Abstract: New 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols.The present invention relates to a 3-amino-4-nitrophenol of formula: ##STR1## where Z denotes --CH.sub.2 --W, W denoting hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalkoxy(C.sub.1 -C.sub.6)alkyl and R denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl or (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl, the process for preparation thereof and the intermediate compound of formula: ##STR2## in which Z' denotes CH.sub.2 --W, W denoting C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy-(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalcoxy(C.sub.1 -C.sub.6)alkyl.

Abstract: New dimethyl derivatives of 3-nitro-4-aminoaniline, process for their preparation, and their use for dyeing keratinic fibres.The invention relates to dimethyl derivatives of 3-nitro-4-aminoaniline of formula: ##STR1## in which CH.sub.3 is in position 2 or 5 of the benzene ring and R.sub.1 and R.sub.2 denote independently of each other a hydrogen atom, a lower alkyl group, a lower mono- or polyhydroxyalkyl or a lower aminoalkyl group in which the amino group is optionally mono- or disubstituted by a lower alkyl radical or by a lower mono- or polyhydroxyalkyl radical, it being understood that the two symbols R.sub.1 and R.sub.2 can be simultaneously other than hydrogen only when the mobile CH.sub.3 radical is in position 5, or cosmetically acceptable salts of these compounds, as well as the process for preparing them and their use in dye compositions, in particular for hair, equally for direct coloring and for coloring by an oxidation route.

Abstract: A series of syringe bodies with their lower ends closed is filled with a solution of medicine to a predetermined level in the bodies. The syringe bodies are placed in a lyophilizer with the bodies arranged in a predetermined pattern. A plurality of plungers for the syringe bodies is arranged in a corresponding pattern and above the syringe bodies. After the medicine in the syringe bodies is lyophilized in the lyophilizer, a reduced pressure is created in the lyophilizer and the plungers are simultaneously moved into the syringe bodies to a predetermined level above the lyophilized medicine. The pressure within the lyophilizer is then increased to atmospheric and the assembled syringes are removed. Apparatus for implementing the process can include a lower rack having openings for retaining the syringe bodies in the predetermined pattern, and an upper rack seatable on the lower rack for retaining the piston portions of plungers in facing relation to, aligned with, and above the openings of the syringe bodies.

Abstract: Process for the preparation in a series of self-injectable syringes characterized mainly by the fact that multiple seal tubes are placed vertically on an appropriate support, that a syringe body is placed vertically in each seal tube, that, into each tubular body thus arranged, a single dose of the medication in solution in a solvent is placed in each seal tube, above the syringe body, a plunger suspended by its pusher in a movable manner, at the lower end of a stopper which can adapt to the seal tube, so that said plunger is essentially in the axis of the syringe body and the lower end of said plunger is located above the upper end of the syringe body, with said stopper being held in a position so that said seal tube is not blocked or is not entirely blocked, to thus obtain an assembly constituting an open system in which the internal space, in the seal tubes and above said solution in the syringe bodies, is connected with the outside of the system, that the lyophilization operation is effected and, at this

Abstract: The invention relates to a dyeing composition for keratinous fibres containing at least one 4-bis(.beta.-hydroxyethyl)amino-2-nitro-1-(N-substituted amino)benzene compound in which the substitution is C.sub.1 -C.sub.3 alkyl or .beta.-hydroxyethyl; this composition contains as co-solubilization agent at least one dye of formula (II) ##STR1## in which formula: R.sub.2 denotes a C.sub.2 -C.sub.3 hydroxyalkyl group;R.sub.3 denotes a C.sub.2 -C.sub.3 hydroxyalkyl group; with the proviso that, if R.sub.3 =CH.sub.2 CH.sub.2 OH, R.sub.2 is necessarily an .alpha.-hydroxyethyl or hydroxypropyl radical.

Abstract: The invention provides a composition and process for directly dyeing keratinic fibres. The combination of 1-N-methylamino-2-nitro-4-N'-methyl-N'-(2' ,3'-dihydroxypropyl)amino benzene with certain 2-nitroparaphenylenediamine direct nitro dyes produces a dye composition in which the dyes can be more concentrated (without crystallizing out) and hence produce darker shades.