Abstract: In order to provide tobacco resistant to a virus, tobacco in accordance with the present invention is arranged such that: (i) a translation initiation factor eIF(iso)4E protein which is non-functional with respect to a virus is produced or (ii) expression of a translation initiation factor eIF(iso)4E gene is suppressed; and (a) a translation initiation factor eIF4E2 protein, which is non-functional with respect to a virus, is produced or (b) expression of a translation initiation factor eIF4E2 gene is suppressed.

Abstract: A virus-resistant tobacco in accordance with the present invention is such that it includes a mutation in a translation initiation factor eIF(iso)4E gene, the mutation causing production of an eIF(iso)4E protein which is non-functional with respect to a virus or suppressing expression of the eIF(iso)4E gene, or a virus-resistant tobacco in accordance with the present invention is such that an expression level of the eIF(iso)4E gene is 20% or lower as compared to a wild type.

Abstract: In order to provide tobacco resistant to a virus, tobacco in accordance with the present invention is arranged such that: (i) a translation initiation factor eIF(iso)4E protein which is non-functional with respect to a virus is produced or (ii) expression of a translation initiation factor eIF(iso)4E gene is suppressed; and (a) a translation initiation factor eIF4E2 protein, which is non-functional with respect to a virus, is produced or (b) expression of a translation initiation factor eIF4E2 gene is suppressed.

Abstract: A virus-resistant tobacco in accordance with the present invention is such that it includes a mutation in a translation initiation factor eIF(iso)4E gene, the mutation causing production of an eIF(iso)4E protein which is non-functional with respect to a virus or suppressing expression of the eIF(iso)4E gene, or a virus-resistant tobacco in accordance with the present invention is such that an expression level of the eIF(iso)4E gene is 20% or lower as compared to a wild type.

Abstract: The present invention is an intramedullary nail (100) to be used by being intramedullarily inserted into a bone, having a nail body (110) comprising an axial hole (113) extending from an opening formed at a proximal end portion toward a distal end portion along an axis line and a transverse hole (114) intersecting with the axis line, and having: an engaging member (221) comprising an engaging portion (221b) at distal end thereof engageable with a bone fastener inserted through the transverse hole and arranged so as to be shiftable in the axial hole in a manner where the distal end portion is engageable and disengageable with the bone fastener (10); an adjusting member (222) controlling the position of the engaging member; and an elastic member (125) for charging, against the nail body, the engaging member in a direction opposite the controlling direction by the adjusting member.

Abstract: The present invention is an intramedullary nail (100) to be used by being intramedullarily inserted into a bone, having a nail body (110) comprising an axial hole (113) extending from an opening formed at a proximal end portion toward a distal end portion along an axis line and a transverse hole (114) intersecting with the axis line, and having: an engaging member (221) comprising an engaging portion (221b) at distal end thereof engageable with a bone fastener inserted through the transverse hole and arranged so as to be shiftable in the axial hole in a manner where the distal end portion is engageable and disengageable with the bone fastener (10); an adjusting member (222) controlling the position of the engaging member; and an elastic member (125) for charging, against the nail body, the engaging member in a direction opposite the controlling direction by the adjusting member.