Patents by Inventor Alan Archibald

Alan Archibald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Swine Comprising Modified CD163 and Associated Methods
    Publication number: 20200045945
    Abstract: The present invention relates to genetically edited swine which produce CD163 protein in which the scavenger receptor cysteine-rich 5 (SRCR5) domain (also known as CD163 domain 5) has been deleted. Such swine have been found to be healthy and do not exhibit negative properties, and are resistant to PRRSV infection. CD163 expressed in the edited swine also demonstrates retention of the ability to function as a haemoglobin-haptoglobin scavenger. Methods of producing such swine are also provided.
    Type: Application
    Filed: October 17, 2017
    Publication date: February 13, 2020
    Inventors: Simon Geoffrey Lillico, Alan Archibald, Christopher Bruce Alexander Whitelaw, Christine Tait-Burkard, Tahar Ait-Ali
  • Domain 5 of CD163 for use in antiviral compositions against PRRS, and transgenic animals
    Patent number: 9854790
    Abstract: The present invention relates to methods and compositions useful for the prevention and/or treatment of PRRS in animals, typically domestic pigs. The invention relates to proteins which comprise fragments of CD163, nucleic acid constructs encoding such proteins, and methods of modifying expression or activity of CD 163 in vivo.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: January 2, 2018
    Assignee: The University Court of the University of Edinburgh
    Inventors: Tahar Ait-Ali, Simon Lillico, Alan Archibald, Christopher Bruce Alexander Whitelaw
  • Domain 5 of CD163 for Use in Antiviral Compositions Against PRRS, and Transgenic Animals
    Publication number: 20160165860
    Abstract: The present invention relates to methods and compositions useful for the prevention and/or treatment of PRRS in animals, typically domestic pigs. The invention relates to proteins which comprise fragments of CD163, nucleic acid constructs encoding such proteins, and methods of modifying expression or activity of CD163 in vivo.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 16, 2016
    Applicant: The University Court of the University of Edinburg h
    Inventors: Tahar Ait-Ali, Simon Lillico, Alan Archibald, Christopher Bruce Alexander Whitelaw
  • Porcine polymorphisms and methods for detecting them
    Patent number: 7785778
    Abstract: Identification of a pig as resistant or non-resistant to enterotoxigenic E. Coli (ETEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of resistance/non-resistance, mixed boar semen, and methods for developing drugs to compensate for non-resistance to ETEC.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: August 31, 2010
    Assignee: University of Copenhagen
    Inventors: Claus Böttcher Jörgensen, Susanna Cirera, Alan Archibald, Leif Andersson, Merete Fredholm, Inger Edfors-Lilia
  • Porcine polymorphisms and methods for detecting them
    Publication number: 20060275763
    Abstract: Identification of a pig as resistant or non-resistant to enterotoxigenic E. Coli (EIEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of resistance/non-resistance, mixed boar semen, and methods for developing drugs to compensate for non-resistance to ETEC.
    Type: Application
    Filed: November 25, 2003
    Publication date: December 7, 2006
    Inventors: Claus Jorgensen, Susanna Cirera, Alan Archibald, Leif Andersson, Merete Fredholm, Inger Edfors-Lilia