Patents by Inventor Akira Sakaguchi

Akira Sakaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210054061
    Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.
    Type: Application
    Filed: April 15, 2019
    Publication date: February 25, 2021
    Applicants: National University Corporation Okayama University, NIIGATA UNIVERSITY, National University Corporation Gunma University, Kawasaki Gakuen Educational Foundation
    Inventors: Masakiyo SAKAGUCHI, Shinichi TOYOOKA, Shuta TOMIDA, Kazuhiko SHIEN, Hiroki SATO, Rie KINOSHITA, Junichiro FUTAMI, Kota ARAKI, Mikio OKAZAKI, Eisaku KONDO, Yusuke INOUE, Akira YAMAUCHI
  • Publication number: 20210023868
    Abstract: Disclosed is a printed object which, even if using a receptive layer that is difficult for a monomer in an active energy ray curable ink to penetrate, has excellent adhesion between the active energy ray curable ink and the receptive layer, and in which the amount of unreacted monomer dissipated from the printed object is low. This printed object includes an ink receptive layer laminated on a substrate surface and having an ink absorption rate of 100% or less, and an ink layer laminated on a surface of the ink receptive layer and made from an active energy ray curable ink which includes a polymerizable compound, wherein the glass transition temperature of the polymerizable compound is ?45-25° C.
    Type: Application
    Filed: March 27, 2019
    Publication date: January 28, 2021
    Inventors: Yasuhiro ANZAI, Naoyuki MASUDA, Akira SUETSUGU, Shinya SAKAGUCHI, Mami SAITO
  • Patent number: 10816461
    Abstract: A gas sensor includes: a gas detection unit including a light source and a detector; and a gas passage including a first end, a second end and a hollow part. The hollow part has a shape in which a cross-sectional area of a flow passage grows smaller. The gas passage includes: a member that divides the hollow part into at least a first area and a second area; a gas inflow port; and a gas outflow port. The gas flows from the gas inflow port into the hollow part, flows in the first area to arrive at the gas detection unit, and the gas located in the gas detection unit flows in the second area and flows out from the gas outflow port.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: October 27, 2020
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Kiminori Mizuuchi, Masaki Yamamoto, Akira Sakaguchi, Hidenori Watanabe, Tomoyoshi Tokumaru, Tsugumasa Hitomi
  • Publication number: 20200189305
    Abstract: Provided are an on-machine development-type lithographic printing plate precursor including: an image-recording layer on an aluminum support having an anode oxide film, in which an end portion of the lithographic printing plate precursor has a shear droop shape, the image-recording layer contains a compound having a support adsorptive property, having a molecular weight of 1,000 or less, and not having an unsaturated double bond group in a molecule, and a content of the compound is substantially the same in a plane of the image-recording layer and a method for producing a lithographic printing plate in which the lithographic printing plate precursor is used.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Applicant: FUJIFILM Corporation
    Inventors: Akira SAKAGUCHI, Yuki SAKAMOTO, Mitsuhiro FUJITA, Yusuke NAMBA
  • Patent number: 10600552
    Abstract: The invention is directed to a surface mountable reactor including: a coil 60; a first magnetic core 5 including an axial portion 5a around which the coil 60 is disposed and flange portions 5b and 5c at both ends thereof; a second magnetic core 10 disposed outside the coil 60 to connect the flange portions of the first magnetic core 5; and a resin mount 30 disposed outside the coil 60, wherein the second magnetic core 10 includes a plurality of components 10a and 10b separable toward outside the coil 60, the circumference of the coil 60 is surrounded by the second magnetic core 10 and the resin mount 30, and the coil 60 has end portions 65 disposed outside the resin mount 30, and to a method for fabrication thereof.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: March 24, 2020
    Assignee: HITACHI METALS, LTD.
    Inventors: Mutsuhito Sakaguchi, Akira Itoh, Ryouji Zenitani
  • Patent number: 10346073
    Abstract: A storage control apparatus includes a memory and a processor. The memory stores selection condition information relating to a selection condition for storage devices to construct a RAID, group information relating to groups to which the storage devices belong, and connection information indicating a connection configuration of the storage devices. The processor is configured to perform a procedure including: selecting the storage devices that match the selection condition information; extracting groups to which the selected storage devices belong based on the group information; assigning group priorities, which indicate selection priorities in units of the groups of the storage devices, to the extracted groups based on the connection information; and selecting one storage device from each of the extracted groups in accordance with the group priorities until a predetermined number of storage devices have been selected.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: July 9, 2019
    Assignee: FUJITSU LIMITED
    Inventors: Atsuhiro Otaka, Akiko Sakaguchi, Hidetoshi Satou, Takahiro Yumoto, Akira Yamazaki
  • Publication number: 20190073396
    Abstract: A method, system and computer program product for storing a sub-table by deciding one of a plurality of table storage areas, the sub-tables resulting from partitioning of a table in a database. To provide efficient table partitioning, a database is described for distributively locating a plurality of sub-tables resulting from partitioning of a table in a database. This includes an acquiring section that monitors access occurrences to each of the sub-tables to acquire a history of access occurrences. Also a deciding section decides a table storage area in which a sub-table is to be located, based on the history of access occurrences to each of the sub-tables.
    Type: Application
    Filed: November 7, 2018
    Publication date: March 7, 2019
    Inventors: Soh Kaijima, Masahiro Ohkawa, Akira Sakaguchi, Masakazu Sano
  • Publication number: 20190049370
    Abstract: A gas sensor includes: a gas detection unit including a light source and a detector; and a gas passage including a first end, a second end and a hollow part. The hollow part has a shape in which a cross-sectional area of a flow passage grows smaller. The gas passage includes: a member that divides the hollow part into at least a first area and a second area; a gas inflow port; and a gas outflow port. The gas flows from the gas inflow port into the hollow part, flows in the first area to arrive at the gas detection unit, and the gas located in the gas detection unit flows in the second area and flows out from the gas outflow port.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventors: Kiminori MIZUUCHI, Masaki YAMAMOTO, Akira SAKAGUCHI, Hidenori WATANABE, Tomoyoshi TOKUMARU, Tsugumasa HITOMI
  • Patent number: 10169420
    Abstract: A method, system and computer program product for storing a sub-table by deciding one of a plurality of table storage areas, the sub-tables resulting from partitioning of a table in a database. To provide efficient table partitioning, a database is described for distributively locating a plurality of sub-tables resulting from partitioning of a table in a database. This includes an acquiring section that monitors access occurrences to each of the sub-tables to acquire a history of access occurrences. Also a deciding section decides a table storage area in which a sub-table is to be located, based on the history of access occurrences to each of the sub-tables.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: January 1, 2019
    Assignee: International Business Machines Corporation
    Inventors: Soh Kaijima, Masahiro Ohkawa, Akira Sakaguchi, Masakazu Sano
  • Publication number: 20180052889
    Abstract: A method, system and computer program product for storing a sub-table by deciding one of a plurality of table storage areas, the sub-tables resulting from partitioning of a table in a database. To provide efficient table partitioning, a database is described for distributively locating a plurality of sub-tables resulting from partitioning of a table in a database. This includes an acquiring section that monitors access occurrences to each of the sub-tables to acquire a history of access occurrences. Also a deciding section decides a table storage area in which a sub-table is to be located, based on the history of access occurrences to each of the sub-tables.
    Type: Application
    Filed: October 27, 2017
    Publication date: February 22, 2018
    Inventors: Soh Kaijima, Masahiro Ohkawa, Akira Sakaguchi, Masakazu Sano
  • Patent number: 9864777
    Abstract: To provide efficient table partitioning, a database is described for distributively locating a plurality of sub-tables resulting from partitioning of a table in a database. This includes an acquiring section that monitors access occurrences to each of the sub-tables to acquire a history of access occurrences. Also a deciding section decides a table storage area in which a sub-table is to be located, based on the history of access occurrences to each of the sub-tables.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: January 9, 2018
    Assignee: International Business Machines Corporation
    Inventors: Soh Kaijima, Masahiro Okawa, Akira Sakaguchi, Masakazu Sano
  • Publication number: 20150355450
    Abstract: The present application provides an optical observation device having a first optical axis and a second optical axis different in direction from the first optical axis, the observation device including a splitter configured to split image light into first light along the first optical axis and second light along the second optical axis, the image light representing an image of an observation target; and a magnifier configured to change optical magnification for at least one of a first image represented by the first light and a second image represented by the second light. The splitter includes a first area, which receives the image light, and a second area, which receives the image light next to the first area. The first and second areas allow partial passage of the image light to generate the first light. The first area partially reflects the image light to generate the second light.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 10, 2015
    Applicant: PANASONIC HEALTHCARE HOLDINGS CO., LTD.
    Inventor: Akira SAKAGUCHI
  • Patent number: 9091855
    Abstract: An observation apparatus comprising: a beam-splitter including first and second plane-parallel plates respectively having first and second faces and third and fourth faces parallel to one another, and a light-splitting section allowing T % of incident light from a first-and-third-face side to pass therethrough to a second-and-fourth-face side, as transmitted light, while reflecting (100?T) % thereof in a direction parallel with the first to fourth faces as reflected light; and first and second observation optical systems to observe an entire observation target and partially magnify and observe the target, respectively, the first and second plane-parallel plates including light-reducing sections, allowing T % of the incident light to pass therethrough, in areas through which neither the incident nor transmitted light pass, the beam splitter arranged so that the first and third faces oppose the target and the transmitted and reflected lights are guided to the first and second observation optical systems, respec
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: July 28, 2015
    Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.
    Inventor: Akira Sakaguchi
  • Patent number: 8949192
    Abstract: A method of controlling access to a database includes autonomously archiving data within a database from a first storage device into a second storage device, according to an archive condition; the archive condition being input in conjunction with the data and being associated with the data; accepting an input of an access command to the database; determining whether data to be accessed in response to the access command input has already been archived in the second storage device based on the access command and the archive condition; and accessing data included in the database or data archived in the second storage device according to the access command based on the determination.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: February 3, 2015
    Assignee: International Business Machines Corporation
    Inventors: Soh Kaijima, Masahiro Ohkawa, Akira Sakaguchi
  • Patent number: 8940933
    Abstract: The present invention provides a method for producing polyoxyalkylene alkyl ether carboxylic acid and a salt thereof, including supplying polyoxyalkylene alkyl ether, oxygen, and water to a continuous stirred tank reactor containing a noble metal catalyst to oxidize the polyoxyalkylene alkyl ether with oxygen, in which the molar ratio of the salt of polyoxyalkylene alkyl ether carboxylic acid to the polyoxyalkylene alkyl ether in the continuous stirred tank reactor is controlled to 0.33 to 49.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: January 27, 2015
    Assignee: Kao Corporation
    Inventors: Takeshi Shirasawa, Yasuo Amishige, Kaoru Omae, Akira Matsunaga, Akira Sakaguchi
  • Patent number: 8915672
    Abstract: The present invention provides a movable breakwater that can do with a small amount of compressed air supplied to raise the buoyant steel pipe. The buoyant steel pipe 6 includes a buoyancy tank 6d in which gas is filled, an air chamber 6e provided above the buoyancy tank 6d, a penetration pipe 19 that penetrates through the buoyancy tank 6d and feeds compressed air supplied from a pressure accumulator tank 13 to the air chamber 6e, and an open chamber 6f, whose top side is open, provided above the air chamber 6e and in the buoyant steel pipe 6 at the upper end portion thereof.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: December 23, 2014
    Assignee: Mitsubishi Heavy Industries Bridge & Steel Structures Engineering Co., Ltd.
    Inventors: Hirofumi Inagaki, Yasuhiro Iida, Keiji Kanai, Makoto Kobayashi, Akira Sakaguchi, Taro Arikawa, Hirohide Kimura, Hisanobu Nagatomo, Kazuyoshi Kihara
  • Patent number: 8901348
    Abstract: The invention relates to a method for manufacturing a polyoxyethylene alkyl ether acetic acid, including feeding oxygen into a liquid phase containing polyoxyethylene ether having a hydrocarbon group at the end (hereinafter, it may also be referred to as a polyoxyethylene alkyl ether) and water, and dehydrogenating and oxidizing the polyoxyethylene alkyl ether in the presence of a platinum catalyst, in which the mass ratio between the total mass of the polyoxyethylene alkyl ether and the polyoxyethylene alkyl ether acetic acid and the mass of water in the liquid phase ((polyoxyethylene alkyl ether+polyoxyethylene alkyl ether acetic acid)/water) is 60/40 to 95/5.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: December 2, 2014
    Assignee: Kao Corporation
    Inventor: Akira Sakaguchi
  • Publication number: 20140088323
    Abstract: The invention relates to a method for manufacturing a polyoxyethylene alkyl ether acetic acid, including feeding oxygen into a liquid phase containing polyoxyethylene ether having a hydrocarbon group at the end (hereinafter, it may also be referred to as a polyoxyethylene alkyl ether) and water, and dehydrogenating and oxidizing the polyoxyethylene alkyl ether in the presence of a platinum catalyst, in which the mass ratio between the total mass of the polyoxyethylene alkyl ether and the polyoxyethylene alkyl ether acetic acid and the mass of water in the liquid phase ((polyoxyethylene alkyl ether+polyoxyethylene alkyl ether acetic acid)/water) is 60/40 to 95/5.
    Type: Application
    Filed: June 7, 2012
    Publication date: March 27, 2014
    Applicant: KAO CORPORATION
    Inventor: Akira Sakaguchi
  • Patent number: 8585583
    Abstract: A working unit of a manipulator includes a hollow joint shaft, wires disposed as power transmitting members in the hollow joint shaft, and a distal-end working unit mounted on an end of the hollow joint shaft and movable by the wires. The wires are wound around respective tubular members in the distal-end working unit. The hollow joint shaft has a pair of visual checking holes defined in respective side walls thereof near the distal end thereof for allowing the wires to be visually checked therethrough. The visual checking holes are positioned to expose the tubular members therethrough.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: November 19, 2013
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Akira Sakaguchi, Hiroaki Sano
  • Publication number: 20130229707
    Abstract: An observation apparatus comprising: a beam-splitter including first and second plane-parallel plates respectively having first and second faces and third and fourth faces parallel to one another, and a light-splitting section allowing T % of incident light from a first-and-third-face side to pass therethrough to a second-and-fourth-face side, as transmitted light, while reflecting (100?T) % thereof in a direction parallel with the first to fourth faces as reflected light; and first and second observation optical systems to observe an entire observation target and partially magnify and observe the target, respectively, the first and second plane-parallel plates including light-reducing sections, allowing T % of the incident light to pass therethrough, in areas through which neither the incident nor transmitted light pass, the beam splitter arranged so that the first and third faces oppose the target and the transmitted and reflected lights are guided to the first and second observation optical systems, respec
    Type: Application
    Filed: April 15, 2013
    Publication date: September 5, 2013
    Applicant: Sanyo Electric Co., Ltd
    Inventor: Akira SAKAGUCHI