Abstract: Residual extracellular protease activities of a Bacillus subtilis strain can be further reduced by introducing a gene for the stimulation of extracellular protease levels into the genomic DNA of the strain.The resultant strain whose extracellular protease activities are further reduced is transformed with a recombinant plasmid for secretion of a desired protein and the desired protein can be efficiently produced and accumulated in the culture medium in a large amount. The accumulated desired protein can be easily recovered from the culture medium.For example, the accumulation level of human growth hormone secreted by a B. subtilis MT-430 strain carrying recombinant DNA phGH427 for the expression and secretion of human growth hormone can be increased five to tenfold as a result of the above treatment for reduction of the residual extracellular protease activities of the extracellular protease-activity-deficient strain.

Abstract: A expression-secretion vector is constructed by using a DNA sequence comprising a DNA fragment obtained by subjecting a DNA sequence consisting of a region involved in the expression of a gene coding for an extracellular enzyme of a bacterium of the genus Bacillus and a region involved in the secretion of the enzyme thus expressed to a deletion in the region involved in the secretion which can enhance the extracellular production of a protein dependent on the DNA fragment. By transforming a host bacterium with a recombinant DNA molecule formed by inserting a DNA fragment comprising a gene coding for a desired protein into the expression-secretion vector and then culturing the transformed host, the extracellular production of the desired protein in a large amount can be accomplished.

Abstract: A magnetic coating comprising magnetic powder, a binder and an organic solvent, characterized in that at least one component of the binder is a vinyl chloride copolymer having hydroxyl group, and carboxylic acid groups or sulfur- or phosphorus-containing strong acid radicals, and the comonomer supplying the hydroxyl groups is a monoallyl ether of polyhydroxy compound, and a magnetic recording medium made by coating a substrate with the magnetic coating.

Abstract: A cathode-ray tube in which outer convergence plates as constituents of the convergence plate assembly in the electron gun are supplied with individual voltages so that the horizontal misconvergence at the center portion and at the peripheral portions of the screen are positively corrected and in the arrangement the anode button is provided with a plurality of voltage supply pins. Further, the end portions of the two lead wires which are introduced form the anode button are opened outwardly so that the lead wires are prevented from coming in contact with the bead glass.

Abstract: An annular milling cutter for machining bevel gears is disclosed, which has a set of cutter blades including an inner blade and an outer one. A blade point width and a radius of curvature of a corner of a head of the outer blade are larger than the counterparts of the inner blade.

Abstract: A magnetic paint for magnetic recording media, comprising a magnetic powder and as a binder therefor, a copolymer resin containing 0.5 to 10% by weight of epoxy groups and 0.1 to 4.0% by weight of sulfur- or phosphorus-containing strong acid groups and having a vinyl chloride unit content of at least 60% by weight.

Abstract: This invention relates to DNA consisting of a DNA base sequence coding for the signal amino acid sequence:______________________________________ Met Phe Ala Lys Arg Phe Lys Thr Ser Leu Leu Pro Leu Phe Ala Gly Phe Leu Leu Leu Phe Tyr Leu Val Leu Ala Gly Pro Ala Ala Ala Ser Ala Glu Thr Ala Asn Lys Ser Asn Glu, ______________________________________and to DNA containing such a DNA base sequence. The DNA base sequence coding for said amino acid sequence includes, for example, ______________________________________ ATG TTT GCA AAA CGA TTC AAA ACC TCT TTA CTG CCG TTA TTC GCT GGA TTT TTA TTG CTG TTT TAT TTG GTT CTG GCA GGA CCG GCG GCT GCG AGT GCT GAA ACG GCG AAC AAA TCG AAT GAG. ______________________________________The desired products in cells can be secreted out of cells by the use of a vector containing DNA consisting of the DNA base sequence coding for said signal amino acid sequence.

Abstract: A magnetic paint for use in magnetic recording media comprising a magnetic powder and as a binder therefor, a copolymer resin having a bonded carboxyl group content of 0.3 to 5.0% by weight, a bonded epoxy group content of at least 0.5% by weight, and a vinyl chloride unit content of at least 60% by weight.

Abstract: A compound having the general formula ##STR1## wherein R.sub.1 is alkyl having 1-3 carbon atoms;R.sub.2 is alkyl having 1-3 carbon atoms, allyl, propargyl or haloalkenyl; andA is selected from the group consisting of ##STR2## wherein R.sub.3 is --SO.sub.2 R.sub.6 group, ##STR3## R.sub.4 is hydrogen, alkyl having 1-6 carbon atoms; phenyl or halophenyl; R.sub.5 is alkyl having 1-3 carbon atoms; X is oxygen or sulfur; and n is 0 or 1; wherein R.sub.6 is alkyl having 1-6 carbon atoms, haloalkyl having 1-6 carbon atoms or propenyl; R.sub.7 is hydrogen or alkyl having 1-4 carbon atoms; R.sub.8 is hydrogen, alkyl having 1-6 carbon atoms; propenyl or methoxy; R.sub.9 is hydrogen, alkyl having 1-8 carbon atoms, haloalkyl having 1-3 carbon atoms, alkoxy having 1-6 carbon atoms, propenyl or phenyl substituted with methyl; and Y and Z are oxygen or sulfur; and a metal salt or a quaternary ammonium salt of a compound defined herein above.The compound is useful as a herbicide.

Abstract: A compound having the general formula ##STR1## wherein R.sub.1 is ethyl or allyl; andR.sub.2 is alkyl having 1-4 carbon atoms;and a metal salt of the compound defined herein above.The compound is useful as herbicides.

Abstract: A process for producing a vinyl chloride polymer which comprises polymerizing vinyl chloride monomer or a mixture of it with another monomer copolymerizable therewith in an aqueous medium or in bulk, characterized in that the inside of the polymerization reactor is coated beforehand with the product of reaction of an oily or waxy cyclopentadiene polymer and a phenolic compound with or without an aldehyde compound.

Abstract: An automatic telephone answering device employs a single magnetic tape and a single driving mechanism for driving the magnetic tape. Whenever an incoming call is received, a control circuit of the device sets the driving mechanism into a playback mode to play to the calling party an outgoing message recorded at the beginning of a track on the single magnetic tape. Then, if there have been no previously recorded incoming messages, the device records the calling party's incoming message on the same track after detecting the end of the recorded outgoing message. However, if any incoming messages have been recorded previously on the same track of the single magnetic tape, the tape is advanced at high speed to a point beyond the last of these previously recorded incoming messages. Then, the present incoming message is recorded. As soon as the incoming call is terminated and the recording of the incoming message is ended, the device is set into a rewind mode.

Abstract: In a process for producing L-tryptophan which comprises cultivating an L-tryptophan-producing mutant of Bacillus subtilis under aerobic conditions in a nutrient culture medium containing anthranilic acid, a carbon source, a nitrogen source and a mineral source, and recovering the resultant L-tryptophan from the culture broth, the improvement wherein the mutant is a strain resistant to 5-fluorotryptophan and 8-azaguanine; and a pure culture of a microorganism strain used in said process.

Abstract: A grid structure for a color cathode ray tube comprises a substantially rectangular, one-piece frame consisting of a pair of first opposed frame portions and a pair of second opposed frame portions orthogonally related to the first frame portions and being integral with the latter at ends thereof, and grid elements secured to the first frame portions and extending therebetween generally parallel to the second frame portions in a longitudinally stressed condition, the second frame portions having at least recesses therein for enhancing the resilient bending thereof under loads applied to the first frame portions in directions urging the latter toward each other.

Abstract: In a grid structure for a color picture tube of the type comprised of a pair of elongated frame elements disposed in substantially parallel, spaced apart relation at the top and bottom, respectively, of the grid structure, a pair of mechanically resilient brace members having mid-portions extending between the frame elements at the opposite sides of the grid structure and end portions affixed to the frame elements for maintaining the latter in their spaced apart relation, and a plurality of grid wires defining slits therebetween extending between the frame elements and being welded or otherwise affixed to the latter adjacent the opposite ends of the grid wires while the grid wires are longitudinally tensioned and the brace members are prestressed by forces acting on the frame elements in the directions to urge the frame elements toward each other; each brace member has a cross-sectional shape, such as, a rectangular shape, providing different section moduli in respect to correspondingly different axes passing

Abstract: A flat thermionic cathode is provided with a substrate having at least one main heating element thereon to produce at least one substantially localized area of heat and a sub-heating element to substantially define a heating area, the localized area being produced within the heating area. A cathode element including electron emissive material is disposed at the localized area. While the localized area tends to produce a temperature gradient directed from the localized area toward the perimeter of the substrate so as to create thermal stress in the substrate along the perimeter thereof, the sub-heating element reduces this temperature gradient and, consequently, the thermal stress.

Abstract: A thermionic cathode structure includes a ceramic base plate, a heater layer of tungsten coated on the ceramic base plate, a cathode lead layer of tungsten formed on a ceramic insulating layer covering the heater layer, a base metal layer coated on the cathode lead layer, and a cathode material coated on the base metal layer.

Abstract: An indicator display tube in which indicator electrode units, each consisting of anode and cathode segments, lie in the same plane and in which all of the cathode segments are simultaneously energized and the anode electrodes are energized on a time sequential basis in such a manner that only the indicator electrode unit having its anode electrodes energized will glow at a particular time. The cathode segments of each indicator unit are connected in parallel which substantially reduces the number of leads to the display tube over conventional indicators which require a separate lead for energizing each of the cathode segments. The indicator display tube has means for preventing accidental discharge of adjacent indicator electrode units which would produce erroneous message displays.

Abstract: A vital phenomenon recording and/or reproducing device such as an electrocardiograph, an electromyograph, an electroencephalograph, etc. comprises a main unit including at least a magnetic tape driving mechanism and a magnetic head, a recording attachment capable of being detachably connected to said main unit mechanically and electrically, and a reproducing attachment capable of being detachably connected to said main unit, to said recording attachment being connected a detector such as electrodes to be adhered to a body of a patient and to said reproducing attachment being connected a recorder, for example, an XY recorder.