Patents by Inventor Akira Yotsuji

Akira Yotsuji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5605921
    Abstract: The present invention relates to a compound represented by the general formula (1) or its salt, a process for producing the same, and an antifungal agent comprising the same as an effective component: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group bonded through a carbon atom in the ring to the main chain; R.sup.2 presents a hydrogen atom, a fluorine atom or a substituted or unsubstituted alkyl group; and R.sup.3 represents a cyano group, a thioamido group or a group represented by the formula ##STR2## in which R.sup.4 is a hydroxyl group or a group of the formula ##STR3## (R.sup.7 and R.sup.8, which may be the same or different, are hydrogen atoms or substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, amino, alkoxy, hydroxyl or heterocyclic groups, and may form a substituted or unsubstituted heterocyclic group together with the nitrogen atom to which R.sup.7 and R.sup.8 attach), R.sup.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: February 25, 1997
    Assignee: Toyama Chemical Co., Ltd.
    Inventors: Hiroyuki Imaizumi, Tetsuya Kajita, Kenichi Takashima, Minako Yotsuji, Keiko Takakura, Akira Yotsuji, Junichi Mitsuyama, Katsumi Shimizu, Hiroshi Sakai, Hirokazu Narita
  • Patent number: 5378832
    Abstract: The present invention provides a polymer comprising a polysaccharide having excellent water absorption properties, moisture absorption properties, moisture retention properties and thickening properties. Said polysaccharide has the following properties: (A) the principal constituents of the sugar composition are rhamnose, fucose, glucose and glucuronic acid which are present in a molar ratio of (1-4):2:(1-8):(1-4); (B) elemental analysis (wt %):C: 36 .+-.3H: 7 .+-.1O: 56 .+-.4,containing 9-13% of crystalline water(C) solubility:slightly soluble in water; soluble in alkalies; insoluble in methanol, ethanol and acetone;(D) UV absorption spectrum:no absorption detected at 280 nm characteristic of proteins (peptides) or at 260 nm characteristic of nucleic acids; and(E) IR absorption spectrum:an absorption pattern characteristic of polysaccharides is observed near 800-1200.sup.-iSaid polysaccharide is produced by a fermentation method using a natural medium or a synthetic medium of Alcaligenes microorganism.
    Type: Grant
    Filed: July 20, 1993
    Date of Patent: January 3, 1995
    Assignees: Agency of Industrial Science and Technology, Kyowa Hokkoh Kogyo Co., Ltd.
    Inventors: Ryuichiro Kurane, Yasuhiro Nohata, Michio Shiomi, Shuichi Ishino, Akira Yotsuji, Hideki Murata, Seiji Sugimoto
  • Patent number: 5366989
    Abstract: The present invention relates to a compound represented by the general formula (1) or its salt, a process for producing the same, and an antifungal agent comprising the same as an effective component: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group bonded through a carbon atom in the ring to the main chain; R.sup.2 presents a hydrogen atom, a fluorine atom or a substituted or unsubstituted alkyl group; and R.sup.3 represents a cyano group, a thioamido group or a group represented by the formula ##STR2## in which R.sup.4 is a hydroxyl group or a group of the formula ##STR3## (R.sup.7 and R.sup.8, which may be the same or different, are hydrogen atoms or substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, amino, alkoxy, hydroxyl or heterocyclic groups, and may form a substituted or unsubstituted heterocyclic group together with the nitrogen atom to which R.sup.7 and R.sup.8 attach), R.sup.
    Type: Grant
    Filed: December 8, 1992
    Date of Patent: November 22, 1994
    Assignee: Toyama Chemical Co., Ltd.
    Inventors: Hiroyuki Imaizumi, Tetsuya Kajita, Kenichi Takashima, Minako Yotsuji, Keiko Takakura, Akira Yotsuji, Junichi Mitsuyama, Katsumi Shimizu, Hiroshi Sakai, Hirokazu Narita
  • Patent number: 4444753
    Abstract: A composition comprising a component obtained by deproteinizing an extract from the poison pouch contents of bee has an immunostimulating activity, a carcinostatic activity, an effect of enhancing the antibacterial activity of an antibacterial substance and an effect of enhancing the carcinostatic activity of a carcinostatic substance. This invention is directed to a carcinostatic, immunostimulating and antibacterial agent comprising said composition.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: April 24, 1984
    Assignee: Toyama Chemical Company, Ltd.
    Inventors: Isamu Saikawa, Takashi Yasuda, Shohachi Murakami, Toyoo Maeda, Akira Yotsuji, Masahiro Takahata, Hisatsugu Tsuda, Hidetada Mikami, Hiroshi Sakai, Toshinori Ohashi
  • Patent number: 4370316
    Abstract: A method for treating a host mammal having a decreased immunity, comprising administering to said host mammal an immunostimulating effective amount of the deproteinized extract from the poison pouch contents of bee B-T, is disclosed.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: January 25, 1983
    Assignee: Toyama Chemical Company, Ltd.
    Inventors: Isamu Saikawa, Takashi Yasuda, Shohachi Murakami, Toyoo Maeda, Akira Yotsuji, Masahiro Takahata, Hisatsugu Tsuda, Hidetada Mikami, Hiroshi Sakai, Toshinori Ohashi