Patents by Inventor Alain Braun

Alain Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors
    Patent number: 9675606
    Abstract: The invention relates to the compounds of general formula (I): Preparation process and therapeutic use.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: June 13, 2017
    Assignee: SANOFI
    Inventors: Alain Braun, Olivier Duclos, Gilbert Lassalle, Franz Lorge, Valerie Martin, Olaf Ritzeler, Aurelie Strub
  • 2-AMINO-3-(IMIDAZOL-2-YL)-PYRIDIN-4-ONE DERIVATIVES AND THEIR USE AS VEGF RECEPTOR KINASE INHIBITORS
    Publication number: 20150328205
    Abstract: The invention relates to the compounds of general formula (I): Preparation process and therapeutic use.
    Type: Application
    Filed: July 24, 2015
    Publication date: November 19, 2015
    Inventors: Alain BRAUN, Olivier DUCLOS, Gilbert LASSALLE, Franz LORGE, Valerie MARTIN, Olaf RITZELER, Aurelie STRUB
  • 2-amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors
    Patent number: 9126972
    Abstract: The invention relates to the compounds of general formula (I): Preparation process and therapeutic use.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: September 8, 2015
    Assignee: SANOFI
    Inventors: Alain Braun, Olivier Duclos, Gilbert Lassalle, Franz Lorge, Valerie Martin, Olaf Ritzeler, Aurelie Strub
  • Pyrimidooxazocine derivatives as mTOR-inhibitors
    Patent number: 9120812
    Abstract: The invention relates to bicyclic heterocyclic derivatives of general formula (I) to a process for preparing them and to the therapeutic use thereof.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: September 1, 2015
    Assignee: Sanofi
    Inventors: Alain Braun, Olivier Crespin, Yann Foricher, Gilbert Marciniak, Nicolas Muzet, Eric Nicolai, Cecile Pascal, Bertrand Vivet, Fabrice Viviani
  • PYRIMIDOOXAZOCINE DERIVATIVES AS MTOR - INHIBITORS
    Publication number: 20140378433
    Abstract: The invention relates to bicydic heterocyclic derivatives of general formula (I) to a process for preparing them and to the therapeutic use thereof.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 25, 2014
    Applicant: SANOFI
    Inventors: Alain Braun, Olivier Crespin, Yann Foricher, Gilbert Marciniak, Nicolas Muzet, Eric Nicolai, Cecile Pascal, Bertrand Vivet, Fabrice Viviani
  • 2-AMINO-3-(IMIDAZOL-2-YL)-PYRIDIN-4-ONE DERIVATIVES AND THEIR USE AS VEGF RECEPTOR KINASE INHIBITORS
    Publication number: 20140094488
    Abstract: The invention relates to the compounds of general formula (I): Preparation process and therapeutic use.
    Type: Application
    Filed: May 16, 2012
    Publication date: April 3, 2014
    Applicant: SANOFI
    Inventors: Alain BRAUN, Olivier DUCLOS, Gilbert LASSALLE, Franz LORGE, Valerie MARTIN, Olaf RITZELER, Aurelie STRUB
  • Substituted quinoxalines, their preparation and their therapeutical use as 11?HSD1 modulators
    Patent number: 7947834
    Abstract: The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11?-HSD1 is involved.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: May 24, 2011
    Assignee: Sanofi-Aventis
    Inventors: Alain Braun, Patrick Mougenot, Claudie Namane, Eric Nicolai, Francois Pacquet, Christophe Philippo, Olivier Venier, Olivier Crespin, Cecile Pascal, Michel Aletru, Stefan Gussregen
  • Aminotropane derivatives, preparation thereof and therapeutic use thereof
    Patent number: 7569582
    Abstract: The present invention relates to compounds of formula (I) as defined herein that are melanocortin receptor agonists, to the preparation thereof and to the therapeutic use thereof in the treatment and in the prevention of obesity, diabetes and sexual dysfunctions that can affect both sexes, in the treatment of cardiovascular diseases, and also in anti-inflammatory uses or in the treatment of alcohol dependency.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: August 4, 2009
    Assignee: Sanofi-Aventis
    Inventors: Alain Braun, Bruno Cornet, Gilles Courtemanche, Olivier Crespin, Cecile Pascal
  • DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE
    Publication number: 20090176775
    Abstract: The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11?-HSD1 is involved.
    Type: Application
    Filed: December 18, 2008
    Publication date: July 9, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Alain BRAUN, Patrick MOUGENOT, Claudie NAMANE, Eric NICOLAI, Francois PACQUET, Christophe PHILIPPO, Olivier VENIER, Olivier CRESPIN, Cecile PASCAL, Michel ALETRU, Stefan GUSSREGEN
  • AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20070191364
    Abstract: The present invention relates to compounds of formula (I) as defined herein that are melanocortin receptor agonists, to the preparation thereof and to the therapeutic use thereof in the treatment and in the prevention of obesity, diabetes and sexual dysfunctions that can affect both sexes, in the treatment of cardiovascular diseases, and also in anti-inflammatory uses or in the treatment of alcohol dependency.
    Type: Application
    Filed: January 25, 2007
    Publication date: August 16, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Alain BRAUN, Bruno CORNET, Gilles COURTEMANCHE, Olivier CRESPIN, Eykmar FETT, Cecile PASCAL
  • AMINOTROPANE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20070191361
    Abstract: The present invention relates to compounds of formula (I) as defined herein that are melanocortin receptor agonists, to the preparation thereof and to the therapeutic use thereof in the treatment and in the prevention of obesity, diabetes and sexual dysfunctions that can affect both sexes, in the treatment of cardiovascular diseases, and also in anti-inflammatory uses or in the treatment of alcohol dependency.
    Type: Application
    Filed: January 25, 2007
    Publication date: August 16, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Alain BRAUN, Bruno CORNET, Gilles COURTEMANCHE, Olivier CRESPIN, Cecile PASCAL
  • OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20070149562
    Abstract: The present invention relates to compounds of formula (I) as defined herein that are melanocortin receptor agonists, to the preparation thereof and to the therapeutic use thereof in the treatment or prevention of a condition selected from obesity, diabetes and sexual dysfunctions that can affect both sexes, in the treatment of cardiovascular diseases, and also in anti-inflammatory uses or in the treatment of alcohol dependency.
    Type: Application
    Filed: January 25, 2007
    Publication date: June 28, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Alain Braun, Gilles Courtemanche, Olivier Crespin, Eykmar Fett, Cecile Pascal
  • 2-arylquinoline derivatives, preparation and therapeutic use thereof
    Patent number: 6617336
    Abstract: Compounds of general formula (I) in which: A represents a hydrogen atom, a hydroxyl, a C1-3 alkoxy group, a hydroxy(C1-6 alkyl) group, a (C1-3 alkoxy)(C1-3 alkyl) group, a thiol, (C1-6 alkyl)sulfanyl or a halogen; B and D represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or B and D together from an oxo; R1 represents a phenyl, a naphthyl or a heteroaryl comprising 4 or 5 carbon atoms; R2 and R3 represent, independently of one another, a hydrogen atom, a halogen or a C1-6 alkyl group, R4 represents a hydrogen atom, a hydroxyl or a halogen, and R5 and R6 represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C3-6 cycloalkyl group, a C3-6 cycloalkenyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or R5 and R6 together form a C2-6 alkylene chain or a C3-6 alkenylene chain, to give, with the nitrogen to which they are attached, a heteroc
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: September 9, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Philippe R Bovy, Alain Braun, Christophe Philippo
  • 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof
    Publication number: 20030097000
    Abstract: Compounds of general formula (I) 1
    Type: Application
    Filed: June 14, 2002
    Publication date: May 22, 2003
    Inventors: Philippe R. Bovy, Alain Braun, Christophe Philippo
  • 8-(heterocyclylmethyl)quinoline derivatives for treating urinary incontinence
    Patent number: 6413984
    Abstract: The invention concerns compounds of formula (I) wherein: A represents either a hydrogen atom or a hydroxyl group; B represents a pyrrolidin-2-yl (D) or 2-piperidyl (E), B capable of being substituted by one or two R5 groups; R1 represents a hydrogen atom, a C1-C6 alkyl, a C2-C6 alkenyl, a C1-C2 perfluoroalkyl or a C1-C6 fluoroalkyl group; R2, R3 or R4, independently of one another, represent a hydrogen atom, a C1-C6 alkyl, group or a C2-C6 alkenyl group, or R1 and R2 can together form a C1-C6 alkylene chain, or a C3-C6 alkenylene chain; R5 represents a C1-C6 alkyl group, and R6 represents a hydrogen atom, a C1-C6 alkyl group, a C2-C6 alkenyl group, C3-C6 cycloalkyl, C3-C6 cycloalkenyl or a benzyl.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: July 2, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Christophe Philippo, Alain Braun, Philippe R. Bovy
  • 1-aminoethylquinoline derivatives for treating urinary incontinence
    Patent number: 6331549
    Abstract: The invention relates to 1-aminoethylquinoline derivatives, to pharmaceutical compositions containing them, to therapeutic methods of using them and to processes for preparing them.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: December 18, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Christophe Philippo, Patrick Mougenot, Gérard Defosse, Alain Braun, Philippe Bovy