Abstract: Behavioral profiling with actionable feedback methodologies and systems is provided. Benchmarking of profiles against empirical data can be utilized to determine areas of weakness in profiles or asymmetries relative to a benchmark. Feedback methodologies allow for optimization of individualized profiles and re-evaluation of behavioral profiling based on empirical data, as well as optimal profile grouping.

Abstract: Behavioral profiling with actionable feedback methodologies and systems is provided. Benchmarking of profiles against empirical data can be utilized to determine areas of weakness in profiles or asymmetries relative to a benchmark. Feedback methodologies allow for optimization of individualized profiles and re-evaluation of behavioral profiling based on empirical data, as well as optimal profile grouping.

Abstract: Behavioral profiling with actionable feedback methodologies and systems is provided. Benchmarking of profiles against empirical data can be utilized to determine areas of weakness in profiles or asymmetries relative to a benchmark. Feedback methodologies allow for optimization of individualized profiles and re-evaluation of behavioral profiling based on empirical data, as well as optimal profile grouping.

Abstract: Embodiments of the present disclosure are directed to behavioral profiling with actionable feedback methodologies and systems. Benchmarking of profiles against empirical data can be utilized to determine areas of weakness in profiles or asymmetries relative to a benchmark. Feedback methodologies allow for optimization of individualized profiles and re-evaluation of behavioral profiling based on empirical data, as well as optimal profile grouping.

Abstract: Dynamic crusher for treading fruit, particularly grapes, with a treading chamber having, when considering the direction of the path followed by the fruit in the crusher, an upstream fruit-introduction opening, a downstream discharge opening for discharging the must that results from the treading, a rotary ejector that allows kinetic energy to be imparted to the fruit introduced into the treading chamber, and allows the fruit to be cast against a fixed fruit-bursting wall, wherein the rotary ejector is mounted such that it can rotate about a vertical axis and a fixed fruit-bursting wall is positioned around the rotary ejector or facing the peripheral edge thereof against which fruit is cast, rotation of which allows the fruit to be cast, under the effect of centrifugal force, against the fixed fruit-bursting wall, causing the fruit to burst. A method for dynamically treading fruit using such a crusher is also disclosed.

Abstract: Embodiments of the present disclosure are directed to behavioral profiling with actionable feedback methodologies and systems. Benchmarking of profiles against empirical data can be utilized to determine areas of weakness in profiles or asymmetries relative to a benchmark. Feedback methodologies allow for optimization of individualized profiles and re-evaluation of behavioral profiling based on empirical data, as well as optimal profile grouping.

Abstract: Dynamic crusher for treading fruit, particularly grapes, with a treading chamber having, when considering the direction of the path followed by the fruit in the crusher, an upstream fruit-introduction opening, a downstream discharge opening for discharging the must that results from the treading, a rotary ejector that allows kinetic energy to be imparted to the fruit introduced into the treading chamber, and allows the fruit to be cast against a fixed fruit-bursting wall, wherein the rotary ejector is mounted such that it can rotate about a vertical axis and a fixed fruit-bursting wall is positioned around the rotary ejector or facing the peripheral edge thereof against which fruit is cast, rotation of which allows the fruit to be cast, under the effect of centrifugal force, against the fixed fruit-bursting wall, causing the fruit to burst. A method for dynamically treading fruit using such a crusher is also disclosed.

Abstract: The invention relates to chimera molecules for targeting and releasing therapeutic compounds in mammals, especially humans. The inventive molecules comprise essentially three functional segments or domains: a targeting segment that can preferentially bind to the surface of the targeted cells, a therapeutic segment comprising the biologically active compound, and a linker segment between the targeting segment and the therapeutic segment, the linker segment being cleavable onto the target site. The invention also relates to the preparation of said molecules, to synthesis intermediates or domains thereof, to pharmaceutical compositions containing the same, and to the use thereof, especially in the pharmaceutical field. The molecules and compositions according to the invention are especially adapted to the targeting of pathological cells engaged in an apoptotic phase, and to the treatment of pathologies or associated tissues, especially cancers and inflammation.