Patents by Inventor Alain Berdeaux

Alain Berdeaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10322162
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: June 18, 2019
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), COLLEGE DE FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), ECOLE NATIONALE VETERINAIRE D'ALFORT (ENVA)
    Inventors: St├ęphane Germain, Alain Berdeaux, Renaud Tissier, Bijan Ghaleh-Marzban, Catherine Monnot, Ariane Galaup
  • Publication number: 20180000892
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
    Type: Application
    Filed: January 6, 2016
    Publication date: January 4, 2018
    Inventors: St├ęphane GERMAIN, Alain BERDEAUX, Renaud TISSIER, Bijan GHALEH-MARZBAN, Catherine MONNOT, Ariane GALAUP
  • Publication number: 20170313751
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: July 18, 2017
    Publication date: November 2, 2017
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Stephane Germain, Ariane Galaup, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux
  • Patent number: 9439804
    Abstract: Method for treatment of a body of a mammal in cardiac arrest, comprising the step of performing a therapeutic hypothermia of the body after the cardiac arrest has occurred, said therapeutic hypothermia comprising: cooling the body to a target temperature during a cooling time period, said cooling being performed by total liquid ventilation which comprises alternately filling lungs of the body with a cooling liquid and removing from the lungs said cooling liquid, maintaining the body at the target temperature for a hypothermia duration.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: September 13, 2016
    Inventors: Renaud Tissier, Alain Berdeaux
  • Publication number: 20150353618
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 10, 2015
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Stephane Germain, Galaup Ariane, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux
  • Publication number: 20130023473
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: January 19, 2011
    Publication date: January 24, 2013
    Inventors: Stephane Germain, Ariane Galaup, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux
  • Publication number: 20120226337
    Abstract: Method for treatment of a body of a mammal in cardiac arrest, comprising the step of performing a therapeutic hypothermia of the body after the cardiac arrest has occurred, said therapeutic hypothermia comprising: cooling the body to a target temperature during a cooling time period, said cooling being performed by total liquid ventilation which comprises alternately filling lungs of the body with a cooling liquid and removing from the lungs said cooling liquid, maintaining the body at the target temperature for a hypothermia duration.
    Type: Application
    Filed: March 3, 2011
    Publication date: September 6, 2012
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Renaud Tissier, Alain Berdeaux
  • Patent number: 5591758
    Abstract: Organic nitrates, processes for their preparation and their use in the treatment of vascular diseases and in particular in the treatment of angina.The said nitrates correspond to the following formula I:R--CO--(A).sub.n --Y--B (I)in which:R represents, in particular, a sulphur-containing radical and a sulphur-containing amino acid residue; A represents, in particular, a CH.sub.2 group or a substituted amino acid; n is 0 or 1 or greater than 1; Y represents an oxygen atom or an NH group and B represents, in particular, a 1,4:3,6-dianhydro hexitol mononitrate radical, an itol nitrate radical or an inositol radical.The said organic nitrates are prepared by reacting:I. either a thio acid of the type R--COOH, in which R has the same meaning as above, with a derivative of formula II: (A).sub.n --Y--B, in which A, Y, B and n have the same meaning as above,II. or a derivative of formula III: R--CO--(A).sub.
    Type: Grant
    Filed: May 4, 1993
    Date of Patent: January 7, 1997
    Assignee: Laboratoires Hoechst, SA
    Inventors: Jean-Pierre Nallet, Jacques Dreux, Alain Berdeaux, Vincent Richard, Piero Martorana, Helmut Bohn