Patents by Inventor Alain Alcade

Alain Alcade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMORPHIC FORM OF RIMONABANT, METHOD FOR PREPARING IT AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
    Publication number: 20100190827
    Abstract: The present invention relates to a novel crystalline polymorph of rimonabant, its method of preparation and the pharmaceutical compositions containing this novel polymorph.
    Type: Application
    Filed: October 28, 2008
    Publication date: July 29, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Alain ALCADE, Gilles Anne-Archard, Corinne Gavory, Olivier Monnier
  • Method for preparing 4-amino-4-phenylpiperidines
    Patent number: 7045630
    Abstract: The invention relates to a process for preparing a 4-amino-4-phenylpiperidine (I): in which R is hydrogen or a (C1–C3)alkyl group, characterized in that a 1-protected 4-piperidone (II): in which Pr? represents a removable N-protecting group, is treated sequentially first with an alkali metal cyanide and then with an amine ENHPr? (III) in which E represents a group R?=(C1–C3)alkyl, or an N-protecting group and Pr? is an N-protecting group, the protecting group(s) being removable under the same conditions as Pr?; then the compound thus obtained (IV) is subjected to a Grignard reaction with a phenylmagnesium halide, the two or three protecting groups are removed from the compound thus obtained (V) and compound (I) is isolated or in the form of the free base, which is converted into one of its salts.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: May 16, 2006
    Assignee: Sanofi-aventis
    Inventors: Alain Alcade, Gilles Anne-Archard, Daniel Capraro
  • Crystalline forms of osanetant
    Patent number: 7041679
    Abstract: The invention relates to crystalline forms of (R)-(+)-N-[[3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4-yl]-N-methylacetamide and to processes for preparing them.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: May 9, 2006
    Assignee: sanofi-aventis
    Inventors: Alain Alcade, Gilles Anne-Archard, Patrick Gros-Claude, Olivier Monnier, Jérome Roche
  • Polymorphic form of rimonabant method for preparing it and pharmaceutical compositions containing it
    Publication number: 20050043356
    Abstract: The present invention relates to a novel crystalline polymorph of rimonabant, its method of preparation and the pharmaceutical compositions containing this novel polymorph.
    Type: Application
    Filed: November 4, 2002
    Publication date: February 24, 2005
    Inventors: Alain Alcade, Gilles Anne-Archard, Corinne Gavory, Olivier Monnier
  • Method for preparing 4-amino-4-phenylpiperidines
    Publication number: 20040171837
    Abstract: The invention relates to a process for preparing a 4-amino-4-phenylpiperidine (I): 1
    Type: Application
    Filed: January 12, 2004
    Publication date: September 2, 2004
    Inventors: Alain Alcade, Gilles Anne-Archard, Daniel Capraro
  • Crystalline forms of osanetant
    Publication number: 20040044215
    Abstract: The invention relates to crystalline forms of (R)-(+)-N-[[3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4-yl]-N-methylacetamide and to processes for preparing them.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 4, 2004
    Inventors: Alain Alcade, Gilles Anne-Archard, Patrick Gros-Claude, Olivier Monnier, Jerome Roche