Patents by Inventor Akiyo Yamazaki

Akiyo Yamazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8299064
    Abstract: The present invention provides a fused polycyclic compound of the following formula, analogues thereof and pharmaceutically acceptable salts thereof; and agents for increasing the sugar-transporting capacity, hypoglycemic agents and pharmaceutical compositions containing the above compounds. This fused polycyclic compound has high medicinal properties and few side-effects, and a therapeutic effect on diabetes. wherein R represents an alkoxy group, R? represents an oxazolylpropionyl group or a thiazolylpropionyl group, and R? represent a hydrogen atom.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: October 30, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ryusuke Hirama, Seiji Niwa, Hideyuki Tanaka, Toshihiro Hatanaka, Yoko Masuzawa, Akiyo Yamazaki, Takao Ikenoue, Nobuo Kondo, Wataru Miyanaga, Masaru Takayanagi
  • Publication number: 20110160191
    Abstract: The present invention provides a fused polycyclic compound of the following formula, analogues thereof and pharmaceutically acceptable salts thereof; and agents for increasing the sugar-transporting capacity, hypoglycemic agents and pharmaceutical compositions containing the above compounds. This fused polycyclic compound has high medicinal properties and few side-effects, and a therapeutic effect on diabetes. wherein R represents an alkoxy group, R? represents an oxazolylpropionyl group or a thiazolylpropionyl group, and R? represent a hydrogen atom.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 30, 2011
    Applicant: Ajinomoto Co., Inc.
    Inventors: Ryusuke HIRAMA, Seiji Niwa, Hideyuki Tanaka, Toshihiro Hatanaka, Yoko Masuzawa, Akiyo Yamazaki, Takao Ikenoue, Nobuo Kondo, Wataru Miyanaga, Masaru Takayanagi
  • Patent number: 7928101
    Abstract: The present invention provides a fused polycyclic compound of the following formula, analogues thereof and pharmaceutically acceptable salts thereof; and agents for increasing the sugar-transporting capacity, hypoglycemic agents and pharmaceutical compositions containing the above compounds. This fused polycyclic compound has high medicinal properties and few side-effects, and a therapeutic effect on diabetes. wherein R represents an alkoxy group, R? represents an oxazolylpropionyl group or a thiazolylpropionyl group, and R? represent a hydrogen atom.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: April 19, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ryusuke Hirama, Seiji Niwa, Hideyuki Tanaka, Toshihiro Hatanaka, Yoko Masuzawa, Akiyo Yamazaki, Takao Ikenoue, Nobuo Kondo, Wataru Miyanaga, Masaru Takayanagi
  • Patent number: 7834006
    Abstract: The following fused polycyclic compound, analogues thereof or pharmaceutically acceptable salts thereof have an effect of increasing the sugar-transporting capacity and an effect of lowering the blood glucose level and, therefore, they are useful for preventing and/or treating diabetes and the like. wherein R is a methoxy group, Y is a (2-thiazolyl)-2-ethylcarbonyl group, R10 and R13 are hydrogen atoms, and R11 and R12 are methyl groups.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: November 16, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ryusuke Hirama, Hideyuki Tanaka, Seiji Niwa, Akiyo Yamazaki, Takao Ikenoue, Koji Ohsumi
  • Patent number: 7632830
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: December 15, 2009
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki, Seiji Niwa, Takashi Yamamoto
  • Publication number: 20080096862
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Application
    Filed: November 30, 2007
    Publication date: April 24, 2008
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yukio IINO, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki, Seiji Niwa, Takashi Yamamoto
  • Patent number: 7326701
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: February 5, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki, Seiji Niwa, Takashi Yamamoto
  • Patent number: 7153850
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Grant
    Filed: June 2, 2003
    Date of Patent: December 26, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki, Seiji Niwa, Takashi Yamamoto
  • Publication number: 20060258637
    Abstract: The following fused polycyclic compound, analogues thereof or pharmaceutically acceptable salts thereof have an effect of increasing the sugar-transporting capacity and an effect of lowering the blood glucose level and, therefore, they are useful for preventing and/or treating diabetes and the like. wherein R is a methoxy group, Y is a (2-thiazolyl)-2-ethylcarbonyl group, R10 and R13 are hydrogen atoms, and R11 and R12 are methyl groups.
    Type: Application
    Filed: July 14, 2006
    Publication date: November 16, 2006
    Applicant: AJINOMOTO CO. INC
    Inventors: Ryusuke Hirama, Hideyuki Tanaka, Seiji Niwa, Akiyo Yamazaki, Takao Ikenoue, Koji Ohsumi
  • Publication number: 20060194789
    Abstract: The present invention provides a fused polycyclic compound of the following formula, analogues thereof and pharmaceutically acceptable salts thereof; and agents for increasing the sugar-transporting capacity, hypoglycemic agents and pharmaceutical compositions containing the above compounds. This fused polycyclic compound has high medicinal properties and few side-effects, and a therapeutic effect on diabetes. wherein R represents an alkoxy group, R? represents an oxazolylpropionyl group or a thiazolylpropionyl group, and R? represent a hydrogen atom.
    Type: Application
    Filed: May 1, 2006
    Publication date: August 31, 2006
    Applicant: Ajinomoto Co., Inc.
    Inventors: Ryusuke Hirama, Seiji Niwa, Hideyuki Tanaka, Toshihiro Hatanaka, Yoko Masuzawa, Akiyo Yamazaki, Takao Ikenoue, Nobuo Kondo, Wataru Miyanaga, Masaru Takayanagi
  • Publication number: 20060189597
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Application
    Filed: April 6, 2006
    Publication date: August 24, 2006
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yukio Ilno, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki, Seiji Niwa, Takashi Yamamoto
  • Publication number: 20040048847
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Application
    Filed: June 2, 2003
    Publication date: March 11, 2004
    Applicant: AJINOMOTO CO. INC
    Inventors: Yukio Iino, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki