Abstract: The present disclosure provides an oil-in-water (O/W) emulsifier comprising esters of polyglycerol-6 and of fatty acids, and of polyglycerol-X, wherein X is any one of 4, 5 and 7 to 12 and of fatty acids, wherein the fatty acids are liquid fatty acids having a purity of at least 85% w/w, wherein the polyglycerols have a purity of at least 60% w/w, and wherein the emulsifier can form a stable O/W emulsion for at least 1 week at about 50° C. It also provides a method for making the emulsifier and emulsions comprising the emulsifier.

Abstract: The present disclosure provides an oil-in-water (O/W) emulsifier comprising esters of polyglycerol-6 and of fatty acids, and of polyglycerol-X, wherein X is any one of 4, 5 and 7 to 12 and of fatty acids, wherein the fatty acids are liquid fatty acids having a purity of at least 85% w/w, wherein the polyglycerols have a purity of at least 60% w/w, and wherein the emulsifier can form a stable O/W emulsion for at least 1 week at about 50° C. It also provides a method for making the emulsifier and emulsions comprising the emulsifier.

Abstract: Emulsifiers are provided that are able to stabilize water-in-oil emulsions. The emulsifiers are homogenous and have a relatively low melting point (e.g., soft pastes, gels or liquids at room temperature), enabling their use in cold-process methods/formulations which reduce energy consumption, manufacturing costs, as well as allow the use thermolabile active ingredients. The water-in-oil emulsifiers may comprise: (a) polyglycerol fatty acid esters consisting of saturated and unsaturated fatty acid esters of polyglycerol; (b) polyhydroxystearic acid copolymers consisting of copolymers of hydroxystearic acid with saturated and unsaturated fatty acids; and (c) hydroxystearic acid. Methods and uses relating to the emulsifiers are also described, for example in cosmetic and pharmaceutical compositions.

Abstract: The present invention relates to waxes useful for cosmetic applications having stable oil-in-water emulsion-forming properties and, in some embodiments, stable gel-in-water-forming properties. In some embodiments, the waxes exhibit self-emulsifying properties, and can be produced without the addition of any other substances to achieve the emulsion (e.g., co-emulsifiers, hydrophilic polymers, polar surfactants, rheological modifiers, gelling agents). The waxes generally comprise: (a) polyglyceryl fatty acid ester, (b) a glycerol fatty acid ester, and 9c) a fatty alcohol. In particular embodiments, the polyglyceryl fatty acid ester can be a polyglyceryl-2, -3, or -4 fatty acid ester, and the fatty chain lengths of (a)-(c) can range from C12 to C22. In more particular embodiments, the waxes can comprise polyglyceryl stearate, glyceryl stearate, and stearyl alcohol. Gels, oil-in-water emulsions, and other compositions produced from the waxes, as well as uses and methods relating thereto, are also disclosed.

Abstract: Emulsifiers are provided that are able to stabilize water-in-oil emulsions. The emulsifiers are homogenous and have a relatively low melting point (e.g., soft pastes, gels or liquids at room temperature), enabling their use in cold-process methods/formulations which reduce energy consumption, manufacturing costs, as well as allow the use thermolabile active ingredients. The water-in-oil emulsifiers may comprise: (a) polyglycerol fatty acid esters consisting of saturated and unsaturated fatty acid esters of polyglycerol; (b) polyhydroxystearic acid copolymers consisting of copolymers of hydroxystearic acid with saturated and unsaturated fatty acids; and (c) hydroxystearic acid. Methods and uses relating to the emulsifiers are also described, for example in cosmetic and pharmaceutical compositions.

Abstract: The present invention relates to waxes useful for cosmetic applications having stable oil-in-water emulsion-forming properties and, in some embodiments, stable gel-in-water-forming properties. In some embodiments, the waxes exhibit self-emulsifying properties, and can be produced without the addition of any other substances to achieve the emulsion (e.g., co-emulsifiers, hydrophilic polymers, polar surfactants, rheological modifiers, gelling agents). The waxes generally comprise: (a) polyglyceryl fatty acid ester, (b) a glycerol fatty acid ester, and 9c) a fatty alcohol. In particular embodiments, the polyglyceryl fatty acid ester can be a polyglyceryl-2, -3, or -4 fatty acid ester, and the fatty chain lengths of (a)-(c) can range from C12 to C22. In more particular embodiments, the waxes can comprise polyglyceryl stearate, glyceryl stearate, and stearyl alcohol. Gels, oil-in-water emulsions, and other compositions produced from the waxes, as well as uses and methods relating thereto, are also disclosed.

Abstract: A skin care composition comprising an isolated Asteroidea body fluid or extract thereof is described. Uses and methods of use of the composition for the prevention and/or treatment of a skin disorder or condition, such as skin-aging signs, are also described.

Abstract: The use of transesterified olive oil for increasing the penetration rate of cosmetically-active and/or dermatologically-active ingredients or as cosmetic moisturizer is disclosed.

Abstract: A lipophilic carrier composition comprising a lipophilic bioactive botanical extract, a vegetable oil, a solubilization system, and, optionally, an antioxidant, where the vegetable oil is present in a stable, relatively unoxidized state, is provided. Also provided is a lipophilic antioxidant composition comprising an antioxidant, a vegetable oil, and a solubilization system, but not comprising a lipophilic bioactive botanical extract, where the vegetable oil is present in a stable, relatively unoxidized state. Disclosed are methods of using the compositions to treat and/or protecting skin against erythema and/or skin barrier function loss as well as methods of using the compositions to treat age spots.

Abstract: A use of an anti-inflammatory polysaccharides composition comprising fucans and galactans to inhibit the release of one or more of IL-8, PGE2 and VEGF by a cell activated during an inflammatory process and an anti-inflammatory composition comprising a ratio of brown algae fucans/red algae galactans of between about 2.5/1 (w/w) to about 40/1 (w/w), the galactans having a molecular weight higher than about 100 kDa, and the fucans having a molecular weight between about 0.1 kDa and 100 kDa.

Abstract: The use of natural emulsifiers for the preparation of cosmetics comprising a wax, an active ingredient and an emulsifier which allows the formation of an oil-in-water emulsion is disclosed. Preferably, said natural emulsifier is olive oil transesterified with cetearyl alcohol and/or sorbitol.

Abstract: The use of—olive-oil—derived compounds as surfactants is described, wherein such olive-oil-derived compounds are obtained by olive oil transesterification. Preferably, such compounds are a mixture-composed of an emollient and of anionic surfactants. As an emollient a product obtained via transesterification of olive oil with glycerine derivatives is preferably used most preferably olive oil PEG-7 esters, whereas the anionic surfactant is obtained from the emollient by causing it to react with monochloroacetic acid most preferably Na PEG-7 olive oil Carboxylate.

Abstract: A skin care composition comprising an isolated Asteroidea body fluid or extract thereof is described. Uses and methods of use of the composition for the prevention and/or treatment of a skin disorder or condition, such as skin-aging signs, are also described.

Abstract: The use of transesterified olive oil for increasing the penetration rate of cosmetically-active and/or dermatologically-active ingredients or as cosmetic moisturiser is disclosed.

Abstract: A use of an anti-inflammatory polysaccharides composition comprising fucans and galactans to inhibit the release of one or more of IL-8, PGE2 and VEGF by a cell activated during an inflammatory process and an anti-inflammatory composition comprising a ratio of brown algae fucans/red algae galactans of between about 2.5/1 (w/w) to about 40/1 (w/w), the galactans having a molecular weight higher than about 100 kDa, and the fucans having a molecular weight between about 0.1 kDa and 100 kDa.