Patents by Inventor Alain Cuine
Alain Cuine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230414604Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: April 28, 2023Publication date: December 28, 2023Applicant: Fresenius Kabi Deutschland GmbHInventors: Alain CUINE, Didier HOARAU, Pauline ROMAIN
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Publication number: 20200345720Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: March 18, 2020Publication date: November 5, 2020Applicant: Fresenius Kabi Deutschland GmbHInventors: Alain CUINE, Didier HOARAU, Pauline ROMAIN
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Publication number: 20190167665Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: February 11, 2019Publication date: June 6, 2019Applicant: Fresenius Kabi Deutschland GmbHInventors: Alain CUINE, Didier HOARAU, Pauline ROMAIN
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Patent number: 10213424Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: GrantFiled: October 20, 2015Date of Patent: February 26, 2019Assignee: Fresenius Kabi Deutschland GmbHInventors: Alain Cuine, Didier Hoarau, Pauline Romain
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Publication number: 20160175297Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: October 20, 2015Publication date: June 23, 2016Inventors: Alain CUINE, Didier HOARAU, Pauline ROMAIN
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Patent number: 9192608Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: GrantFiled: May 18, 2015Date of Patent: November 24, 2015Assignee: BECTON DICKINSON FRANCE S.A.S.Inventors: Alain Cuine, Didier Hoarau, Pauline Romain
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Publication number: 20150246036Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: May 18, 2015Publication date: September 3, 2015Inventors: Alain CUINE, Didier HOARAU, Pauline ROMAIN
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Patent number: 9072781Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: GrantFiled: March 12, 2014Date of Patent: July 7, 2015Assignee: Becton, Dickinson France S.A.S.Inventors: Alain Cuine, Didier Hoarau, Pauline Romain
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Publication number: 20140275144Abstract: Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: Becton Dickinson France S.A.S.Inventors: Alain CUINE, Didier Hoarau, Pauline Romain
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Publication number: 20100291204Abstract: The invention relates to the combination of: a short-acting hypnotic agent which is selected from among a modulators of receptors GABA-A, a benzodiazepine, a phenothiazine, a melatonin derivative and a melatonin receptor agonist; and a long-acting hypnotic agent which is selected from among a modulator of receptors GABA-A, a benzodiazepine, an antagonist of receptors 5HT2A and a calcium ion modulator, for the treatment of sleep disorders. The invention also relates to galenic formulations containing said combinations.Type: ApplicationFiled: July 29, 2010Publication date: November 18, 2010Applicant: SANOFI-AVENTISInventors: Alain CUINE, Michel DECOBERT, Dominique FRANCON, Henry SAUNAL
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Publication number: 20080181943Abstract: The invention relates to the combination of: a short-acting hypnotic agent which is selected from among a modulators of receptors GABA-A, a benzodiazepine, a phenothiazine, a melatonin derivative and a melatonin receptor agonist; and a long-acting hypnotic agent which is selected from among a modulator of receptors GABA-A, a benzodiazepine, an antagonist of receptors 5HT2A and a calcium ion modulator, for the treatment of sleep disorders. The invention also relates to galenic formulations containing said combinations.Type: ApplicationFiled: February 11, 2008Publication date: July 31, 2008Applicant: SANOFI-AVENTISInventors: Alain CUINE, Michel DECOBERT, Dominique FRANCON, Henry SAUNAL
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Publication number: 20070190146Abstract: The present invention relates to a pharmaceutical controlled release multilayer tablet comprising at least two layers, at least one active ingredient with highly pH-dependent solubility, at least one pharmaceutically acceptable pH maintaining excipient and at least one pharmaceutically acceptable matrix forming excipient, characterized in that said at least one active ingredient with highly pH-dependent solubility and said at least one pharmaceutically acceptable pH maintaining excipient are respectively comprised in at least one distinct layer.Type: ApplicationFiled: January 11, 2007Publication date: August 16, 2007Applicant: sanofi-aventisInventors: Benedicte Roger, Jean Bruel, Alain Cuine
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Patent number: 6861072Abstract: The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterized in that it comprises two or three layers and contains (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.Type: GrantFiled: October 12, 1999Date of Patent: March 1, 2005Assignee: Sanofi-SynthelaboInventors: Gérard Alaux, Frédéric Andre, Alain Cuine, Gareth Lewis
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Patent number: 6069165Abstract: A pharmaceutical composition, comprising a lipophilic phase and, as active principle, at least one compound selected froman optically active isomer or a racemate of amisulpride;an optically active isomer or a racemate of a pharmaceutically acceptable acid addition salt of amisulpride;an optically active isomer or a racemate of a quaternary ammonium salt of amisulpride; andan optically active isomer or a racemate of an oxide of amisulpride.Type: GrantFiled: March 16, 1999Date of Patent: May 30, 2000Assignee: SynthelaboInventors: Veronique Andrieu, Alain Cuine, Jean Montel
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Patent number: 5672356Abstract: Bioadhesive pharmaceutical composition for the controlled release of active principles locally across the buccal cavity or systemically across a mucous membrane, wherein it is composed of an active principle, a compound (A), a compound (B) and excipients as defined in the description.Type: GrantFiled: September 21, 1994Date of Patent: September 30, 1997Assignee: Adir et CompagnieInventors: Isabelle Rault, Gerald Pichon, Alain Cuine
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Patent number: 5431902Abstract: New medicament aerosol formulation based on fusafungine comprising excipient which is either dimethyl isosorbide or preferably, isopropyl myristate, and using as propellant 1,1,1,2-tetrafluoroethane.Type: GrantFiled: May 12, 1994Date of Patent: July 11, 1995Assignee: Adir et CompagnieInventors: Alain Cuine, Serge Morisseau
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Patent number: 5334392Abstract: The invention relates to a matrix tablet for the sustained release of indapamide which ensures a continuous and uniform release of the active principle after oral administration.Type: GrantFiled: June 9, 1992Date of Patent: August 2, 1994Assignee: Adir et CompagnieInventors: Alain Cuine, Bruno H. de Barochez, David Guez
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Patent number: 4753352Abstract: New impervious single packaging in the form of a card having compartments and permitting gaseous exchange between the compartments, of which one or more are designed to contain a gas absorber or generator and the others act as receptacles for the solid bodies to be stored; the said compartments being interconnected by small channels.This safety packaging is particularly suited to use in the storage of solid pharmaceutical bodies (tablets, capsules or others).Type: GrantFiled: May 23, 1986Date of Patent: June 28, 1988Assignee: ADIR et CompagnieInventors: Jacques Dauphin, Alain Cuine