Abstract: A dual chamber syringe facilitates selective drug mixing, dosing, and administration through catheters or other vascular accessing devices (VADs), as well as pre- or post-administration flushing of catheters with a single syringe instrument. A syringe barrel incorporates an outlet, such as a Luer connector, variable-volume, axially tandem primary and secondary fluid chambers, with nested respective plungers, plunger rods capable of selective translation within the barrel interior along a common axis, and plunger stoppers. The secondary fluid chamber is incorporated within the primary plunger. A selectively resealable valve disposed within the barrel interior, selectively isolates the secondary fluid chamber from fluid communication with the primary fluid chamber and/or the outlet of the syringe barrel. In some embodiments, the valve is a duckbill-type valve or an umbrella valve. In some embodiments, the syringe is prepackaged with flushing solution in the secondary fluid chamber.

Abstract: Pump assemblies for use with an IV set are described herein. A pump assembly includes a rotatable crank, a piston rod, and a diaphragm assembly. The crank includes a crank profile defining a plurality of lobes. The piston rod includes a first follower and a second follower spaced apart from the first follower. The rotation of the crank relative to the piston rod causes the piston rod to reciprocate relative to the crank. The diaphragm assembly includes a housing and a diaphragm member. The diaphragm member is coupled to the housing and cooperatively defines a volume in fluid communication with the IV set. The diaphragm member is movable between an extended position configured to draw in fluid from the IV set and a contracted position configured to expel fluid into the IV set. The diaphragm member is coupled to the piston rod to reciprocate the diaphragm member.