Patents by Inventor Akira Sezaki
Akira Sezaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240102918Abstract: An accuracy management method for executing accuracy management by using an accuracy management substance in a measurement device that measures a biological specimen includes: reading management information regarding the accuracy management substance from an information recording medium; selecting a treatment adapted to the read management information; executing the selected treatment; and updating the management information in the information recording medium according to the executed treatment.Type: ApplicationFiled: September 14, 2023Publication date: March 28, 2024Applicant: ARKRAY, Inc.Inventors: Akira SEZAKI, Hajime FUKUMARU, Takafumi AONO
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Patent number: 10527594Abstract: A liquid chromatography measurement method includes: switching between a first measurement mode using a liquid chromatography method in which hemoglobin A1c and a hemoglobin variant are measured in a measurement sample by sequentially delivering a first component-separating eluent, a second component-separating eluent and a wash eluent to an analytical column, and a second measurement mode using the liquid chromatography method in which the hemoglobin A1c is measured by sequentially delivering the first component-separating eluent and the wash eluent to the analytical column; delivering the wash eluent in the first measurement mode prior to an influence from the second component-separating eluent disappearing such that a first retention time of the hemoglobin A1c in the first measurement mode and a second retention time of the hemoglobin A1c in the second measurement mode are substantially the same as each other; and delivering the first component-separating eluent after the wash eluent.Type: GrantFiled: April 18, 2017Date of Patent: January 7, 2020Assignee: ARKRAY, Inc.Inventors: Akira Sezaki, Takeshi Takagi
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Publication number: 20180372698Abstract: A liquid chromatography device includes a column that separates components in a specimen sample, an eluent supply mechanism that alternately supplies two or more types of eluent to the column, and a detection apparatus into which the eluents are introduced after having passed through the column. The detection apparatus detects a specified component of the sample contained in the eluents. The detection apparatus includes a flow cell, a light source, a light-receiving unit, and a scattering plate. The flow cell includes a flow channel through which the eluents flow. The light source is provided outside of the flow cell and irradiates light onto the eluents flowing through the flow channel. The light-receiving unit is provided outside of the flow cell and receives light that has passed through the flow cell. The scattering plate is provided between the light source and the light-receiving unit along a direction of travel of light from the light source.Type: ApplicationFiled: June 20, 2018Publication date: December 27, 2018Applicant: ARKRAY, Inc.Inventors: Akira Sezaki, Takeshi Takagi
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Publication number: 20170307571Abstract: A liquid chromatography measurement method includes: switching between a first measurement mode using a liquid chromatography method in which hemoglobin A1c and a hemoglobin variant are measured in a measurement sample by sequentially delivering a first component-separating eluent, a second component-separating eluent and a wash eluent to an analytical column, and a second measurement mode using the liquid chromatography method in which the hemoglobin A1c is measured by sequentially delivering the first component-separating eluent and the wash eluent to the analytical column; delivering the wash eluent in the first measurement mode prior to an influence from the second component-separating eluent disappearing such that a first retention time of the hemoglobin A1c in the first measurement mode and a second retention time of the hemoglobin A1c in the second measurement mode are substantially the same as each other; and delivering the first component-separating eluent after the wash eluent.Type: ApplicationFiled: April 18, 2017Publication date: October 26, 2017Applicant: ARKRAY, Inc.Inventors: Akira SEZAKI, Takeshi TAKAGI
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Patent number: 9759696Abstract: A channel bubble reduction device includes a liquid accommodation portion, that accommodates a liquid, a liquid supply apparatus that, with a pushing operation of a rod, discharges the liquid through an aperture portion of a tube portion, a first channel that connects the aperture portion of the liquid supply apparatus with the liquid accommodation portion, and an air layer formation apparatus that forms an air layer in at least one of the first channel or the tube portion.Type: GrantFiled: May 29, 2013Date of Patent: September 12, 2017Assignee: ARKRAY, Inc.Inventors: Akira Sezaki, Tokuo Kasai
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Patent number: 9310342Abstract: A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.Type: GrantFiled: October 6, 2009Date of Patent: April 12, 2016Assignees: ARKRAY, Inc., Sekisui Medical Co., Ltd.Inventors: Toshikatsu Sakai, Akira Sezaki, Takeshi Takagi, Takuya Yotani, Makoto Takahara, Takayuki Oka
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Patent number: 9285347Abstract: A bubble reduction device, chromatography device, bubble reduction method and bubble reduction program capable of reducing bubbles in an eluent. Included are a liquid accommodation portion, a liquid supply apparatus, an air layer formation apparatus, a first channel and an evacuation portion. The liquid accommodation portion accommodates a liquid that is to elute an analysis component from a specimen adsorbed to an adsorption portion. The liquid supply apparatus, by operation of a rod pushing up and polling down, sucks and discharges the liquid through an aperture portion of a tube portion, the aperture portion being oriented upward. The air layer formation apparatus forms an air layer in the tube portion. The first channel connects the liquid supply apparatus with the liquid accommodation portion. The evacuation portion is connected to the first channel via a first switching valve and evacuates the air layer through the first channel.Type: GrantFiled: May 28, 2013Date of Patent: March 15, 2016Assignee: ARKRAY, Inc.Inventors: Seiji Satake, Tokuo Kasai, Akira Sezaki, Takeshi Matsubara
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Patent number: 8939018Abstract: An analyzing device includes a feeder connected to a container in which a sample is contained for sucking the sample from the container and feeding the sample, and a controller for performing control for feeding from the feeder to a measurer. In measuring the sample, the controller performs control so that results of a plurality of times of measurement are obtained with respect to the single container in which the sample is contained, without changing the container. This arrangement allows quick accuracy check.Type: GrantFiled: October 2, 2009Date of Patent: January 27, 2015Assignee: ARKRAY, Inc.Inventors: Toshikatsu Sakai, Akira Sezaki, Takeshi Takagi
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Publication number: 20130319087Abstract: A bubble reduction device, chromatography device, bubble reduction method and bubble reduction program capable of reducing bubbles in an eluent. Included are a liquid accommodation portion, a liquid supply apparatus, an air layer formation apparatus, a first channel and an evacuation portion. The liquid accommodation portion accommodates a liquid that is to elute an analysis component from a specimen adsorbed to an adsorption portion. The liquid supply apparatus, by operation of a rod pushing up and polling down, sucks and discharges the liquid through an aperture portion of a tube portion, the aperture portion being oriented upward. The air layer formation apparatus forms an air layer in the tube portion. The first channel connects the liquid supply apparatus with the liquid accommodation portion. The evacuation portion is connected to the first channel via a first switching valve and evacuates the air layer through the first channel.Type: ApplicationFiled: May 28, 2013Publication date: December 5, 2013Applicant: ARKRAY, Inc.Inventors: Seiji Satake, Tokuo Kasai, Akira Sezaki, Takeshi Matsubara
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Publication number: 20130319080Abstract: A channel bubble reduction device includes a liquid accommodation portion, that accommodates a liquid, a liquid supply apparatus that, with a pushing operation of a rod, discharges the liquid through an aperture portion of a tube portion, a first channel that connects the aperture portion of the liquid supply apparatus with the liquid accommodation portion, and an air layer formation apparatus that forms an air layer in at least one of the first channel or the tube portion.Type: ApplicationFiled: May 29, 2013Publication date: December 5, 2013Applicant: ARKRAY, Inc.Inventors: Akira Sezaki, Tokuo Kasai
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Patent number: 8495906Abstract: The present invention relates to a deaerator 2 including: a liquid flow space; reduced-pressure spaces 25A, 25B, and 25C; gas permeable films 21A, 21B, and 21C that separate these spaces; and a pump for discharging gas from within the reduced-pressure spaces 25A, 25B, and 25C to the outside, and to a liquid chromatograph equipped with the deaerator 2. The deaerator 2 further includes gas partial pressure variation suppression means 23A, 23B, 23C, 25Ab, 25Bb, 25Cb, 29A, 29B, and 29C for suppressing variations in partial pressures of a specific gas in the reduced-pressure spaces 25A, 25B, and 25C.Type: GrantFiled: February 8, 2007Date of Patent: July 30, 2013Assignee: Arkray, Inc.Inventors: Koji Sugiyama, Akira Sezaki, Takanori Kamada, Yoshikiyo Hongo
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Patent number: 8361390Abstract: The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator 4. The liquid chromatography apparatus X is further provided with a dissolved oxygen density adjusting means for maintaining a density of dissolved oxygen in an eluting solution to be supplied to a column 60 constant. Preferably, the dissolved oxygen density adjusting means is configured so as to adjust the density of the dissolved oxygen in the eluting solution by adjusting a degree of decompression in a decompression space of the deaerator 4 based on a measurement result by temperature measurement means 40A, 40B, and 40C for measuring the temperature of the eluting solution.Type: GrantFiled: February 8, 2007Date of Patent: January 29, 2013Assignee: Arkray, Inc.Inventors: Koji Sugiyama, Toshikatsu Sakai, Yoshikiyo Hongo, Akira Sezaki, Takanori Kamada
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Publication number: 20110186511Abstract: A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.Type: ApplicationFiled: October 6, 2009Publication date: August 4, 2011Applicants: ARKRAY, INC., SEKISUI MEDICAL CO., LTD.Inventors: Toshikatsu Sakai, Akira Sezaki, Takeshi Takagi, Takuya Yotani, Makoto Takahara, Takayuki Oka
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Publication number: 20110185797Abstract: An analyzing device includes a feeder connected to a container in which a sample is contained for sucking the sample from the container and feeding the sample, and a controller for performing control for feeding from the feeder to a measurer. In measuring the sample, the controller performs control so that results of a plurality of times of measurement are obtained with respect to the single container in which the sample is contained, without changing the container. This arrangement allows quick accuracy check.Type: ApplicationFiled: October 2, 2009Publication date: August 4, 2011Applicant: ARKRAY, INC.Inventors: Toshikatsu Sakai, Akira Sezaki, Takeshi Takagi
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Publication number: 20100288024Abstract: The present invention relates to a deaerator 2 including: a liquid flow space; reduced-pressure spaces 25A, 25B, and 25C; gas permeable films 21A, 21B, and 21C that separate these spaces; and a pump for discharging gas from within the reduced-pressure spaces 25A, 25B, and 25C to the outside, and to a liquid chromatograph equipped with the deaerator 2. The deaerator 2 further includes gas partial pressure variation suppression means 23A, 23B, 23C, 25Ab, 25Bb, 25Cb, 29A, 29B, and 29C for suppressing variations in partial pressures of a specific gas in the reduced-pressure spaces 25A, 25B, and 25C.Type: ApplicationFiled: February 8, 2007Publication date: November 18, 2010Applicant: ARKRAY, INC.Inventors: Koji Sugiyama, Akira Sezaki, Takanori Kamada, Yoshikiyo Hongo
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Publication number: 20090275119Abstract: The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator 4. The liquid chromatography apparatus X is further provided with a dissolved oxygen density adjusting means for maintaining a density of dissolved oxygen in an eluting solution to be supplied to a column 60 constant. Preferably, the dissolved oxygen density adjusting means is configured so as to adjust the density of the dissolved oxygen in the eluting solution by adjusting a degree of decompression in a decompression space of the deaerator 4 based on a measurement result by temperature measurement means 40A, 40B, and 40C for measuring the temperature of the eluting solution.Type: ApplicationFiled: February 8, 2007Publication date: November 5, 2009Applicant: ARKRAY, INC.Inventors: Koji Sugiyama, Toshikatsu Sakai, Yoshikiyo Hongo, Akira Sezaki, Takanori Kamada