Patents by Inventor Alan Adams

Alan Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cooling system for a substrate
    Publication number: 20060262503
    Abstract: The present invention relates to a cooling system, the cooling system having a nozzle which receives coolant from a reservoir and which faces a substrate. The nozzle may be opened and closed by a thermally responsive valve allowing the coolant to be automatically metered to the substrate, thus controlling the spatial distribution of the coolant that is applied to the substrate. This approach allows hotter areas of the substrate to receive more coolant, thus eliminating nonuniformities in the thermal profile of the substrate.
    Type: Application
    Filed: December 22, 2005
    Publication date: November 23, 2006
    Inventors: Matthew Bevan, Keith Rebello, Alan Adams, Rafal Szczepanowski
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20060178398
    Abstract: The present invention relates to novel LXR ligands of Formula I and pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: September 14, 2005
    Publication date: August 10, 2006
    Inventors: Alan Adams, Shaei Huang, Jason Szewczyk
  • 2-Aryloxy-2-arylalkanoic acids for diabetes and lipid disorders
    Publication number: 20060122242
    Abstract: A class of 2-aryloxy-2-arylalkanoic acids comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.
    Type: Application
    Filed: January 18, 2006
    Publication date: June 8, 2006
    Inventors: Alan Adams, A. Jones, Joel Berger, James Dropinski, Alexander Elbrecht, Kun Liu, Karen MacNaul, Guo-Qiang Shi, Derek Von Langen, Gaochao Zhou
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050239769
    Abstract: The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: July 21, 2003
    Publication date: October 27, 2005
    Inventors: A. Jones, Alan Adams, Ahren Green, Shaei Huang, Bruno Tse, Clare Gutteridge, Yuan Cheng
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050113419
    Abstract: The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: October 26, 2004
    Publication date: May 26, 2005
    Inventors: Shaei Huang, Alan Adams
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050014807
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, are novel LXR ligands and are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: November 18, 2002
    Publication date: January 20, 2005
    Inventors: Alan Adams, Shaei Huang, Bruno Tse, A. Brian Jones
  • Antidiabetic agents based on aryl and heteroarylacetic acids
    Patent number: 6515015
    Abstract: The instant invention is concerned with aryl and heteroaryl acetic acid and oxyacetic acid compounds, which are useful as antidiabetic compounds. Compositions and methods for their use in the treatment of diabetes and related diseases and for lowering triglyceride levels are disclosed.
    Type: Grant
    Filed: October 24, 2000
    Date of Patent: February 4, 2003
    Assignee: Merck & Co. Inc.
    Inventors: Alan Adams, Derek Von Langen, Hiroo Koyama, Richard Tolman
  • Tris(hydroxymethyl)phosphino compounds as tissue crosslinking agents
    Publication number: 20020111532
    Abstract: A method of cross-linking a tissue, comprising treating the tissue under effective cross-linking conditions with a fluid comprising a compound comprising P(CH2OH)3Xn, wherein X is selected from C1-C10 carboxyl, sulfonic acid, sulfonic acid salts, C1-C10 alcohol, or halogens, and n is an integer from 0 to 2, inclusive, and all —X and —CH2OH groups are bonded to the phosphorus atom. In one embodiment, the compound is &bgr;-(tris(hydroxymethyl)phosphino)proprionic acid (THPP).
    Type: Application
    Filed: December 19, 2000
    Publication date: August 15, 2002
    Inventors: Chandrashekhar P. Pathak, Mark A. Moore, Richard E. Phillips, Alan Adams
  • Antidiabetic agents based on aryl and heteroarylacetic acids
    Patent number: 6160000
    Abstract: The instant invention is concerned with aryl and heteroaryl acetic acid and oxyacetic acid compounds, which are useful antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and related diseases and for lowering triglyceride levels are also disclosed.
    Type: Grant
    Filed: June 22, 1999
    Date of Patent: December 12, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Alan Adams, Derek Von Langen, Hiroo Koyama, Richard Tolman