Patents by Inventor Akira Nishizono

Akira Nishizono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11780841
    Abstract: The present disclosure provides a compound that is useful for the treatment and prophylaxis of rabies. The present disclosure provides a compound represented by formula XXIIF or formula XXIIB: wherein R1, R2A, R2B, R3, and R4 are defined in the specification, a solvent, or a pharmaceutically acceptable salt thereof, use of such a compound, solvate, or pharmaceutically acceptable salt thereof for the treatment or prophylaxis of rabies and cancer, a pharmaceutical composition comprising such a compound, solvate, or pharmaceutically acceptable salt thereof, and a method for the treatment or prophylaxis of rabies and cancer using the same.
    Type: Grant
    Filed: February 23, 2022
    Date of Patent: October 10, 2023
    Assignee: Irimajiri Therapeutics Inc.
    Inventors: Hiroyuki Kouji, Kentaro Yamada, Akira Katoh, Toshimasa Ishizaki, Shigeru Matsuoka, Akira Nishizono, Tadashi Mishina, Atsushi Yoshimori
  • Publication number: 20220331300
    Abstract: The present disclosure provides compounds useful in the treatment and prevention of rabies. The present disclosure provides compounds represented by formula XXIF or XXIB [in the formulas, R1, R2A, R2B, R3, and R4 are as defined in the specification], solvates or pharmaceutically acceptable salts thereof, the use of these compounds, solvates or pharmaceutically acceptable salts thereof to treat or prevent rabies, pharmaceutical compositions including these compounds, solvates or pharmaceutically acceptable salts thereof, and a method for treating and preventing rabies using the same.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 20, 2022
    Inventors: Shigeru MATSUOKA, Akira KATOH, Tadashi MISHINA, Kentaro YAMADA, Atsushi YOSHIMORI, Toshimasa ISHIZAKI, Akira NISHIZONO, Hiroyuki KOUJI
  • Publication number: 20220194942
    Abstract: The present disclosure provides a compound that is useful for the treatment and prophylaxis of rabies. The present disclosure provides a compound represented by formula XXIIF or formula XXIIB: wherein R1, R2A, R2B, R3, and R4 are defined in the specification, a solvent, or a pharmaceutically acceptable salt thereof, use of such a compound, solvate, or pharmaceutically acceptable salt thereof for the treatment or prophylaxis of rabies and cancer, a pharmaceutical composition comprising such a compound, solvate, or pharmaceutically acceptable salt thereof, and a method for the treatment or prophylaxis of rabies and cancer using the same.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 23, 2022
    Inventors: Hiroyuki Kouji, Kentaro Yamada, Akira Katoh, Toshimasa Ishizaki, Shigeru Matsuoka, Akira Nishizono, Tadashi Mishina, Atsushi Yoshimori
  • Patent number: 11292794
    Abstract: The present disclosure provides a compound that is useful for the treatment and prophylaxis of rabies. The present disclosure provides a compound represented by formula XXIF or formula XXIB: wherein R1, R2A, R2B, R3, and R4 are defined in the specification, a solvent, or a pharmaceutically acceptable salt thereof, use of such a compound, solvate, or pharmaceutically acceptable salt thereof for the treatment or prophylaxis of rabies and cancer, a pharmaceutical composition comprising such a compound, solvate, or pharmaceutically acceptable salt thereof, and a method for the treatment or prophylaxis of rabies and cancer using the same.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: April 5, 2022
    Assignee: Oita University Institute of Advanced Medicine, Inc.
    Inventors: Hiroyuki Kouji, Kentaro Yamada, Akira Katoh, Toshimasa Ishizaki, Shigeru Matsuoka, Akira Nishizono, Tadashi Mishina, Atsushi Yoshimori
  • Publication number: 20210214356
    Abstract: The present disclosure provides a compound that is useful for the treatment and prophylaxis of rabies. The present disclosure provides a compound represented by formula XXIF or formula XXIB: wherein R1, R2A, R2B, R3, and R4 are defined in the specification, a solvent, or a pharmaceutically acceptable salt thereof, use of such a compound, solvate, or pharmaceutically acceptable salt thereof for the treatment or prophylaxis of rabies and cancer, a pharmaceutical composition comprising such a compound, solvate, or pharmaceutically acceptable salt thereof, and a method for the treatment or prophylaxis of rabies and cancer using the same.
    Type: Application
    Filed: February 14, 2020
    Publication date: July 15, 2021
    Inventors: Hiroyuki Kouji, Kentaro Yamada, Akira Kato, Toshimasa Ishizaki, Shigeru Matsuoka, Akira Nishizono, Tadashi Mishina, Atsushi Yoshimori
  • Patent number: 9365637
    Abstract: The present invention provides: a novel antiviral agent containing a human antibody ? light chain, a novel human abzyme containing a human antibody ? light chain; a polynucleotide, a vector, and a transformant, encoding a human antibody ? light chain of the above; a primer set for effectively obtaining a human antibody ? light chain having a function as an antiviral agent or abzyme; and a method for producing a polynucleotide and a method for producing a polypeptide, each of which method utilizes the primer set.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: June 14, 2016
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Taizo Uda, Emi Hifumi, Akira Nishizono, Mitsue Arakawa
  • Publication number: 20120322135
    Abstract: The present invention provides: a novel antiviral agent containing a human antibody ? light chain, a novel human abzyme containing a human antibody ? light chain; a polynucleotide, a vector, and a transformant, each of which relating to the containing a human antibody ? light chain of the above; a primer set for effectively obtaining a human antibody ? light chain having a function as an antiviral agent or abzyme; and a method for producing a polynucleotide and a method for producing a polypeptide, each of which method utilizes the primer set.
    Type: Application
    Filed: February 21, 2011
    Publication date: December 20, 2012
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Taizo Uda, Emi Hifumi, Akira Nishizono, Mitsue Arakawa
  • Patent number: 7341988
    Abstract: To provide a novel preventive and/or therapeutic agent against a virus, disclosed is a preventive and/or therapeutic agent against a viral infection containing geranyl-geranyl acetone as an active ingredient. Also, disclosed are inducers for increasing the activity of an anitiviral factor and for protein kinase containing geranyl-geranyl acetone as an active ingredient. Moreover, a method for preventing and/or treating a viral infection which contains administering a patient a effective amount of an agent containing geranyl-geranyl acetone as an active ingredient.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: March 11, 2008
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Akira Nishizono, Masako Unoshima, Hideo Iwasaka, Takayuki Noguchi
  • Publication number: 20040265319
    Abstract: To provide a novel preventive and/or therapeutic agent against a virus, disclosed is a preventive and/or therapeutic agent against a viral infection containing geranyl-geranyl acetone as an active ingredient. Also, disclosed are inducers for increasing the activity of an anitiviral factor and for protein kinase containing geranyl-geranyl acetone as an active ingredient. Moreover, a method for preventing and/or treating a viral infection which contains administering a patient a effective amount of an agent containing geranyl-geranyl acetone as an active ingredient.
    Type: Application
    Filed: August 23, 2004
    Publication date: December 30, 2004
    Inventors: Akira Nishizono, Masako Unoshima, Hideo Iwasaka, Takayuki Noguchi