Patents by Inventor Alan Aspuru-Guzik

Alan Aspuru-Guzik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240415014
    Abstract: The present application relates to compounds (e.g. Formulae III, V, VII, IX, and XII) having a negative singlet-triplet gap and a positive oscillator strength. The present application also relates to use of the compounds of the present application in photocatalysis and in OLEDs as emitters and/or dopants.
    Type: Application
    Filed: May 22, 2024
    Publication date: December 12, 2024
    Applicant: The Governing Council of the University of Toronto
    Inventors: Alán Aspuru-Guzik, AkshatKumar Nigam, Robert Pollice, Pascal Thomas Friederich, Benjamin Bangjie Ding
  • Publication number: 20240281693
    Abstract: A computer-implemented method and system for implementing a n-fold fermionic excitation generator using linear combination of directly differentiable operators on a quantum computer. Computer-readable data is generated and stored which when executed on the quantum computer, causes a quantum circuit of the quantum computer to execute repeatedly to perform a sequence of operations that implements the unitary (I) generated by a fermionic n-fold excitation operator G. The Gradient with respect to the angle ? of arbitrary expectation values involving the unitary operation can, in the general case, be evaluated by four expectation values obtained from replacing the corresponding unitary with fermionic shift operations (II). Fermionic shift operations can be constructed through the original unitary and unitary operations generated by the nullspace projector P0 of the fermionic excitation generator. Other operators and generators are disclosed.
    Type: Application
    Filed: October 19, 2021
    Publication date: August 22, 2024
    Inventors: Artur Izmaylov, Abhinav Anand, Jakob Kottmann, Alan Aspuru-Guzik, Robert Lang, Tzu-ching Yen
  • Publication number: 20230391787
    Abstract: The present application relates to compounds of Formula I having a negative singlet-triplet gap and a positive oscillator strength. The present application also relates to use of the compounds of Formula (I) in photocatalysis and in OLEDs as emitters and/or dopants.
    Type: Application
    Filed: October 8, 2021
    Publication date: December 7, 2023
    Inventors: Robert Pollice, Alan Aspuru-Guzik, Pascal Friederich, Cyrille Lavigne, Gabriel Dos Passos Gomes
  • Patent number: 11689223
    Abstract: Model-free error correction in quantum processors is provided, allowing tailoring to individual devices. In various embodiments, a quantum circuit is configured according to a plurality of configuration parameters. The quantum circuit comprises an encoding circuit and a decoding circuit. Each of a plurality of training states is input to the quantum circuit. The encoding circuit is applied to each of the plurality of training states and to a plurality of input syndrome qubits to produce encoded training states. The decoding circuit is applied to each of the encoded training states to determine a plurality of outputs. A fidelity of the quantum circuit is measured for the plurality of training states based on the plurality of outputs. The fidelity is provided to a computing node. The computing node determines a plurality of optimized configuration parameters. The optimized configuration parameters maximize the accuracy of the quantum circuit for the plurality of training states.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: June 27, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Alan Aspuru-Guzik, Jonathan P. Olson, Jhonathan Romero Fontalvo, Peter D. Johnson, Yudong Cao, Pierre-Luc Dallaire-Demers
  • Patent number: 11636370
    Abstract: A hybrid quantum-classical (HQC) computer which includes both a classical computer component and a quantum computer component performs generative learning on continuous data distributions. The HQC computer is capable of being implemented using existing and near-term quantum computer components having relatively low circuit depth.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: April 25, 2023
    Assignee: Zapata Computing, Inc.
    Inventors: Jhonathan Romero, Alan Aspuru-Guzik
  • Patent number: 11593707
    Abstract: A system and method include techniques for: generating, by a quantum autoencoder, based on a set of quantum states encoded in a set of qubits, a decoder circuit that acts on a subset of the set of qubits, a size of the subset being less than a size of the set; and generating a reduced-cost circuit, the reduced-cost circuit comprising: (1) a new parameterized quantum circuit acting only on the subset of the set of qubits, and (2) the decoder circuit.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: February 28, 2023
    Assignee: Zapata Computing, Inc.
    Inventors: Jhonathan Romero, Jonathan Olson, Alan Aspuru-Guzik
  • Publication number: 20230040234
    Abstract: The present invention relates generally to the design of quantum optical configurations and more specifically to using graph theory mapping and fidelity optimization to design optimal quantum optical configurations that have maximal fidelity between the designed optimal quantum optical configuration and the target quantum state. The target quantum state may include resource-efficient heralded multi-photonic quantum states, heralded high-dimensional entanglement, resource states for quantum gates, and high-dimensional multi-photonic GHZ states without ancilla photons.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 9, 2023
    Inventors: Alan Aspuru-Guzik, Mario Krenn, Jakob Kottmann
  • Patent number: 11551133
    Abstract: Preparation of correlated fermionic states on a quantum computer for determining a ground state of a correlated fermionic system is provided. In various embodiments, a quantum circuit is provided that comprises a linear chain of qubits and a plurality of matchgates arranged in layers. Each matchgate is configured to perform a two-qubit rotation on neighboring qubits within the linear chain. An initial state is provided for each qubit in the linear chain, The quantum circuit is applied to the initial values, thereby preparing an ansastz on the linear chain of qubits, the ansatz corresponding to a fermionic state.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 10, 2023
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Pierre-Luc Dallaire-Demers, Jhonathan Romero Fontalvo, Alan Aspuru-Guzik, Libor Veis
  • Publication number: 20220389414
    Abstract: Molecular computer techniques for solving a computational problem using an array of reaction sites, for example, droplets, are disclosed. The problem may be represented as a Hamiltonian in terms of problem variables and problem parameters. The reaction sites may have a physicochemical property mapping to discrete site states corresponding to possible values of the problem variables. In a purely molecular approach, the reaction sites have intra-site and inter-site couplings enforced thereon representing the problem parameters, and the array is allowed to evolve, subjected to the enforced couplings, to a final configuration conveying a solution to the problem. In a hybrid classical-molecular approach, an iterative procedure may be performed that involves feeding read-out site states into a digital computer, determining, based on the problem parameters, perturbations to be applied to the states, and allowing the array to evolve under the perturbations to a final configuration conveying a solution to the problem.
    Type: Application
    Filed: October 28, 2020
    Publication date: December 8, 2022
    Inventors: Alan ASPURU-GUZIK, Si Yue GUO, Tony Chang-Chi WU, Pascal Thomas FRIEDERICH, Randall Howard GOLDSMITH, Leroy CRONIN, Abhishek SHARMA, Yudong CAO, Nathan C. GIANNESCHI, Christopher James FORMAN
  • Patent number: 10963793
    Abstract: Solution of a problem of determining values of a set of N problem variables xi makes use of a quantum processor that has a limited number of hardware elements for representing quantum bits and/or limitations on coupling between quantum bits. A method includes accepting a specification of the problem that includes a specification of a set of terms where each term corresponds to a product of at least three variables and is associated with a non-zero coefficient. A set of ancilla variables, each ancilla variable corresponding to a pair of problem variables, is determined by applying an optimization procedure to the specification of the set of the terms. The accepted problem specification is then transformed according to the determined ancilla variables to form a modified problem specification for use in configuring the quantum processor and solution of problem.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: March 30, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Alan Aspuru-Guzik, Ryan Babbush, Bryan O'Gorman
  • Publication number: 20210083311
    Abstract: The invention provides an electro-chemical cell based on a new chemistry for a flow battery for large scale, e.g., gridscale, electrical energy storage. Electrical energy is stored chemically in quinone molecules having multiple oxidation states, e.g., three or more. During charging of the battery, the quinone molecules at one electrode are oxidized by emitting electrons and protons, and the quinone molecules at the other electrode are reduced by accepting electrons and protons. These reactions are reversed to deliver electrical energy. The invention also provides additional high and low potential quinones that are useful in rechargeable batteries.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 18, 2021
    Inventors: Brian HUSKINSON, Michael MARSHAK, Michael J. AZIZ, Roy G. GORDON, Alan ASPURU-GUZIK, Suleyman ER, Changwon SUH, Liuchuan TONG, Kaixiang LIN
  • Patent number: 10922617
    Abstract: Generating a computing specification to be executed by a quantum processor includes: accepting a problem specification that corresponds to a second-quantized representation of a fermionic Hamiltonian, and transforming the fermionic Hamiltonian into a first qubit Hamiltonian including a first set of qubits that encode a fermionic state specified by occupancy of spin orbitals. An occupancy of any spin orbital is encoded in a number of qubits that is logarithmic in the number of spin orbitals, and a parity for a transition between any two spin orbitals is encoded in a number of qubits that is logarithmic in the number of spin orbitals. An eigenspectrum of a second qubit Hamiltonian, including the first set of qubits and a second set of qubit, includes a low-energy subspace and a high-energy subspace, and an eigenspectrum of the first qubit Hamiltonian is approximated by a set of low-energy eigenvalues of the low-energy subspace.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: February 16, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Ryan Babbush, Peter Love, Alan Aspuru-Guzik
  • Publication number: 20200410384
    Abstract: Hybrid quantum-classical generative models for learning data distributions are provided. In various embodiments, methods of and computer program products for operating a Helmholtz machine are provided. In various embodiments, methods of and computer program products for operating a generative adversarial network are provided. In various embodiments, methods of and computer program products for variational autoencoding are provided.
    Type: Application
    Filed: September 10, 2020
    Publication date: December 31, 2020
    Inventors: Alan Aspuru-Guzik, Yudong Cao, Peter D. Johnson
  • Publication number: 20200394549
    Abstract: Preparation of correlated fermionic states on a quantum computer for determining a ground state of a correlated fermionic system is provided. In various embodiments, a quantum circuit is provided that comprises a linear chain of qubits and a plurality of matchgates arranged in layers. Each matchgate is configured to perform a two-qubit rotation on neighboring qubits within the linear chain. An initial state is provided for each qubit in the linear chain, The quantum circuit is applied to the initial values, thereby preparing an ansastz on the linear chain of qubits, the ansatz corresponding to a fermionic state.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 17, 2020
    Inventors: Pierre-Luc Dallaire-Demers, Jhonathan Romero Fontalvo, Alan Aspuru-Guzik, Libor Veis
  • Patent number: 10847829
    Abstract: The invention provides an electrochemical cell based on a new chemistry for a flow battery for large scale, e.g., gridscale, electrical energy storage. Electrical energy is stored chemically in quinone molecules having multiple oxidation states, e.g., three or more. During charging of the battery, the quinone molecules at one electrode are oxidized by emitting electrons and protons, and the quinone molecules at the other electrode are reduced by accepting electrons and protons. These reactions are reversed to deliver electrical energy. The invention also provides additional high and low potential quinones that are useful in rechargeable batteries.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: November 24, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Brian Huskinson, Michael Marshak, Michael J. Aziz, Roy G. Gordon, Alan Aspuru-Guzik, Suleyman Er, Changwon Suh, Liuchuan Tong, Kaixiang Lin
  • Publication number: 20200321533
    Abstract: Described herein are molecules for use in organic light emitting diodes comprising at least one moiety A, at least one moiety D, and at least one moiety B.
    Type: Application
    Filed: May 23, 2017
    Publication date: October 8, 2020
    Inventors: Alan Aspuru-Guzik, Rafael Gomez-Bombarelli, Timothy D. Hirzel, Jorge Aguilera-Iparraguirre, Phil Baran
  • Publication number: 20200274554
    Abstract: Model-free error correction in quantum processors is provided, allowing tailoring to individual devices. In various embodiments, a quantum circuit is configured according to a plurality of configuration parameters. The quantum circuit comprises an encoding circuit and a decoding circuit. Each of a plurality of training states is input to the quantum circuit. The encoding circuit is applied to each of the plurality of training states and to a plurality of input syndrome qubits to produce encoded training states. The decoding circuit is applied to each of the encoded training states to determine a plurality of outputs. A fidelity of the quantum circuit is measured for the plurality of training states based on the plurality of outputs. The fidelity is provided to a computing node. The computing node determines a plurality of optimized configuration parameters. The optimized configuration parameters maximize the accuracy of the quantum circuit for the plurality of training states.
    Type: Application
    Filed: September 14, 2018
    Publication date: August 27, 2020
    Inventors: Alan Aspuru-Guzik, Jonathan P. Olson, Jhonathan Romero Foniaivo, Peter D. Johnson, Yudong Cao, Pierre-Luc Dallaire-Demers
  • Publication number: 20200272930
    Abstract: A quantum circuit that functions a neuron and a method for configuring same. The quantum circuit comprises a Repeat-Until-Success (RUS) circuit that includes an input register, comprising at least one input qubit; an ancilla qubit; and an output qubit. The method for configuring the quantum neuron comprises: encoding an input quantum state in the at least one input qubit; and applying the first RUS circuit to the ancilla qubit and to the output qubit of the first RUS circuit, wherein the first RUS circuit is controlled by the input quantum state.
    Type: Application
    Filed: September 14, 2018
    Publication date: August 27, 2020
    Inventors: Alan Aspuru-Guzik, Yudortg Cao
  • Publication number: 20200243773
    Abstract: An organic light-emitting device including a first electrode; a second electrode; and an organic layer disposed between the first electrode and the second electrode, wherein the organic layer comprises an emission layer, and wherein the organic layer comprises a first compound represented by Formula 1 and a second compound having the lowest excited triplet energy level greater than 2.73 electron volts: wherein in Formula 1, R11 to R33 are the same as described in the specification.
    Type: Application
    Filed: April 13, 2020
    Publication date: July 30, 2020
    Inventors: Hyun Sik CHAE, Soonok JEON, Hosuk KANG, Hiroshi MIYAZAKI, Sooghang IHN, Seongik HONG, Masaki NUMATA, Sunghan KIM, Rafael GOMEZ-BOMBARELLI, Martin B.Z. FORSYTHE, Jorge AGUILERA-IPARRAGUIRRE, Alan ASPURU-GUZIK, Timothy D. HIRZEL
  • Publication number: 20200242501
    Abstract: Generating a computing specification to be executed by a quantum processor includes: accepting a problem specification that corresponds to a second-quantized representation of a fermionic Hamiltonian, and transforming the fermionic Hamiltonian into a first qubit Hamiltonian including a first set of qubits that encode a fermionic state specified by occupancy of spin orbitals. An occupancy of any spin orbital is encoded in a number of qubits that is logarithmic in the number of spin orbitals, and a parity for a transition between any two spin orbitals is encoded in a number of qubits that is logarithmic in the number of spin orbitals. An eigenspectrum of a second qubit Hamiltonian, including the first set of qubits and a second set of qubit, includes a low-energy subspace and a high-energy subspace, and an eigenspectrum of the first qubit Hamiltonian is approximated by a set of low-energy eigenvalues of the low-energy subspace.
    Type: Application
    Filed: August 8, 2019
    Publication date: July 30, 2020
    Inventors: Ryan Babbush, Peter Love, Alan Aspuru-Guzik