Patents by Inventor Akshay Vaishnaw

Akshay Vaishnaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
    Patent number: 9339513
    Abstract: This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a liquid particle formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as endometrial cancer.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: May 17, 2016
    Assignee: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Jared Gollob, Akshay Vaishnaw, Christina Gamba-Vitalo, Dinah Wen-Yee Sah
  • Methods and compositions for prevention or treatment of RSV infection
    Patent number: 9127277
    Abstract: Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 8, 2015
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Akshay Vaishnaw, Saraswathy V. Nochur, Sayda Elbashir, Muthiah Manoharan, Rachel Meyers
  • Lipid Formulated Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes
    Publication number: 20140336243
    Abstract: This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as cancer.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 13, 2014
    Inventors: David Bumcrot, Dinah Wen-Yee Sah, Ivanka Toudjarska, Jared Gollob, Akshay Vaishnaw, Christina Gamba-Vitalo
  • Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
    Patent number: 8859516
    Abstract: This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as cancer.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: October 14, 2014
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: David Bumcrot, Dinah Wen-Yee Sah, Ivanka Toudjarska, Jared Gollob, Akshay Vaishnaw, Christina Gamba-Vitalo
  • LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF EG5 AND VEGF GENES
    Publication number: 20130345286
    Abstract: This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a liquid particle formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as endometrial cancer.
    Type: Application
    Filed: November 9, 2011
    Publication date: December 26, 2013
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Jared Gollob, Akshay Vaishnaw, Christina Gamba-Vitalo
  • Methods And Compositions For Prevention Or Treatment Of RSV Infection
    Publication number: 20130165499
    Abstract: Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets.
    Type: Application
    Filed: February 27, 2013
    Publication date: June 27, 2013
    Inventors: Akshay Vaishnaw, Saraswathy V. Nochur, Sayda Elbashir, Muthiah Manoharan, Rachel Meyers
  • Methods and compositions for prevention or treatment of RSV infection
    Patent number: 8410073
    Abstract: Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: April 2, 2013
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Akshay Vaishnaw, Saraswathy V. Nochur, Sayda Elbashir, Muthiah Manoharan, Rachel Meyers
  • Lipid Formulated Compositions And Methods For Inhibiting Expression Of Eg5 And VEGF Genes
    Publication number: 20120282341
    Abstract: This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as cancer.
    Type: Application
    Filed: September 10, 2010
    Publication date: November 8, 2012
    Inventors: David Bumcrot, Dinah Wen-Yee Sah, Ivanka Toudjarska, Jared Gollob, Akshay Vaishnaw, Christina Gamba-Vitalo
  • METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF RSV INFECTION
    Publication number: 20120189555
    Abstract: Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.
    Type: Application
    Filed: January 26, 2012
    Publication date: July 26, 2012
    Inventors: Akshay Vaishnaw, Saraswathy V. Nochur, Sayda Elbashir, Muthiah Manoharan, Rachel Meyers
  • Methods of treating viral disorders
    Patent number: 7662921
    Abstract: Methods of treating viral disorders are disclosed.
    Type: Grant
    Filed: May 9, 2005
    Date of Patent: February 16, 2010
    Assignee: Astellas US LLC
    Inventors: Burt Adelman, Akshay Vaishnaw
  • METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF RSV INFECTION
    Publication number: 20090238772
    Abstract: Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.
    Type: Application
    Filed: December 15, 2008
    Publication date: September 24, 2009
    Applicant: Alnylam Pharmaceuticals, Inc.
    Inventors: Akshay Vaishnaw, Saraswathy V. Nochur, Sayda Elbashir, Muthiah Manoharan, Rachel Meyers
  • Methods of Treating Viral Disorders
    Publication number: 20080019960
    Abstract: Methods of treating viral disorders are disclosed.
    Type: Application
    Filed: May 9, 2005
    Publication date: January 24, 2008
    Applicant: ASTELLAS US LLC
    Inventors: Burt Adelman, Akshay Vaishnaw
  • Methods for treating or preventing skin disorders using CD2-binding agents
    Publication number: 20070031443
    Abstract: Methods for treating or preventing an epidermal or dermal disorder, e.g., psoriasis, using a CD2-binding agent, e.g., an inhibitor of the CD2/LFA-3 interaction (e.g., an LFA-3/IgG fusion polypeptide), in combination with an auxiliary agent, e.g., UVB irradiation, are disclosed.
    Type: Application
    Filed: December 20, 2005
    Publication date: February 8, 2007
    Inventors: Akshay Vaishnaw, Kevin Cooper, Daniel Shrager, Thomas McCormick