Abstract: The present invention provides that exosomes from ovarian cancer patients contain nuclear proteins and genomic DNA at an increased proportion. As such, detecting nuclear-derived exosomes provides a method of early detection of ovarian cancer. Furthermore, the level of nuclear-derived exosomes can be monitored over time to assess responsiveness to genotoxic therapy.

Abstract: This invention provides a kit and device for detection of uterine leiomyosarcoma, and a method for detecting uterine leiomyosarcoma. This invention provides a kit and device for detection of uterine leiomyosarcoma containing a nucleic acid capable of specifically binding to a miRNA in a sample from a subject or a complementary strand thereof and a method for detecting uterine leiomyosarcoma including measuring the miRNA in vitro.

Abstract: [Problem] To provide: a marker and a kit both for use in the prediction of ovarian cancer prognosis; and a prognosis prediction method. [Solution] A marker and a kit, both for use in the prediction of ovarian cancer prognosis, each of said marker and kit containing a transcript of matrix metalloprotease (MMP) 1 gene; and a method for predicting ovarian cancer prognosis using the marker or the kit, in which the expression level of matrix metalloprotease (MMP) 1 gene in a biological sample collected from a subject is by detecting an ovarian cancer prognosis prediction marker comprising a transcript of matrix metalloprotease (MMP) 1 gene and then obtaining a detection value of the ovarian cancer prognosis prediction marker.

Abstract: An organic device has a hole current-electron current conversion layer which comprises a laminate of an electron transportation section and a hole transportation section. The electron transportation section includes a charge transfer complex formed upon an oxidation-reduction reaction between a reduced low work function metal and an electron-accepting organic compound, the reduced metal being produced upon an in-situ thermal reduction reaction caused upon contact, through lamination or mixing by co-deposition, of an organic metal complex compound or an inorganic compound containing at least one metal ion selected from ions of low work function metals having a work function of not more than 4.0 eV, and a thermally reducible metal capable of reducing a metal ion contained in the organic metal complex compound or the inorganic compound in vacuum to the corresponding metal state, and the electron transportation section having the electron-accepting organic compound in the state of radical anions.

Abstract: Susceptibility of a tumor cell to an anticancer agent is tested by measuring an expression level or levels of a gene or genes selected from the group consisting of the genes listed in Tables 3 and 4 in a tumor cell collected from a cancer patient treated with an anticancer agent (E7070 and related compounds thereof), or causing the anticancer agent to act on a tumor cell collected from a cancer patient and measuring an expression level or levels of a gene or genes selected from the group consisting of the genes listed in Tables 3 and 4 in the tumor cell, and determining that the tumor cell is susceptible to the anticancer agent when the expression level or levels of the gene or genes listed in Table 3 increase, or the expression level or levels of the gene or genes listed in Table 4 decrease.

Abstract: A portable radio receiver with an automatic power generator has a ring-shaped receiver body, a coil, a magnetic material, a rechargeable battery and a receiver unit. The coil is wound in proximity to the receiver body. The magnetic material is movably located inside the coil. The rechargeable battery is provided for accumulating electric charge which is generated on the coil as the magnetic material moves. The receiver unit utilizes the rechargeable battery as a power source.

Abstract: An organic device has a hole current-electron current conversion layer which comprises a laminate of an electron transportation section and a hole transportation section. The electron transportation section includes a charge transfer complex formed upon an oxidation-reduction reaction between a reduced low work function metal and an electron-accepting organic compound, the reduced metal being produced upon an in-situ thermal reduction reaction caused upon contact, through lamination or mixing by co-deposition, of an organic metal complex compound or an inorganic compound containing at least one metal ion selected from ions of low work function metals having a work function of not more than 4.0 eV, and a thermally reducible metal capable of reducing a metal ion contained in the organic metal complex compound or the inorganic compound in vacuum to the corresponding metal state, and the electron transportation section having the electron-accepting organic compound in the state of radical anions.

Abstract: Disclosed is a method for forming a thin-film layer, such as a metallic film or a transparent conductive film, on a functional organic layer formed from an organic compound, by means of a sputtering method performed at a low discharge voltage and a low gas pressure, without imparting any damage to the surface of the organic layer. The thin-film layer is formed by use of a facing-targets-type sputtering apparatus including a pair of facing targets disposed a predetermined distance away from each other; an electron reflection electrode disposed on the periphery of each target; and magnetic field generation means disposed at the sides of each target. The magnetic field generation means generates a magnetic field extending from one target to the other so as to surround a confinement space provided between the paired targets, as well as a magnetic field having a portion parallel to the surface of each target in the vicinity of a peripheral edge portion of the target.

Abstract: Susceptibility of a tumor cell to an anticancer agent is tested by measuring an expression level or levels of a gene or genes selected from the group consisting of the genes listed in Tables 3 and 4 in a tumor cell collected from a cancer patient treated with an anticancer agent (E7070 and related compounds thereof), or causing the anticancer agent to act on a tumor cell collected from a cancer patient and measuring an expression level or levels of a gene or genes selected from the group consisting of the genes listed in Tables 3 and 4 in the tumor cell, and determining that the tumor cell is susceptible to the anticancer agent when the expression level or levels of the gene or genes listed in Table 3 increase, or the expression level or levels of the gene or genes listed in Table 4 decrease.

Abstract: An organic electroluminescent device includes at least one luminescent layer, constituted from an organic compound, provided between a cathode electrode and an anode electrode opposed to the cathode electrode; and an organic compound layer doped with a metal capable of acting as an electron-donating dopant, the organic compound layer being disposed as a metal doping layer in an interfacial surface with the cathode electrode. An emission spectrum of light emitted from the organic electroluminescent device is controlled by varying a layer thickness of the metal doping layer. Alternatively, the organic compound layer can be doped with an electron-accepting compound, disposed as a chemical doping layer in an interfacial surface with the anode electrode on the luminescent layer side; wherein an emission spectrum of light emitted from the organic electroluminescent device is controlled by varying a layer thickness of the chemical doping layer.

Abstract: Disclosed is a method for forming a thin-film layer, such as a metallic film or a transparent conductive film, on a functional organic layer formed from an organic compound, by means of a sputtering method performed at a low discharge voltage and a low gas pressure, without imparting any damage to the surface of the organic layer. The thin-film layer is formed by use of a facing-targets-type sputtering apparatus including a pair of facing targets disposed a predetermined distance away from each other; an electron reflection electrode disposed on the periphery of each target; and magnetic field generation means disposed at the sides of each target. The magnetic field generation means generates a magnetic field extending from one target to the other so as to surround a confinement space provided between the paired targets, as well as a magnetic field having a portion parallel to the surface of each target in the vicinity of a peripheral edge portion of the target.

Abstract: A method for manufacturing an organic EL display panel includes; forming first display electrodes corresponding to emitting portions and bonding pads arranged at a periphery of an image-region as a patterning step; forming electrically insulative ramparts for exposing at least portions of the first display electrodes and protruding from the substrate as a rampart formation step, the each electrically insulative rampart having an overhanging portion projecting in a direction parallel to the substrate preferably at an upper and further having extensions each extending between the adjacent bonding pads to isolate the adjacent bonding pads each other and define a bonding-region between the adjacent extensions on each the bonding pad; depositing organic electroluminescent media onto exposed portions of the first display electrodes respectively, thereby forming organic function layers each including at least one organic electroluminescent medium on the first display electrodes; and forming second display electrodes

Abstract: A liquid crystal display unit uses a photoconductive type liquid crystal light valve. By using non-monochromatic light as the writing light, the light excitation can be induced near the surface layer of the photoconductive layer by light of a shorter wavelength and also on portions deep in the layer by light of a longer wavelength. Thus, it is possible to induce the light excitation effectively on the photoconductive layer even when it is thick.

Abstract: A colored precipitated calcium carbonate having a strong color fastness in water is produced by preparing an aqueous slurry containing calcium hydroxide and a water-soluble dye, for example, a direct dye, introducing a carbon dioxide-containing gas into the aqueous slurry, and collecting the resultant colored precipitated calcium carbonate from the aqueous slurry at a pH of 8.2 or more thereof.