Patents by Inventor Alain Faivre-Chauvet

Alain Faivre-Chauvet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR RADIOIODINATION OR RADIOASTATINATION OF A BIOMOLECULE
    Publication number: 20220220043
    Abstract: The present invention relates to a method for radioiodination or radioastatination of a biomolecule such as proteins and antibodies by reacting a biomolecule carrying a hetero(aryl) boronic acid group with a radioiodide or astatide salt, in the presence of a catalyst and a ligand, in a buffer solution, in order to obtain a radioiodo- or astatolabeled biomolecule. The method of the invention is thus a single step method easy to be implemented and efficient for both radioiodination and radioastatination of antibodies.
    Type: Application
    Filed: April 28, 2020
    Publication date: July 14, 2022
    Inventors: Marion BERDAL, François GUERARD, Jean-François GESTIN, Alain FAIVRE-CHAUVET
  • Ionic liquid supported organotin reagents for the manufacturing of radiopharmaceuticals compounds
    Patent number: 9714261
    Abstract: An ionic liquid supported organotin reagent of formula (I) A process for manufacturing the ionic liquid supported organotin reagent of formula (I), a process for manufacturing an halogenated or radio-halogenated compound using compound of formula (I), a device for implementing the halogenating process and a kit including the compound of formula (I) are also described.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: July 25, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE NANTES, UNIVERSITE D' ANGERS, UNIVERSITE DU MAINE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
    Inventors: Stephanie Legoupy, Djibril Faye, Jean-Francois Gestin, Holisoa Rajerison, Alain Faivre-Chauvet, Fabien Boeda
  • IONIC LIQUID SUPPORTED ORGANOTIN REAGENTS FOR THE MANUFACTURING OF RADIOPHARMACEUTICALS COMPOUNDS
    Publication number: 20160326194
    Abstract: An ionic liquid supported organotin reagent of formula (I) A process for manufacturing the ionic liquid supported organotin reagent of formula (I), a process for manufacturing an halogenated or radio-halogenated compound using compound of formula (I), a device for implementing the halogenating process and a kit including the compound of formula (I) are also described.
    Type: Application
    Filed: January 7, 2015
    Publication date: November 10, 2016
    Inventors: Stephanie LEGOUPY, Djibril FAYE, Jean-Francois GESTIN, Holisoa RAJERISON, Alain FAIVRE-CHAUVET, Fabien BOEDA
  • Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof
    Patent number: 9290421
    Abstract: The present invention relates to a compound having formula (I): wherein: —X is in particular 125I Or 211At; —R1 and R?1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R5, R8 and R9 are preferably H; —Y is preferably an electron withdrawing group.
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: March 22, 2016
    Assignees: Institut National de la Santé de la Recherche Medicalé, Université de Nantes, CHU Nantes
    Inventors: Jean-Francois Gestin, Francois Guerard, Alain Faivre-Chauvet
  • Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof
    Publication number: 20150139901
    Abstract: The present invention concerns radioactive rhodium complexes, their preparation methods, and their use for the radiolabelling of biomolecules, especially monoclonal antibodies.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 21, 2015
    Applicants: Institut National de la Sante et de la Recherche (INSERM), Chu Nantes, Universite de Nantes, Centre National de la Recherche Scientifique (C.N.R.S.), Universite d' Angers
    Inventors: Alain Faivre-Chauvet, Holisoa Rajaerison, Jean-Francois Gestin
  • HYPERVALENT RADIOACTIVE ASTATINE OR IODINE COMPOUNDS, AND PREPARATION METHODS THEREOF
    Publication number: 20130004420
    Abstract: The present invention relates to a compound having formula (I): wherein: X is in particular 125I Or 211At; R1 and R?1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; Z is a heteroatom, R5, R8 and R9 are preferably H; Y is preferably an electron withdrawing group.
    Type: Application
    Filed: February 20, 2011
    Publication date: January 3, 2013
    Inventors: Jean-Francois Gestin, Francois Guerard, Alain Faivre-Chauvet