: 6664251
Abstract: Disclosed are benzothiazine derivatives represented by the following formula (I):
wherein the dashed line indicates the presence or absence of a bond; Z represents one of the following groups:
in which R1 and R2 individually represent alkyl, aralkyl or the like, R3 represents H, alkyl or the like, R4 represents H, aralkyl or the like, X1, X2 and X3 individually represent O or S, and G represents substituted or unsubstituted ethylene, trimethylene or the like; Q1 and Q2 individually represent H, OH, halogen, alkoxy or the like; A represents alkylene, alkenylene or the like; Y represents CH, C═ or N; when Y is CH, m stands for 0 or 1, n stands for 1 or 2, B represents O, S, carbonyl or the like, when Y is C═, m stands for 1, n stands for 1 or 2, B represents:
in which the double bond is linked to Y, R6 represents substituted or unsubstituted aryl or the like; when Y is N, m stands for 0 or 1, n stands for 2 or 3 and B represents carbonyl, sulfonyl
Type:
Grant
Filed:
September 19, 2001
Date of Patent:
December 16, 2003
Assignee:
Daiichi Suntory Pharma Co., Ltd.
Inventors:
Akira Mizuno, Makoto Shibata, Tomoe Iwamori, Norio Inomata