Patents by Inventor Alain Gobert

Alain Gobert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7442692
    Abstract: A compound selected from those of formula (I): wherein: R3 represents a hydrogen atom, and R1 and R2 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, or R1 represents a hydrogen atom, and R2 and R3 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, n represents 1 or 2, —X— represents a group selected from —(CH2)m—O-Ak-, —(CH2)m—NR4-Ak-, —(CO)—NR4-Ak- and —(CH2)m—NR4-(CO)—, m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4 represents a hydrogen atom or an alkyl group, Ar represents an aryl or heteroaryl group, its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: October 28, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Guillaume De Nanteuil, Bernard Portevin, Philippe Gloanec, Mark Millan, Jean-Claude Ortuno, Clotilde Mannoury La Cour, Alain Gobert
  • Publication number: 20060223830
    Abstract: A compound selected from those of formula (I): wherein: R3 represents a hydrogen atom, and R1 and R2 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, ?or R1 represents a hydrogen atom, and R2 and R3 together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted, n represents 1 or 2, —X— represents a group selected from —(CH2)m—O-Ak-, —(CH2)m—NR4-Ak-, —(CO)—NR4-Ak- and —(CH2)m—NR4-(CO)—, ?m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4 represents a hydrogen atom or an alkyl group, Ar represents an aryl or heteroaryl group, its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 5, 2006
    Inventors: Guillaume De Nanteuil, Bernard Portevin, Philippe Gloanec, Mark Millan, Jean-Claude Ortuno, Clotilde Mannoury La Cour, Alain Gobert
  • Patent number: 7053108
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 represents hydrogen, or R1 represents hydrogen, and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicaments.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: May 30, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6998403
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 and R4 represent hydrogen, or R1 and R4 represent hydrogen and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, or R1 and R2 represent hydrogen and R3 and R4 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, addition salts thereof with a pharmaceutically acceptable acid or base, and methods of treating conditions susceptible to ?2-AR/5-HT2C antagonists.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: February 14, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert, Benjamin Di Cara
  • Publication number: 20050059675
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 and R4 represent hydrogen, or R1 and R4 represent hydrogen and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, or R1 and R2 represent hydrogen and R3 and R4 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, addition salts thereof with a pharmaceutically acceptable acid or base, and methods of treating conditions susceptible to ?2-AR/5-HT2C antagonists.
    Type: Application
    Filed: August 25, 2004
    Publication date: March 17, 2005
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert, Benjamin Di Cara
  • Publication number: 20040192736
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: March 30, 2004
    Publication date: September 30, 2004
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6759421
    Abstract: A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, and R3 represents hydrogen, or R1 represents hydrogen, and R2 and R3 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifluoromethyl, its enantiomers, diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicaments.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: July 6, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Publication number: 20030199555
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: March 27, 2003
    Publication date: October 23, 2003
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Alain Gobert
  • Patent number: 6239129
    Abstract: Compound of formula (I): wherein: R1 and R2 each independently of the other represents hydrogen or alkyl, A represents alkylene, alkenylene or alkynylene, G1 represents wherein R3 and R4 each independently of the other represents hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, optionally substituted aryl or optionally substituted arylalkyl, or G1 represents heterocycloalkyl optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, nitrile, carboxy, alkoxycarbonyl, carbamoyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl or optionally substituted heteroarylalkyl, and which medicinal products containing the same/are useful as serotonin-reuptake inhibitors.
    Type: Grant
    Filed: January 25, 2000
    Date of Patent: May 29, 2001
    Assignee: Adir et Compagnie
    Inventors: Gilbert Lavielle, Olivier Muller, Bernard Cimetiere, Mark Millan, Alain Gobert, Jean-Michel Rivet
  • Patent number: 6127396
    Abstract: The invention relates to a compound of formula (I): ##STR1## wherein: A represents an optionally substituted benzene ring,B represents an imidazoline ring of formula (Ia) or (Ib): ##STR2## X represents CR.sup.6, CR.sup.6 R.sup.7, NR.sup.8, SO or SO.sub.2, or oxygen, nitrogen or sulphur,Y represents a single bond or CH or CH.sub.2,Z represents a carbon atom or CR.sup.4,R.sup.1, R.sup.2, R.sup.3, which may be the same or different, each represent hydrogen or alkyl, it being possible for (R.sup.1 and R.sup.4) or (R.sup.2 and R.sup.4) to form cyclopropane,R.sup.5 represents hydrogen, alkyl or benzyl.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: October 3, 2000
    Assignee: Adir et Compagnie
    Inventors: Alex Cordi, Jean-Michel Lacoste, Mark Millan, Adrian Newman-Tancredi, Alain Gobert
  • Patent number: 5968954
    Abstract: New 2-aminoindan compounds of formula: ##STR1## wherein: n, Ar, R, E, X.sub.1, X.sub.2, X.sub.3, and X.sub.4 are as defined in the description, in the form of a racemic mixture and in the form of optical isomers, and physiologically-tolerable acid addition salts thereof. The products of the invention are useful as medicaments and exhibit selective binding affinity for the 5HT.sub.1B receptors.
    Type: Grant
    Filed: February 26, 1998
    Date of Patent: October 19, 1999
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Alain Gobert
  • Patent number: 5965575
    Abstract: New N-arylpiperidine compounds of formula: ##STR1## wherein: A, m, R, E, n and Ar are as defined in the description, the isomers thereof and the addition salts thereof with a pharmaceutically acceptable acid, and medicinal products containing the same are useful in the treatment of disorders involving the serotininergic system.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 12, 1999
    Assignee: Adir Et Compagnie
    Inventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Alain Gobert, Valerie Audinot
  • Patent number: 5753662
    Abstract: A compound selected from those of formula: ##STR1## wherein: A--B, n, D and E are as defined in the specification, their racemic mixtures, and their optical isomers, and also the physiologically tolerable salts thereof with appropriate acids.The products of the invention may be used therapeutically.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: May 19, 1998
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Aimee Dessinges, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Alain Gobert
  • Patent number: 5684020
    Abstract: A compound selected from those of formula: ##STR1## wherein: A-B, n, D and E are as defined in the specification,their racemic mixtures, and their optical isomers,and also the physiologically tolerable salts thereof with appropriate acids.The products of the invention may be used therapeutically.
    Type: Grant
    Filed: January 30, 1997
    Date of Patent: November 4, 1997
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Aimee Dessinges, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Alain Gobert