Abstract: An improved disposable test strip for use in amperometric measurement of analytes in complex liquid media, such as blood, which has three or more electrodes has been developed. This strip is designed so that different electrical potentials can be maintained between a common pseudo reference/counter electrode and each of the other electrodes upon the imposition of a common potential by an amperometric meter. This capability is imparted to the test strip by providing different circuit resistances for each of these other electrodes. The test strip can be utilized to measure a single analyte such as glucose with a background compensation via a “dummy” electrode or it can be used to measure the concentration of multiple analytes.