Patents by Inventor Alain Le Ridant

Alain Le Ridant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100105666
    Abstract: Compounds of formula (I): wherein: R1 represents hydrogen, (C1-C6)alkyl, (C1-C6)aminoalkyl or (C1-C6)hydroxyalkyl, R2 represents hydrogen, or R1 and R2, together with the carbon atoms carrying them, form a carbon-carbon bond, R3 represents hydrogen, R4 represents hydrogen, methyl or (C3-C6)alkyl, (C1-C6)aminoalkyl, (C1-C6)hydroxyalkyl, aryl-(C1-C6)alkyl or heterocycloalkyl-(C1-C6)alkyl, or R3 and R4 together with the carbon atoms carrying them, form a carbon-carbon bond, R5, R6, R7 and R8 represent hydrogen, or a pair of geminal substituents (R5 and R6 and/or R7 and R8) form an oxo, thioxo or imino group, R9 represents hydrogen, halogen, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, cyano, nitro, (C1-C6)polyhaloalkyl or optionally substituted amino, R10 and R11 represent hydrogen, halogen, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy, cyano, nitro, (C1-C6)polyhaloalkyl or optionally substituted amino, n represents an integer between 0 and 4 inclusive, m represents an integer between 0 and 2 inclusive, p represents an
    Type: Application
    Filed: January 4, 2008
    Publication date: April 29, 2010
    Inventors: Jean-Daniel Brion, Maud Hervet, Anne Moreau, Zafiarisoa Dolor Renko, Alain Le Ridant, Catherine Harpey
  • Publication number: 20090298813
    Abstract: Use of neuroprotective compounds in obtaining medicaments intended for the curative treatment of neurodegenerative disease and/or the prevention of the appearance of disorders ensuing from those diseases.
    Type: Application
    Filed: January 4, 2008
    Publication date: December 3, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Alain Le Ridant, Catherine Harpey
  • Publication number: 20090258883
    Abstract: Compounds of formula (I): wherein: A represents a divalent radical: wherein: Z represents an oxygen atom or a sulphur atom, R6 represents a hydrogen atom, an alkyl, alkenyl, arylalkyl or polyhaloalkyl group or a substituted, linear or branched alkyl chain, represents a single bond or a double bond, R1, R2, R3 and R4 represent a hydrogen or halogen atom, an alkyl, alkoxy, hydroxy, cyano, nitro, polyhaloalkyl or optionally substituted amino group, or a linear or branched alkyl chain substituted by one or more groups, R5 represents a hydrogen atom or an alkyl, aminoalkyl or hydroxyalkyl group, X and Y represent a hydrogen atom or an alkyl group, Ra, Rb, Rc and Rd represent a hydrogen or halogen atom, an alkyl, hydroxy, alkoxy, cyano, nitro, polyhaloalkyl, optionally substituted amino group, or a substituted, linear or branched alkyl chain, Re represents a hydrogen atom or an alkyl, arylalkyl or alkenyl group or a substituted, linear or branched alkyl chain, their enantiomers, diastereoisomers
    Type: Application
    Filed: July 6, 2006
    Publication date: October 15, 2009
    Applicants: LES LABORATOIRES SERVIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD
    Inventors: Jean-Daniel Brion, Fabrice Bintein, Rodolphe Razet, Patrick Razon, Zafiarisoa Dolor Renko, Eric Levoirier, Jean-Francois Pujol, Dinah Weissmann, Alain Le Ridant, Catherine Harpey
  • Publication number: 20090176794
    Abstract: Compounds of formula (I): wherein: R1 and R2, which may be the same or different, represent a hydrogen atom or a linear or branched (C1-C6)alkyl group, R3 represents a hydrogen or halogen atom, a linear or branched (C1-C6)alkyl group, or a linear or branched (C1-C6)alkoxy group, Het represents a pyridyl, pyrimidinyl or piperidyl group, which are optionally substituted by one or more groups selected from halogen, linear or branched (C1-C6)alkyl and linear or branched (C1-C6)alkoxy, —represents a single bond or a double bond, their enantiomers and diastereoisomers, and also addition salts thereof with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful in the treatment of depression, anxiety, disorders of memory in the course of aging and/or neurodegenerative diseases, and in the palliative treatment of Parkinson's disease, and for adaptation to stress.
    Type: Application
    Filed: December 30, 2008
    Publication date: July 9, 2009
    Applicants: LES LABORATOIRES SERVIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD
    Inventors: Jean-Daniel Brion, Abdallah Deyine, Alain Le Ridant, Catherine Harpey
  • Patent number: 7339061
    Abstract: Compound of formula (I): wherein: R1, R2, R3, R4, R6, R8, R9 and R10, which may be the same or different, each represent a group selected from hydrogen, hydroxy, alkoxy, alkyl, arylalkoxy, alkoxycarbonylalkoxy and OR? wherein R? represents an ionised or ionisable group, R5 represents a group selected from alkyl, aryl and heteroaryl, R7 represents a group selected from hydrogen, hydroxy, alkoxy, alkyl and cycloalkyl, or R7 represents a nitrogen-containing or oxygen-containing heterocycle, its optical isomers, hydrates and solvates thereof and addition salts thereof, with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful as anti-cancer agents.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: March 4, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Daniel Brion, Lucien Israel, Alain Le Ridant, Catherine Harpey, Cherif Rabhi, El Bachir Kaloun
  • Publication number: 20060063801
    Abstract: Compound of formula (I): wherein: R1, R2, R3, R4, R6, R8, R9 and R10, which may be the same or different, each represent a group selected from hydrogen, hydroxy, alkoxy, alkyl, arylalkoxy, alkoxycarbonylalkoxy and OR? wherein R? represents an ionised or ionisable group, R5 represents a group selected from alkyl, aryl and heteroaryl, R7 represents a group selected from hydrogen, hydroxy, alkoxy, alkyl and cycloalkyl, or R7 represents a nitrogen-containing or oxygen-containing heterocycle, its optical isomers, hydrates and solvates thereof and addition salts thereof, with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful as anti-cancer agents.
    Type: Application
    Filed: June 18, 2003
    Publication date: March 23, 2006
    Inventors: Jean-Daniel Brion, Lucien Israel, Alain Le Ridant, Catherine Harpey, Cherif Rabhi, El Bachir Kaloun
  • Patent number: 6686360
    Abstract: The present invention relates to a compound selected from those of formula (I): wherein: R1 represents alkyl, R2 represents hydroxy, alkoxy, or amino, n represents an integer from 1 to 12 inclusive, R3 represents: hydrogen, optionally substituted alkyl, cycloalkyl, pyrimidinyl or optionally substituted phenyl, its isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, medicinal products containing the same are useful in the prevention or treatment of acute and chronic cell ischaemia.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: February 3, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Serge Labidalle, Jean-Paul Tillement, Bernard Testa, Roméo Cecchelli, Alain Le Ridant, Catherine Harpey, Michael Spedding, Esther Schenker
  • Publication number: 20030158207
    Abstract: The present invention relates to a compound selected from those of formula (I): 1
    Type: Application
    Filed: July 16, 2002
    Publication date: August 21, 2003
    Inventors: Serge Labidalle, Jean-Paul Tillement, Bernard Testa, Romeo Cecchelli, Alain Le Ridant, Catherine Harpey, Michael Spedding, Esther Schenker
  • Patent number: 5863925
    Abstract: The invention relates to the use of sulbutiamine and pharmaceutical compositions thereof for the treatment of Parkinson's Disease, Schizophrenia, alcoholism, and dysthymia.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: January 26, 1999
    Assignee: Adir et Compagnie
    Inventors: Helene Ollat, Alain Le Ridant, Laurent Perret
  • Patent number: 4765987
    Abstract: New artificial surfactants composed of dipalmitoylphosphatidylcholine, distearoylphosphatidylcholine and soya lecithin and pharmaceutical compositions containing them, which can be used to replace deficient endogenous pulmonary surfactant.
    Type: Grant
    Filed: August 25, 1986
    Date of Patent: August 23, 1988
    Assignee: ADIR & Cie
    Inventors: Frederic Bonte, Michel Dehan, Alain Le Ridant, Francis Puisieux, Christiane C. Taupin